A Novel Wild-Type Lacticaseibacillus paracasei Strain Suitable for the Production of Functional Yoghurt and Ayran Products
Fermentation,
Год журнала:
2025,
Номер
11(1), С. 37 - 37
Опубликована: Янв. 17, 2025
Raw
goat
and
ewe’s
milk
samples
were
used
for
the
isolation
of
seven
lactic
acid
bacteria
new
strains.
After
testing
hemolytic
activity
resistance
to
antibiotics,
specific
functional
properties
evaluated;
Lactococcus
lactis
subsp.
FBM_1321
Lacticaseibacillus
paracasei
FBM_1327
strains
resulted
in
highest
cholesterol
assimilation
percentages
ranging
from
28.78
30.56%.
In
addition,
strong
adhesion
capacity
differentiated
Caco-2
cells
(1.77–21.04%)
was
mapped,
lactobacilli
exhibited
antagonistic
against
foodborne
pathogens
compared
lactococci.
The
able
grow
at
low
pH
high
NaCl
concentrations,
conditions
that
prevail
food
systems
(cell
counts
ranged
1.77
8.48
log
CFU/mL
after
exposure
3
5.66
9.52
concentrations
up
8%).
As
a
next
step,
freeze-dried
immobilized
Lc.
on
oat
flakes
preparation
yoghurt
ayran
products.
Cell
loads
strain
remained
stable
both
products
(7.69
CFU/g
8.56
30
days
storage
4
°C)
throughout
their
shelf
life.
No
significant
changes
volatile
profile
noticed,
accepted
by
panel
during
sensory
evaluation.
Язык: Английский
Effects of Free or Immobilized Pediococcus acidilactici ORE5 on Corinthian Currants on Gut Microbiome of Streptozotocin-Induced Diabetic Rat
Опубликована: Авг. 20, 2024
Type-1
Diabetes
Mellitus
(T1D)
onset
and
development
is
closely
linked
with
imbalance
of
gut
microbiome,
while
supplementation
probiotics
may
result
in
positive
alterations
microbiome
composition.
In
the
present
study,
effect
a
dietary
intervention
including
free
or
immobilized
cells
presumptive
probiotic
Pediococcus
acidilactici
ORE5
on
Corinthian
currants,
food
beneficial
impact
condition
diabetes,
was
investigated.
Male
Wistar
rats
were
studied
which
divided
into
4
groups:
healthy
animals,
received
(H_FP)
(H_IPC),
diabetic
(D_FP)
(D_IPC),
for
weeks
(109
cfu/day,
all
groups).
At
end
intervention,
D_IPC
group
exerted
lower
concentration
inflammatory
cytokine
IL-1b
compared
to
D_FP.
Consumption
currants
P.
by
animals
led
increased
loads
fecal
lactobacilli
levels
Enterobacteriaceae,
coliforms,
E.
coli,
Actinobacteria
phylum,
Akkermansia,
Bifidobacterium
genera
abundances
increased,
lactic
acid
elevated.
Overall,
results
research
demonstrated
that
functional
ingredients
can
ameliorate
dysbiosis
T1D
could
be
used
design
patterns
aiming
at
management.
However,
well-designed
clinical
trials
are
necessary,
order
confirm
effects
humans.
Язык: Английский
Assessment of Immobilized Lacticaseibacillus rhamnosus OLXAL-1 Cells on Oat Flakes for Functional Regulation of the Intestinal Microbiome in a Type-1 Diabetic Animal Model
Foods,
Год журнала:
2024,
Номер
13(24), С. 4134 - 4134
Опубликована: Дек. 20, 2024
The
aim
of
this
study
was
to
examine
the
effect
free
or
immobilized
Lacticaseibacillus
rhamnosus
OLXAL-1
cells
on
oat
flakes
gut
microbiota
and
metabolic
inflammatory
markers
in
a
streptozotocin
(STZ)-induced
Type-1
Diabetes
Mellitus
(T1DM)
animal
model.
Forty-eight
male
Wistar
rats
were
assigned
into
eight
groups
(n
=
6):
healthy
diabetic
animals
that
received
either
control
diet
(CD
DCD),
an
oat-supplemented
(OD
DOD),
supplemented
with
L.
(CFC
DFC),
(CIC
DIC).
Neither
nor
supplementation
led
any
significant
positive
effects
body
weight,
insulin
levels,
plasma
glucose
concentrations,
lipid
profile
parameters.
administration
resulted
rise
relative
abundances
Lactobacillus
Bifidobacterium,
as
well
increased
levels
lactic,
acetic,
butyric
acids
feces
animals.
Additionally,
significantly
reduced
microbial
populations
E.
coli,
Enterobacteriaceae,
coliforms,
staphylococci,
enterococci
lowered
IL-1β
blood
These
findings
suggested
probiotic
food-based
strategies
could
have
potential
therapeutic
role
managing
dysbiosis
inflammation
associated
T1DM.
Язык: Английский