The magic Triangle in Oral Potentially Malignant Disorders: Vitamin D, Vitamin D Receptor, and Malignancy DOI Open Access
Aya Khamis,

Lara Salzer,

Eik Schiegnitz

и другие.

Опубликована: Сен. 7, 2023

OPMDs (Oral Potentially Malignant Disorders) are a group of disorders affecting the oral mucosa that characterized by aberrant cell proliferation and higher risk malignant transformation. Vitamin D (VitD) its receptor (VDR) have been extensively studied for their potential contributions to prevention therapeutic management range diseases neoplastic conditions, including cancer. Observational studies suggest correlations between VitD deficiency cancer risk, worse prognosis, increased mortality rates. Interestingly, emerging data also reveals link insufficiency onset or progression OPMDs. Understanding role VitD-VDR axis not only in established tumors but might thus enable early detection With this article, we want provide an overview current knowledge about VitD, investigate association ramifications clinical

Язык: Английский

The magic Triangle in Oral Potentially Malignant Disorders: Vitamin D, Vitamin D Receptor, and Malignancy DOI Open Access
Aya Khamis,

Lara Salzer,

Eik Schiegnitz

и другие.

Опубликована: Сен. 7, 2023

OPMDs (Oral Potentially Malignant Disorders) are a group of disorders affecting the oral mucosa that characterized by aberrant cell proliferation and higher risk malignant transformation. Vitamin D (VitD) its receptor (VDR) have been extensively studied for their potential contributions to prevention therapeutic management range diseases neoplastic conditions, including cancer. Observational studies suggest correlations between VitD deficiency cancer risk, worse prognosis, increased mortality rates. Interestingly, emerging data also reveals link insufficiency onset or progression OPMDs. Understanding role VitD-VDR axis not only in established tumors but might thus enable early detection With this article, we want provide an overview current knowledge about VitD, investigate association ramifications clinical

Язык: Английский

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