Anxiety and sleep disorders in general practice DOI

O. A. Polyakova,

E. Yu. Ebzeeva, A.V. Dubinina Dubinina

и другие.

Medical alphabet, Год журнала: 2023, Номер 13, С. 28 - 35

Опубликована: Окт. 18, 2023

Anxiety and sleep disorders are an urgent problem of modern healthcare, which should be treated at the earliest possible stages, since this would prevent development a wide range complications these conditions. At same time, given bidirectional relationship between anxiety disorders, search safe effective remedies for their correction is becoming increasingly relevant. The prescription set measures nonmedicamental medicamental nature considered to main methods therapy disorders. This article presents diagnostic tools that allow general practitioner identify (insomnia) in patient as early possible, discusses therapeutic strategies using combination glycine melatonin appropriate patients.

Язык: Английский

Simple and effective solutions in the correction of anxiety and stress DOI Creative Commons
V. N. Shishkova

Meditsinskiy sovet = Medical Council, Год журнала: 2023, Номер 3, С. 161 - 167

Опубликована: Апрель 12, 2023

Acute and chronic stress conditions have an adverse effect on human health at any age are related to the psychosocial risk factors for non-communicable diseases, increasing of occurrence development not only cardiovascular, but also other common diseases such as diabetes mellitus, obesity, broncho-obstructive ulcerative lesions gastrointestinal tract, etc. The negative is effectuated both through endogenous pathophysiological changes behavioural disorders physical inactivity, malnutrition, smoking, alcohol intake, It has been shown that significantly aggravate clinical course existing reduce adherence treatment, worsen quality life, increase disability expenditures paid in healthcare system patients with diseases. Thus, acute a physical, mental emotional health, that's why right choice preventive measures timely management very important. combination non-pharmaceutical effect, including training resistance skills, proper response emergency self-help stressful situation, prescription effective pharmacological therapy can be considered optimal strategy. Valocordin® available form drops or tablets represents low doses phenobarbital ethyl bromisovalerianate plant components, which enhances positive effects due functional.

Язык: Английский

Процитировано

10

COVID-19 pandemic: Emotional burnout in nurses (3 years later). DOI

M.M. Khabibulina,

M.D. Shamilov

Meditsinskaya sestra, Год журнала: 2024, Номер 26(2), С. 51 - 56

Опубликована: Март 1, 2024

Introduction. During the COVID-19 pandemic, crises occurred in various spheres of life – health, politics, economics, education, etc. Medical staff turned out to be a more vulnerable category terms risk developing emotional burnout. The problems that doctors had face contributed huge increase workload, as well increased susceptibility burnout and stress. aim study is investigate COVID nurses hospitals, polyclinics hospitals 3 years after pandemic. Material methods. To achieve purpose study, survey analysis were conducted among who worked “red zone” (n=73); polyclinic (n=78) multidisciplinary (n=77), control group (n=79). syndrome, Maslach Burnout questionnaire was used conducted, which allowed us assess attitude nursing situation processing obtained data carried using statistical package “Statistica”. Results. It revealed their colleagues from according results have indicators hospital significantly higher characteristics “occupational exhaustion” “depersonalization” compared (p≤0.001) outpatient (p≤0.001). should noted lower indicator “reduction personal achievements” clinics. Risk factors affect psychological health during pandemic been identified: changes organization work, infection social isolation. Conclusions. all three groups professional Thus, rates “professional exhaustion”, low values achievements”, with clinics, even years. treatment patients exposes physicians specific associated care infected patients, significant safety-related aspects contribute stress

Язык: Английский

Процитировано

3

MOLECULAR MECHANISMS UNDERLYING THERAPEUTIC ACTION OF VITAMIN B6 DOI Creative Commons
Olga A. Zagubnaya, Yaroslav R. Nartsissov

Pharmacy & Pharmacology, Год журнала: 2023, Номер 10(6), С. 500 - 514

Опубликована: Фев. 12, 2023

The aim of the study was to analyze molecular mechanisms that determine possibility using vitamin B 6 in clinical practice for correction various pathological conditions. Materials and methods. Information retrieval (Scopus, PubMed) library (eLibrary) databases were used as research tools. In some cases, ResearchGate application a semantic search. analysis generalization scientific literature on topic research, covering period from 1989 present, has been carried out work. Results. It shown all chemical forms are able penetrate membranes most cells by free diffusion, while forming phosphorylated inside. Pyridoxal phosphate is biologically important metabolite directly involved cofactor variety intracellular reactions. Requirements this depend age, sex condition patient. Pregnancy lactation play special role consumption . balanced diet will provide an acceptable level vitamin. At same time, its deficiency leads development number conditions, including neurodegenerative diseases, inflammations diabetes. Negative manifestations central nervous system also possible with excessive Conclusion. Replenishment case identified necessary successful treatment diabetes patients’ immune status. it observe intake order avoid negative effects metabolism excess.

Язык: Английский

Процитировано

4

A functional drink based on reconstituted whey powder and a triple chelate complex of the essential trace element zinc DOI Open Access

K. Kostenko,

А.В. Блинов,

Ph. A. Poydun

и другие.

Agrarian science, Год журнала: 2024, Номер 12, С. 158 - 165

Опубликована: Дек. 18, 2024

In this work, a functional drink was obtained based on reconstituted dry whey and triple chelate complex of the essential trace element zinc. The synthesis carried out by mechanically mixing 3-pyridinecarboxamide, L-lysine monohydrochloride, barium hydroxide 8-aqueous zinc sulfate 7-aqueous with addition 30 ml distilled water. Next, absorption spectrum sample obtained, using which maximum band (λ = 260 nm) determined. At next stage, computer quantum-chemical modeling out, as result it determined that interaction 3-pyridinecarboxamide occurs through secondary amino group carboxyl α-amino group, respectively. Then, optimization technique out. Using neural network data processing, found optimal concentrations components are: C (ZnSO 4 ) 0.376 mol/l, (C 6 H 5 NO 2 0.545 14 N O 0.528 mol/l. milk containing 7.5% whey, molasses 0.13 complex. Then subjected to ultrasonic treatment different amplitudes. titratable acidity, electrical conductivity, pH, antioxidant activity average hydrodynamic radius were studied. As result, when adding drink, well at amplitude ultrasound treatment, an increase in decrease are observed, allows us conclude use is beneficial, conducting amplitude. organoleptic assessment resulting for implementation dairy industry enterprises, recommended enriched complex,

Язык: Английский

Процитировано

1

Experience of effective correction of the main manifestations of postcovid syndrome DOI Creative Commons
V. N. Shishkova, В. А. Шишков, D. B. Ustarbekova

и другие.

Meditsinskiy sovet = Medical Council, Год журнала: 2023, Номер 10, С. 168 - 176

Опубликована: Июль 24, 2023

Introduction. Postcovid syndrome is an urgent problem, due to its high frequency regardless of the severity infection and age patient. Aim. To evaluate efficacy safety use a dietary supplement Metabovit ® Healthy Sleep with Glycine Zinc in patients postcovid syndrome. Materials methods. 50 were included study, after randomization, was added therapy group 1 (2 tablets 3 times day), 2 received basic for chronic diseases. The duration observation 21 days. Before end study all underwent clinical neuropsychological examination, which included: complaint analysis, “Schulte tables” test, verbal association Trail Making Test, MFI-20 self-questionnaire, Reader questionnaire on level life exhaustion, hospital scale anxiety depression (HADS). Results. In receiving day, comparison control group, overall self-questionnaire score sugnificantly (p < 0.001) decreased by 16 [-19, -8] 59 [52; 63] points performance time "Schulte tables" test more than 13 seconds; Test 26 seconds faster part A 40 B, results reached normative values most participants; stress levels almost 25% men 11% women; indicator exhaustion 22%; (HADS score) 5 [-7; -3] led normalization this participants group. By no significant changes studied parameters detected Conclusion. who supplement, there positive dynamics regression symptoms syndrome,

Язык: Английский

Процитировано

2

Experience of pyridoxin and glutamic acid use in effective correction of the main asthenia manifestations DOI Creative Commons
V. N. Shishkova, В. А. Шишков, L. A. Kapustina

и другие.

Meditsinskiy sovet = Medical Council, Год журнала: 2024, Номер 23, С. 80 - 89

Опубликована: Янв. 19, 2024

Introduction. Asthenia manifestation treatment is an urgent problem due to its high frequency in outpatients. Аim. To evaluate a controlled randomized clinical trial the efficacy and tolerability of course use combination pyridoxine glutamic acid patients with asthenic complaints. Materials methods . 50 outpatients main asthenia manifestations were included study if they complied inclusion criteria signed informed consent. After randomization, group 1 combined supplement 2.5 mg pyridoxin 100 (Metabovit® Life Energy, MNPK “BIOTIKI”) was added therapy tablet day sublingually, 2 received basic for chronic diseases only. The duration observation 21 days. Before after end all underwent neuropsychological examination, which questionnaires: Multidimensional Fatigue Inventory (MFI-20), Reader stress test (adopted by O.Kopina), questionnaire on level life exhaustion (The Maastricht Questionnaire), “Schulte tables” working efficiency evaluation. Results. In receiving Metabovit® Energy day, comparison control (p < 0.001) overall score MFI-20 self-questionnaire decreased amounted 29 [26; 30]; Δ equal -22 [-27; -16]; results reached normative values most participants; improved time performance more than 9 seconds; levels almost 30% men 20% women; indicator 60%. group, no significant changes studied indicators detected follow-up. Conclusion. who biologically active food there positive dynamics regression symptoms asthenia, group.

Язык: Английский

Процитировано

0

Metabolic therapy in the treatment of cardiovascular diseases DOI Creative Commons
V. S. Kopylova, S E Boronovskiy, L. P. Sokolova

и другие.

Meditsinskiy sovet = Medical Council, Год журнала: 2024, Номер 13, С. 46 - 55

Опубликована: Сен. 1, 2024

Today, cardio- and cerebrovascular diseases pose a severe threat to human health life quality, leading reduced working capacity, disability and, often, death. The most common cardiovascular are arterial hypertension, chronic cerebral ischemia ischemic heart disease. Metabolic disorders that cause oxidative stress growth, vessel wall damage, injury of body cells tissues, as well affect energy formation processes the key aspects their formation. Glutathione is powerful antioxidant protects cell structures from damage by free radicals, helping reduce stress. Eltacin has corrective effect on these pathological processes, rising protection increasing efficiency glutathione-dependent mechanisms redox regulation. As result complex impact metabolic in tissue, not only antioxidant, but also neuro- cytoprotective vegetotropic effects. drug positive hemodynamic performance patients with diseases, which expressed blood flow normalization brain. inclusion traditional therapy for leads an increase antianginal hypotensive Its use combined treatment regimens contributes structural functional state improvement myocardium left ventricle, factor maintaining normal functioning. Increased physical activity tolerance allows lead more active lifestyle, beneficial overall condition quality. In addition, effectiveness been proven. It results meteoprotective effect, reduces weather factors influence hemodynamics weather-dependent hypertension Thus, improves increases effectiveness, provides additional adverse environmental influence.

Язык: Английский

Процитировано

0

Iodine deficiency in Russia: Current state of the problem, global practice and new approaches to therapy DOI Creative Commons

Irina Barkovskaya,

А.Г. Кручинин, И.В. Рожкова

и другие.

Food systems, Год журнала: 2024, Номер 7(2), С. 238 - 245

Опубликована: Июль 17, 2024

Iodine performs a number of important functions in the body, participating synthesis thyroid hormones, which creates need for constant replenishment element adequate amounts. Continuous monitoring micronutrient deficiency Russian Federation reveals low average daily iodine intake and an increase cases diseases period from 2010 to 2020. This actualizes develop new therapeutic preventive approaches replenish deficiency. The aim review is analyze problem Russia existing practices its leveling order approach prevention treatment conditions. sample includes publications English 2002 2023, using resources scientific metric databases Elibrary, Google Scholar, CyberLeninka, PubMed ScienceDirect. research work showed that common practice eliminating level consumption trace diet, consequence availability wide range iodized food supplements products on market. However, analysis current functional nutrition sector has revealed drawbacks associated with bioavailability resistance technological factors production products. article presents key influencing effectiveness nutritional being developed correction They are based evaluation means prevention. study proposes development technology whey hydrolysates enriched zinc. Application additive protein components milk opens opportunities processing secondary dairy raw materials full utilization all components. rich amino acid composition helps concentration essential elements products, as residues able bind chelate

Язык: Английский

Процитировано

0

Experience of Taiwan-Russian healthcare cooperation model building using Internet technologies DOI Creative Commons
O. V. Goncharova,

Grace Lo

Journal of the Formosan Medical Association, Год журнала: 2024, Номер 123(11), С. 1122 - 1123

Опубликована: Авг. 23, 2024

Язык: Английский

Процитировано

0

Anxiety and sleep disorders in general practice DOI

O. A. Polyakova,

E. Yu. Ebzeeva, A.V. Dubinina Dubinina

и другие.

Medical alphabet, Год журнала: 2023, Номер 13, С. 28 - 35

Опубликована: Окт. 18, 2023

Anxiety and sleep disorders are an urgent problem of modern healthcare, which should be treated at the earliest possible stages, since this would prevent development a wide range complications these conditions. At same time, given bidirectional relationship between anxiety disorders, search safe effective remedies for their correction is becoming increasingly relevant. The prescription set measures nonmedicamental medicamental nature considered to main methods therapy disorders. This article presents diagnostic tools that allow general practitioner identify (insomnia) in patient as early possible, discusses therapeutic strategies using combination glycine melatonin appropriate patients.

Язык: Английский

Процитировано

0