Emerging Arboviral Diseases in Pakistan: Epidemiology and Public Health Implications
M Ben Ammar,
Muhammad Moaaz,
Chaoxiong Yue
и другие.
Viruses,
Год журнала:
2025,
Номер
17(2), С. 232 - 232
Опубликована: Фев. 7, 2025
Arboviruses
pose
significant
public
health
challenges
globally,
particularly
in
Pakistan,
where
deforestation,
climate
change,
urbanization,
inadequate
sanitation,
and
natural
disasters
have
all
contributed
to
the
spread
of
mosquito-borne
flavivirus
diseases
like
dengue
fever.
The
lack
a
thorough
national
surveillance
system
has
made
it
difficult
determine
extent
distribution
these
diseases.
Concern
been
raised
by
recent
outbreaks
West
Nile
virus
(WNV)
chikungunya
(CHIKV)
epidemics,
which
may
lead
Zika
(ZIKV)
future.
Additionally,
hospital-based
detected
Japanese
encephalitis
(JEV)
region.
Evidence
also
points
presence
additional
arboviruses
healthy
populations,
such
as
Karshi
(KSV),
Tamdy
(TAMV),
Crimean–Congo
hemorrhagic
fever
(CCHFV),
severe
with
thrombocytopenia
syndrome
(SFTSV).
This
review
aims
address
risk
factors
linked
diseases,
provide
specific
policy
recommendations
for
efficient
disease
prevention
control,
describe
epidemiological
trends
Pakistan
while
emphasizing
critical
need
improved
investigations.
Язык: Английский
Advancements in Antibacterial Therapy: Feature Papers
Microorganisms,
Год журнала:
2025,
Номер
13(3), С. 557 - 557
Опубликована: Март 1, 2025
Antimicrobial
resistance
(AMR)
is
a
growing
global
health
crisis
that
threatens
the
efficacy
of
antibiotics
and
modern
medical
interventions.
The
emergence
multidrug-resistant
(MDR)
pathogens,
exacerbated
by
misuse
in
healthcare
agriculture,
underscores
urgent
need
for
innovative
solutions.
(1)
Background:
AMR
arises
from
complex
interactions
between
human,
animal,
environmental
health,
further
aggravated
overuse
inadequate
regulation
antibiotics.
Conventional
treatments
are
increasingly
ineffective,
necessitating
alternative
strategies.
Emerging
approaches,
including
bacteriophage
therapy,
antimicrobial
peptides
(AMPs),
nanotechnology,
microbial
extracellular
vesicles
(EVs),
CRISPR-based
antimicrobials,
provide
novel
mechanisms
complement
traditional
combating
resistant
pathogens.
(2)
Methods:
This
review
critically
analyzes
advanced
antibacterial
strategies
conjunction
with
systemic
reforms
such
as
stewardship
programs,
One
Health
framework,
surveillance
tools.
These
methods
can
enhance
detection,
guide
interventions,
promote
sustainable
practices.
Additionally,
economic,
logistical,
regulatory
challenges
impeding
their
implementation
evaluated.
(3)
Results:
technologies,
CRISPR
exhibit
promising
potential
targeting
mechanisms.
However,
disparities
resource
distribution
barriers
hinder
widespread
adoption.
Public–private
partnerships
agriculture
practices
critical
to
overcoming
these
obstacles.
(4)
Conclusions:
A
holistic
integrated
approach
essential
mitigating
impact
AMR.
By
aligning
therapeutic
policies,
fostering
interdisciplinary
collaboration,
ensuring
equitable
distribution,
we
develop
response
this
21st-century
challenge.
Язык: Английский
Holistic Approaches to Zoonoses: Integrating Public Health, Policy, and One Health in a Dynamic Global Context
Zoonotic Diseases,
Год журнала:
2025,
Номер
5(1), С. 5 - 5
Опубликована: Март 6, 2025
Zoonotic
diseases
pose
a
significant
global
health
threat,
driven
by
factors
such
as
globalization,
climate
change,
urbanization,
antimicrobial
resistance
(AMR),
and
intensified
human–animal
interactions.
The
increasing
interconnectedness
of
human,
animal,
environmental
underscores
the
importance
OH
paradigm
in
addressing
zoonotic
threats
globalized
world.
This
review
explores
complex
epidemiology
diseases,
challenges
associated
with
their
management,
necessity
for
cross-sector
collaboration
to
enhance
prevention
control
efforts.
Key
public
strategies,
including
surveillance
systems,
infection
measures,
community
education
programs,
play
crucial
roles
mitigating
outbreaks.
However,
gaps
governance,
resource
allocation,
interdisciplinary
cooperation
hinder
effective
disease
particularly
low-
middle-income
countries
(LMICs).
To
illustrate
effectiveness
approach,
this
highlights
successful
PREDICT
project,
Rwanda’s
National
One
Health
Program,
EcoHealth
Alliance,
Rabies
Elimination
Program
Philippines.
These
initiatives
demonstrate
how
integrating
efforts
can
early
detection,
improve
outbreak
responses,
reduce
burdens.
Strengthening
enhancing
infrastructure,
regulating
use,
investing
research
technological
innovations
are
essential
steps
toward
risks.
Ultimately,
coordinated,
multidisciplinary
approach
is
vital
dynamic
posed
ensuring
security
an
increasingly
interconnected
Язык: Английский
One Health Ethics and the Ethics of Zoonoses: A Silent Call for Global Action
Опубликована: Авг. 12, 2024
This
paper
presents
a
critical
review
of
key
issues
related
to
the
emergence
new
networks
for
spread
zoonotic
diseases
amid
mass
extinction
species.
Zoonotic
and
infectious
account
approximately
70%
existing
affecting
humans
animals.
The
initial
section
argues
that
term
"zoonoses"
should
not
be
confined
single-cause
events
within
veterinary
medicine.
Instead,
zoonoses
viewed
as
complex,
systemic
phenomena
shaped
by
interrelated
factors,
including
environmental,
sociocultural,
economic
elements,
influenced
anthropogenic
climate
change.
second
bioethical
principles
potential
strategies
those
engaged
in
disease
prevention.
third
uses
slaughter
animals
disaster
settings
case
study
illustrate
need
further
clarification
normative
interspecies
justice
conflicts
One
Health
ethics.
concludes
with
an
outlook
on
"zoonoethics."
Section
four
develops
analysis
interlinked
elements
trigger
examines
antimicrobial
resistance
(AMR)
from
ethical
political
standpoint,
concluding
policy
recommendations
addressing
AMR.
five
offers
reflection,
integrating
contributions
zoonoethics,
human
ecology,
ecotheological
turn.
Finally,
six
call
action
inclusive,
intercultural,
gender-sensitive
approach.
Язык: Английский