Опубликована: Май 6, 2024

Coronaviruses cause infections in humans and diverse species of animals birds with a global distribution. Bovine coronavirus (BCoV) produces predominantly two forms disease cattle, respiratory form, gastrointestinal form. All age groups cattle are affected by the form whereas gastroenteric causes neonatal diarrhea or calf scour young winter dysentery adult cattle. The tremendous impacts bovine associated losses well-documented underscores importance this pathogen. Beyond this, studies have demonstrated significant on milk production outbreaks dysentery, up to 30% decrease yield. Research data so far shown that viral structure strain is not determinant tissue tropism clinical disease. In North America, BCoV was identified for first time 1972, it continues be economic concern industry. virus classified under Coronaviridae family, Betacoronavirus genus Betacorovirus 1 species. A number conventional molecular diagnostic assays available detection from samples. Conventional include isolation, which challenging samples, electron microscopy, fluorescent antibody assays, various immunoassays. Molecular tests mainly based nucleic acid real-time polymerase chain reaction (PCR) assays. Isothermal amplification genome sequencing also been used increasingly recent years identification BCoV. Loop-mediated isothermal amplification, helicase-dependent recombinase multienzyme rapid some examples Point-of-care testing has gained popularity recently as they can offer user-friendly farm (barn-side). present study reviewed literature last three half decades presents information current advancing diagnostics addition epidemiology, presentations, impact

Язык: Английский