Molecules, Год журнала: 2025, Номер 30(6), С. 1253 - 1253

Опубликована: Март 11, 2025

Chronic liver diseases (CLDs), including fatty disease, fibrosis, and cirrhosis, pose significant global health challenges due to the limitedness of therapeutic options. Flavonoids, a class polyphenolic compounds mainly contained in natural sources foods Mediterranean diet, have emerged as potential candidates for protection their anti-inflammatory, antioxidant, anti-fibrotic properties. Baicalein, derived from Scutellaria baicalensis, exhibits hepatoprotective effects by attenuating oxidative stress, inhibiting fibrogenesis, modulating lipid metabolism. Galangin, flavonoid Alpinia officinarum, has demonstrated anti-inflammatory properties, while isorhamnetin, methylated found various fruits herbs, been shown possess qualities, it reduces stress mitigates inflammation CLDs. This narrative review highlights preventive these three flavonoids, emphasizing role promising agents managing CLDs guiding future research.

Язык: Английский