Опубликована: Июль 15, 2024
Anderson-Fabry disease (AFD) results from decreased enzyme activity of lyzosmal and intralyzosomal storage its nonhydrolyzed. Cadiovascular complications, mainly in s form HCM contribute substantially for AFD-patient’s mortality. Here we report three new cases obstructive (HOCM) due to unclassical presentation AFD isolated cardiac involvement. In all the diagnosis was made postoperative by routine genetic morphological testing. Together with previously published this illustrates potential safely beneficial effect septal surgical myectomy patients AFD-HOCM, as well underlines need more thorough screening clinical signs AFD-associated cardiomyopathy GLA variants among HOCM.
Язык: Английский