Extracellular Vesicle-Based Drug Delivery Systems in Cancer Therapy

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(10), С. 4835 - 4835

Опубликована: Май 19, 2025

Extracellular vesicles (EVs) are lipid bilayer-enclosed particles secreted by cells and ubiquitously present in various biofluids. They not only mediate intercellular communication but also serve as promising drug carriers that capable of delivering therapeutic agents to target through their inherent physicochemical properties. In this review, we summarized the recent advances EV isolation techniques innovative drug-loading strategies. Furthermore, emphasized distinct advantages applications EVs derived from different cellular sources cancer treatment. Finally, critically evaluated ongoing clinical trials utilizing for delivery systematically assessed both opportunities challenges associated with implementing EV-based systems therapy.

Язык: Английский

Proposing plant-derived extracellular vesicles as sustainable and safe bioactive nanocarriers for target-specific human skin transdermal therapeutics strategies

Sustainable materials and technologies, Год журнала: 2025, Номер unknown, С. e01456 - e01456

Опубликована: Май 1, 2025

Язык: Английский