Опубликована: Май 15, 2024
Viral tropism is most commonly linked to receptor use, but host cell protease use can be a notable factor in susceptibility infection. Here we review the of proteases by human viruses, focusing on those with primarily respiratory tropism, particularly SARS-CoV-2. We first describe various classes present tract, as well elsewhere body, and incorporate targeting these therapeutic drugs for humans. Host are also systemic spread viruses play important roles outside tract; therefore, address how affect across spectrum infections that occur humans, intending understand extrapulmonary
Язык: Английский