Universal mRNA-based HIV Vaccine for Acute and Latent Infections DOI Open Access
Sarfaraz K. Niazi,

Matthias Magoola

Опубликована: Март 18, 2024

Human Immunodeficiency Virus (HIV) infection and its latent recurrent make vaccine development a significant challenge for traditional vaccines; however, the mRNA delivery of multiepitope antigens capable creating antibodies against surface proteins HIV-1 HIV-2 along with their respective Nef proteins, responsible can bring most effective, as well affordable solution to unresolved epidemics HIV. In this paper, we present complete design prevent acute infections inactivate that block MHC-1 MHC-2 pathways hide virus later reinfection.

Язык: Английский

Universal mRNA-based HIV Vaccine for Acute and Latent Infections DOI Open Access
Sarfaraz K. Niazi,

Matthias Magoola

Опубликована: Март 18, 2024

Human Immunodeficiency Virus (HIV) infection and its latent recurrent make vaccine development a significant challenge for traditional vaccines; however, the mRNA delivery of multiepitope antigens capable creating antibodies against surface proteins HIV-1 HIV-2 along with their respective Nef proteins, responsible can bring most effective, as well affordable solution to unresolved epidemics HIV. In this paper, we present complete design prevent acute infections inactivate that block MHC-1 MHC-2 pathways hide virus later reinfection.

Язык: Английский

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