The Role of Indigestible Oligosaccharides in Alleviating Human Chronic Diseases by Regulating Gut Microbiota: A Review DOI Open Access

Meiyu Yuan,

Zhongwei Zhang,

Tongying Liu

и другие.

Опубликована: Июнь 3, 2024

The gut has been a focus of chronic disease research. microbiota produces metabolites that act as signaling molecules and substrates, closely influencing host health. Indigestible oli-gosaccharides (NDOs), common dietary fiber, play an important role in regulating the structure function microbiota. Their mechanism action is mainly attributed to their carbon source specific probiotics, producing related metabolites, mi-crobial community. However, due selective utilization oligosaccharides, some factors such types structures oligosaccharides have different impacts on composition microbial populations production colon ecosystem. This review systematically describes key microorganisms elaborates how affect host's immune system, inflam-mation levels energy metabolism by diversity metabolic function, which turn will onset progress diseases, especially diabetes, obesity, depression intestinal inflammatory constipation. In this review, we re-examine interaction mechanisms between its associated explore new strategies for promoting human health combating diseases through di-etary interventions.

Язык: Английский

The Role of Indigestible Oligosaccharides in Alleviating Human Chronic Diseases by Regulating Gut Microbiota: A Review DOI Open Access

Meiyu Yuan,

Zhongwei Zhang,

Tongying Liu

и другие.

Опубликована: Июнь 3, 2024

The gut has been a focus of chronic disease research. microbiota produces metabolites that act as signaling molecules and substrates, closely influencing host health. Indigestible oli-gosaccharides (NDOs), common dietary fiber, play an important role in regulating the structure function microbiota. Their mechanism action is mainly attributed to their carbon source specific probiotics, producing related metabolites, mi-crobial community. However, due selective utilization oligosaccharides, some factors such types structures oligosaccharides have different impacts on composition microbial populations production colon ecosystem. This review systematically describes key microorganisms elaborates how affect host's immune system, inflam-mation levels energy metabolism by diversity metabolic function, which turn will onset progress diseases, especially diabetes, obesity, depression intestinal inflammatory constipation. In this review, we re-examine interaction mechanisms between its associated explore new strategies for promoting human health combating diseases through di-etary interventions.

Язык: Английский

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