Опубликована: Авг. 21, 2024
Simple Summary (148 words) There is increasing evidence, that cannabinoids may play an important and dual role in tumour therapy. On one hand, they are cytotoxic against cancer cells with a low toxicity normal, healthy tissues, on the other, reduce typical side effects of chemotherapy. Publications main motive for use cannabis (cannabinoids) by patients show patients' expectations exceed scientific facts. This article briefly describes results combinations standard antineoplastic drugs tumours Although observations still limited to animal studies very few experiences patients, preliminary data suggest adjuvant improve survival glioblastoma perhaps other tumours. Benefits have also been reported about chemotherapy-induced nausea vomiting, peripheral neuropathic pain, loss appetite anxiety. promising, much more research necessary. Abstract (192 Cancer, leading causes death worldwide, rise. The high conventional chemotherapy, often applied as drug cocktails, resistance development limits anti-neoplastic reduces quality life. With easier access, growing number using alleviation their symptoms, hope improving survival. narrative summarizes observed phytocannabinoids chemotherapeutic agents models patients. Preliminary combined exert increased anti-cancer actions, Respective scarce concern small numbers glioblastoma, pancreatic carcinoma. Further benefits (dronabinol), pain anxiety (cannabidiol). In addition, phytocannabinoids, particular cannabidiol, protection organs such heart, lung or kidney toxicity. needed determine whether positive outweigh eventual risks.
Язык: Английский