Bioconvection in Microalgae: Review of Mathematical Models
Laura Barsanti,
Lorenzo Birindelli,
Angelo Di Garbo
и другие.
Applied Sciences,
Год журнала:
2025,
Номер
15(5), С. 2708 - 2708
Опубликована: Март 3, 2025
Bioconvection
can
be
defined
as
an
aggregation
pattern-generating
phenomenon
characterized
by
the
collective
behavior
of
swimming
microorganisms
in
response
to
external
influences
and
self-induced
fluid
flow,
it
has
attracted
significant
interest
study
microalgae.
This
review
aims
provide
a
comprehensive
examination
this
concentrated
population
suspended
microalgae
definable
nonlinear
dynamical
systems
(i.e.,
generators
spatial
temporal
patterns),
describing
clarifying
underlying
mechanisms,
ecological
implications,
possible
biotechnological
applications
different
fields
for
improvement
bioreactor
design
biomass
cultivation,
wastewater
treatment,
or
bioremediation.
The
most
influential
models
used
capture
complexity
bioconvection
are
perused
order
explore
intricate
interplay
internal
(biological,
physical,
environmental)
governing
pattern
formation
dynamics
alongside
recent
advancements
modeling
techniques
experimental
approaches.
Язык: Английский
The Microalgae <em>Chlamydomonas </em>for Bioremediation and Bioproduct Production
Опубликована: Июнь 3, 2024
The
extensive
metabolic
diversity
of
microalgae,
coupled
with
their
rapid
growth
rates
and
cost-effective
production,
position
these
organisms
as
highly
promising
resources
for
a
wide
range
biotechnological
applications.
These
characteristics
allow
microalgae
to
address
crucial
needs
in
both
the
agricultural,
medical,
industrial
sectors.
Microalgae
are
proving
be
val-uable
various
fields,
including
remediation
diverse
wastewater
types,
production
biofuels
biofertilizers,
extraction
products
from
biomass.
For
decades,
microalga
Chlamydomonas
has
been
widely
used
fundamental
research
model
organism
areas
such
photosynthesis,
respiration,
sulfur
phosphorus
metabolism,
nitrogen
flagella
synthesis,
among
others.
However,
recent
years,
potential
tool
bioremediation,
biofertilization,
biomass,
bio-products
increasingly
recognized.
Bioremediation
using
presents
significant
sustainable
reduction
contaminants
fa-cilitates
resource
recovery
valorization
microalgal
offering
important
economic
benefits.
also
established
itself
platform
va-riety
biotechnologically
interesting
products,
different
types
biofuels,
high-value-added
products.
aim
this
review
is
achieve
comprehensive
understanding
aspects,
explore
interrelationship,
which
would
offer
environmental
advantages.
Язык: Английский
Applications of the Microalgae Chlamydomonas and Its Bacterial Consortia in Detoxification and Bioproduction
Life,
Год журнала:
2024,
Номер
14(8), С. 940 - 940
Опубликована: Июль 27, 2024
The
wide
metabolic
diversity
of
microalgae,
their
fast
growth
rates,
and
low-cost
production
make
these
organisms
highly
promising
resources
for
a
variety
biotechnological
applications,
addressing
critical
needs
in
industry,
agriculture,
medicine.
use
microalgae
consortia
with
bacteria
is
proving
valuable
several
areas
biotechnology,
including
the
treatment
various
types
wastewater,
biofertilizers,
extraction
products
from
biomass.
monoculture
microalga
Chlamydomonas
has
been
prominent
research
model
many
years
extensively
used
study
photosynthesis,
sulphur
phosphorus
metabolism,
nitrogen
respiration,
flagellar
synthesis,
among
others.
Recent
increasingly
recognised
potential
Chlamydomonas-bacteria
as
tool
applications.
detoxification
wastewater
using
its
bacterial
offers
significant
sustainable
reduction
contaminants,
while
facilitating
resource
recovery
valorisation
microalgal
biofertilizers
can
offer
benefits,
such
increasing
crop
yields,
protecting
crops,
maintaining
soil
fertility
stability,
contributing
to
CO2
mitigation,
agricultural
practises.
Chlamydomonas-bacterial
play
an
important
role
high-value
products,
particularly
biofuels
enhancement
H2
production.
This
review
aims
provide
comprehensive
understanding
identify
current
applications
propose
new
development
directions
maximise
potential.
Язык: Английский
Bioremediation of Synthetic Wastewater with Contaminants of Emerging Concern by Nannochloropsis sp. and Lipid Production: A Circular Approach
Bioengineering,
Год журнала:
2025,
Номер
12(3), С. 246 - 246
Опубликована: Фев. 28, 2025
Contaminants
of
emerging
concern
(CECs)
pose
a
potential
risk
to
human
and
environmental
health.
Microalgae
bioremediation
is
promising
approach
for
transforming
or
removing
contaminants
from
the
environment,
while
contributing
circular
economy.
In
this
study,
Nannochloropsis
sp.
was
effectively
used
simultaneous
removal
six
CECs:
paracetamol,
ibuprofen,
imidacloprid,
methylparaben
bisphenol
A
at
10
µg
mL−1
triclosan
0.5
synthetic
wastewater,
which
were
able
survive
under
such
concentrations,
higher
than
those
commonly
found
in
environment
(up
2.82
methylparaben).
High
efficiencies
reached
(100%)
(93
±
2%),
paracetamol
30
1%,
64
2%
49
5%
removed,
respectively.
Subsequently,
lipids
extracted,
FAME
profile
characterised
using
GS-MS.
The
main
fatty
acids
identified
after
hexadecadienoic
acid
isomers
(C16:2),
palmitic
(C16),
linoleic
(C18:2)
γ-linolenic
(C18:3).
absence
oleic
stearic
noticed,
suggesting
an
alteration
lipidic
due
contaminant
exposure.
By
exploring
quantification
future
work,
applications
extracted
can
be
explored,
further
demonstrating
feasibility
process.
Язык: Английский
Enhancing Biomass and Lipid Production in Messastrum gracile Using Inorganic Carbon Substrates and Alternative Solvents for Lipid Extraction
Life,
Год журнала:
2025,
Номер
15(3), С. 407 - 407
Опубликована: Март 5, 2025
Microalgae
show
promise
as
a
biomass
and
bioproduct
for
applications
in
various
industries.
The
cultivation
of
microalgae
plays
crucial
role
optimizing
yield
accumulation.
provision
inorganic
carbon
substrates
substantially
enhances
microalgal
growth
lipid
biosynthesis,
resulting
marked
increases
the
production
biofuels
other
bioproducts.
This
study
examined
accumulation
Messastrum
gracile
IFRPD
1061
under
stress
conditions,
previously
unreported.
M.
was
subjected
to
varying
conditions
substrates,
1–3
g·L−1
sodium
carbonate
bicarbonate
concentration,
enhance
Optimal
productivity
levels
were
observed
with
addition
3
1
lipids,
productivities
392.64
53.57
mg·L−1·d−1,
respectively.
Results
underlined
effectiveness
sources
stimulating
enhancing
high-value
products.
extraction
lipids
from
freeze-dried
demonstrated
optimal
using
methanol/hexane
solvents
compared
control
experiments.
Lipid
yields
42.18%
46.81%
oven-dried
biomass,
Lipids
extracted
methanol/hexane/chloroform
indicated
potential
solvent
dry
an
ultrasonic-assisted
technique.
contributes
valuable
insights
into
maximizing
biofuel
microalgae,
highlighting
A.
gracilis
promising
candidate
industrial
applications.
Язык: Английский
Synthetic Biology Strategies and Tools to Modulate Photosynthesis in Microbes
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(7), С. 3116 - 3116
Опубликована: Март 28, 2025
The
utilization
of
photosynthetic
microbes,
such
as
cyanobacteria
and
microalgae,
offers
sustainable
solutions
to
addressing
global
resource
shortages
pollution.
While
these
microorganisms
have
demonstrated
significant
potential
in
biomanufacturing,
their
industrial
application
is
limited
by
suboptimal
efficiency.
Synthetic
biology
integrates
molecular
biology,
systems
engineering
principles
provide
a
powerful
tool
for
elucidating
mechanisms
rationally
optimizing
platforms.
This
review
summarizes
recent
advancements
regulating
photosynthesis
microalgae
via
synthetic
focusing
on
strategies
enhance
light
energy
absorption,
optimize
electron
transport
chains,
improve
carbon
assimilation.
Furthermore,
we
discuss
key
challenges
translating
genetic
modifications
large-scale
bioproduction,
highlighting
specific
bottlenecks
strain
stability,
metabolic
burden,
process
scalability.
Finally,
propose
solutions,
AI-assisted
engineering,
microbial
consortia,
next-generation
photobioreactor
designs,
overcome
limitations.
Overall,
while
holds
great
promise
enhancing
efficiency
further
research
needed
refine
develop
scalable
production
systems.
Язык: Английский
Insertional Mutagenesis as a Strategy to Open New Paths in Microalgal Molybdenum and Nitrate Homeostasis
Current Issues in Molecular Biology,
Год журнала:
2025,
Номер
47(6), С. 396 - 396
Опубликована: Май 26, 2025
Molybdenum
(Mo)
is
a
vital
micronutrient
for
nearly
all
living
organisms,
serving
as
cofactor
molybdoenzymes
that
catalyze
essential
redox
reactions
in
nitrogen
metabolism.
Among
these
enzymes,
nitrate
reductase
plays
crucial
role
assimilation.
Maintaining
Mo
homeostasis—including
uptake,
storage,
and
utilization—is
critical
to
avoid
both
deficiency
toxicity.
Our
research
focuses
on
uncovering
novel
molecular
components
involved
homeostasis,
particularly
connection
with
assimilation,
using
Chlamydomonas
reinhardtii,
model
green
microalga.
To
achieve
this,
we
generated
more
than
5000
transformants
through
insertional
mutagenesis
paromomycin
resistance
cassette
(AphVIII)
screened
them
altered
growth
under
different
concentrations.
We
identified
four
strains
showing
patterns
when
source
or
exhibiting
increased
sensitivity
Mo.
The
genomic
alterations
were
identified.
Notably,
Mo-resistant
Mo-sensitive
transformant
had
disruptions
the
genes
encoded
ABC-type
transport
proteins,
indicating
potential
proteins
transport.
Additionally,
two
unable
grow
nitrate.
One
of
mutation
CNX7,
gene
biosynthesis,
while
other
BAT1,
an
amino
acid
transporter.
BAT1
mutant
represents
interesting
case
study,
this
has
not
previously
been
associated
These
findings
enhance
our
understanding
homeostasis
mechanisms
open
new
paths
engineering
microalgae
improved
Язык: Английский
Characterizing A21: Natural Cyanobacteria-Based Consortium with Potential for Steroid Bioremediation in Wastewater Treatment
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(23), С. 13018 - 13018
Опубликована: Дек. 4, 2024
Microalga-bacteria
consortia
are
increasingly
recognized
for
their
effectiveness
in
wastewater
treatment,
leveraging
the
metabolic
synergy
between
microalgae
and
bacteria
to
enhance
nutrient
removal
overall
treatment
efficiency.
These
systems
offer
a
sustainable
approach
addressing
pollutants
such
as
nitrogen
phosphorus.
However,
potential
removing
specific
contaminants
like
steroid
hormones
is
less
explored.
In
this
study,
natural
microbial
consortium,
A21,
has
been
characterized
isolated
from
primary
sewage
Madrid
its
bioremediation
of
hormone
effluents
evaluated.
The
A21
consortium
includes
Alphaproteobacteria
genera
Язык: Английский