Potential of Carbon Nanodots (CNDs) in Cancer Treatment
Walaa Alibrahem,
Nihad Kharrat Helu,
Csaba Oláh
и другие.
Nanomaterials,
Год журнала:
2025,
Номер
15(7), С. 560 - 560
Опубликована: Апрель 6, 2025
Carbon
Nanodots
(CNDs)
are
characterized
by
their
nanoscale
size
(<10
nm),
biocompatibility,
stability,
fluorescence,
and
photoluminescence,
making
them
a
promising
candidate
for
cancer
therapy.
The
difference
in
the
methods
of
synthesis
CNDs,
whether
top-down
or
bottom-up,
affects
formation,
visual,
surface
characteristics
which
crucial
biomedical
pharmaceutical
applications.
urgent
need
innovative
therapeutic
strategies
from
CNDs
is
due
to
limitations
barriers
posed
conventional
therapies
including
drug
resistance
cytotoxicity.
Nano-loaded
chemotherapy
treatments
highly
effective
can
enhance
solubility
targeted
delivery
chemotherapeutic
agents,
generate
reactive
oxygen
species
(ROS)
induce
cell
cytotoxicity,
regulate
intracellular
signaling
pathways.
Their
ability
be
designed
cellular
uptake
exact
localization
further
improves
potential.
In
addition
working
on
delivery,
highlighted
dual
functionality
imaging
therapy,
allows
real-time
observing
treatment
efficacy.
Despite
development
these
results
future,
challenges
still
exist
treatment.
Язык: Английский
Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review
Опубликована: Окт. 23, 2023
The
dynamic
interaction
between
carbon
nanodots
(CNDs)
and
cannabidiol
(CBD)
has
captured
significant
attention
as
an
innovative
avenue
for
redefining
drug
delivery
amplifying
therapeutic
effectiveness.
This
in-depth
review
delves
into
the
intricate
synergy
these
two
elements,
unveiling
their
profound
potential
in
medicine.
Commencing
with
examination
of
unique
characteristics
CNDs
techniques
governing
synthesis,
we
discuss
versatility
carriers,
highlighting
invaluable
role
advancing
CBD
delivery.
Cannabidiol,
a
non-psychoactive
compound
sourced
from
cannabis,
emerged
focal
point
its
diverse
attributes.
Nevertheless,
limitations
posed
by
restricted
bioavailability
susceptibility
to
degradation
pose
substantial
hindrances
realizing
full
potential.
Here,
elucidate
how
amalgamation
transcends
challenges.
We
delve
mechanisms
that
underlie
this
synergy,
such
augmentation
solubility
safeguarding
against
premature
breakdown,
providing
analysis.
will
also
journey
you
through
comprehensive
exploration
loading
onto
CNDs,
dissecting
realms
physical
encapsulation,
covalent
bonding,
adsorption
processes.
In
summation,
combination
presents
extraordinary
opportunity
elevate
outcomes.
synergetic
paradigm
masterfully
tackles
pivotal
challenges
delivery,
thereby
paving
path
pioneering
medical
solutions.
Язык: Английский