Minority stress in relation to biological outcomes among sexual and gender minority people: a systematic review and update

Journal of Behavioral Medicine, Год журнала: 2025, Номер unknown

Опубликована: Янв. 9, 2025

Язык: Английский

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Aging-Related Comorbidity Burden Among Women and Men With or At-Risk for HIV in the US, 2008-2019

JAMA Network Open, Год журнала: 2023, Номер 6(8), С. e2327584 - e2327584

Опубликована: Авг. 7, 2023

Importance Despite aging-related comorbidities representing a growing threat to quality-of-life and mortality among persons with HIV (PWH), clinical guidance for comorbidity screening prevention is lacking. Understanding distribution severity by sex gender essential informing guidelines promoting healthy aging in adults HIV. Objective To assess the association of human immunodeficiency virus on burden US modern treatment era. Design, Setting, Participants This cross-sectional analysis included data from multisite observational cohort studies women (Women’s Interagency Study) men (Multicenter AIDS Cohort sociodemographically comparable HIV-seronegative individuals. were prospectively followed 2008 2009 (when more than 80% participants reported antiretroviral therapy use) through last observation up until March 2019, at which point outcomes assessed. Data analyzed July 2020 April 2021. Exposures HIV, age, sex. Main Outcomes Measures Comorbidity (the number total out 10 assessed) per participant; secondary individual prevalence. Linear regression assessed status, burden. Results A 5929 individuals (median [IQR] 54 [46-61] years; 3238 [55%]; 2787 Black [47%], 1153 Hispanic or other [19%], 1989 White [34%]). Overall, unadjusted mean was higher vs (3.4 [2.1] 3.2 [1.8]; P = .02). prevalence differed hypertension (2188 [68%] 2026 2691 [75%]), psychiatric illness (1771 [55%] 1565 [58%]), dyslipidemia (1312 [41%] 1728 [64%]), liver (1093 [34%] 1032 [38%]), bone disease (1364 [42%] 512 [19%]), lung (1245 [38%] 259 [10%]), diabetes (763 [24%] 470 [17%]), cardiovascular (493 [15%] 407 [15%]), kidney (444 [14%] 404 [15%]) disease, cancer (219 [7%] 321 [12%]). In an model, estimated difference significantly greater every age strata PWH: under 40 years, 0.33 (95% CI, 0.03-0.63); ages 49 0.37 0.12-0.61); 50 59 0.38 0.20-0.56); 60 69 0.66 0.42-0.90); 70 years older, 0.62 0.07-1.17). However, between sexes varied without HIV: 0.52 0.13 0.92); −0.07 −0.45 0.31); 0.88 1.14); 1.39 1.06 1.72); −0.53 1.19) ( interaction .001). covariate-adjusted findings slightly attenuated but retained statistical significance. Conclusions Relevance this study, overall men, particularly PWH, strategies tailored serostatus may be needed.

Язык: Английский

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Influence of Experiences of Discrimination and Anticipated Discrimination on Cardiovascular Health Outcomes

Current Cardiology Reports, Год журнала: 2025, Номер 27(1)

Опубликована: Фев. 7, 2025

Язык: Английский

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The Changing Needs of Peer Support Among Gay Men Living with HIV in Australia: A Reflexive Thematic Analysis

Archives of Sexual Behavior, Год журнала: 2025, Номер unknown

Опубликована: Фев. 11, 2025

Язык: Английский

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A systematic review of mediation analysis frameworks in studies examining the determinants of cardiometabolic outcomes in people living with HIV

BMC Medical Research Methodology, Год журнала: 2025, Номер 25(1)

Опубликована: Фев. 20, 2025

Mediation analysis provides a more flexible mechanistic view of the causal relationship between HIV-related factors and cardiometabolic diseases. However, there is limited evidence on how mediation implemented in this specific research area. We aimed to describe frameworks used examine these analyses are conducted reported studies focusing outcomes among people living with HIV (PLWH). Following PRISMA 2020 Guidelines, we comprehensively searched Medline, CINAHL, Africa-Wide Information SCOPUS identify observational that employed before October 2023. Two reviewers independently screened for eligibility. One reviewer performed data extraction, two others reviewed extracted information. Nine met inclusion criteria, predominantly effects weight obesity-related serostatus, ART, outcomes. The review revealed diverse application both traditional frameworks. inconsistencies gaps reporting were noted, particularly handling missing data, detailing identifiability assumptions, use sensitivity analyses. While some risks PLWH have embraced frameworks, their overall remains limited. In addition, identified notable practices. To advance field, researchers should not only integrate rigorous methods but also closely follow established guidelines, such as AGReMA Statement, ensure greater transparency, reliability, impact future research.

Язык: Английский

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The Intersectional Influence of Experienced Stigma on Clinically Significant Depressive Symptoms Among Gay, Bisexual, and Other Men Who Have Sex with Men

Journal of Homosexuality, Год журнала: 2025, Номер unknown, С. 1 - 26

Опубликована: Март 5, 2025

We sought to determine how intersectional stigma, operationalized by interactions of perceived stigma experiences in adulthood attributed various social identities/characteristics (age, gender, race, ethnicity/nationality, religion, height/weight, other aspect appearance [unrelated the listed-e.g. height/weight/race/gender], physical disability, sexual orientation, and HIV status), associates with clinically significant depressive symptoms (DS). used data from Multicenter AIDS Cohort Study (Baltimore/Washington, DC; Chicago; Pittsburgh/Columbus; Los Angeles) on 1,385 minority men (SMM), collected April 1, 2008-March 31, 2009. Classification trees predicted DS. An exploratory factor analysis (EFA) identified stigmas that tended co-occur. calculated decomposed joint disparity DS risk between comprising each EFA factor. Thirty-four percent were classified Stigma was most commonly orientation. Participants multiple had an increased In classification trees, covariates (especially income) stronger predictors than stigmas. Intersectional effects observed disability (positive effect), race ethnicity/nationality orientation status (negative effects). Interventions reduce among SMM, as well improve socioeconomic position SMM general, are needed.

Язык: Английский

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Mapping the AIDS Week Health Campaign on Social Media in China: A Mixed-Method Study

Health Communication, Год журнала: 2024, Номер unknown, С. 1 - 17

Опубликована: Дек. 13, 2024

This study aimed to explore the dissemination of HIV/AIDS-related information and risk factors on social media during AIDS Weeks, helping policymakers public health organizations understand how utilizes formulate strategies for campaigns better. used Latent Dirichlet Allocation (LDA) topic modeling sentiment analysis investigate distribution themes people's reactions Weeks. Additionally, Critical Discourse Analysis (CDA) was employed further examine structures, cultural contexts, power dynamics underlying discourse. From 2018 2021, 48437 posts were analyzed, revealing 21 topics coded categorized into six main themes: Response Methods, Specific Topics, Promotion, Virus Status, Groups, Positive Feedback. discourse uncovered a parallel trend demonstrating both threat efficacy in Week promotion China. However, lack actionable prevention may reduce behavioral intentions. The top-down implementation approach ensures efficient execution at all levels but also results formalism Week. Text vary annually based slogans requiring localization effective overcoming barriers detrimental promotion. Cultural context structures contribute issues such as stigmatization marginalized groups. We suggest enhancing user engagement interaction through platforms activities. Collaboration between companies can increase awareness disease, mitigate societal biases, provide accurate practical guidance.

Язык: Английский

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Intersectionality in nursing research: A scoping review

International Journal of Nursing Studies Advances, Год журнала: 2023, Номер 5, С. 100155 - 100155

Опубликована: Сен. 30, 2023

An intersectional approach to health research provides an analytical foundation explain the multidimensionality of status, resource accessibility, privilege, oppression, and current historical context. The use intersectionality in has known limitations. Its health-related fields too often focuses on outcomes, such as disparities, rather than processes, power structures social determinants. This scoping review serves examine how been implemented by nurses peer-reviewed literature. We offer insight into it may be incorporated inform future nursing healthcare provision. Systematic searches PubMed (n=257), SCOPUS (n=807), EMBASE (n=396), CINAHL (n=224), Health Source: Nursing Academics (n=491), published since seminal publication (1989 - 2023), identified 131 articles that met inclusion exclusion criteria. Data extraction synthesis were used describe breadth depth literature specific application research. included studies intersections numerous identities, race, gender, immigration status. However, most descriptive/observational nature, underreported their methods, conducted deficit-based instead strength-based inquiries. Of note, vast majority within last five years. Future researchers using a framework can improve reporting clear definitions operationalization intersectionality. Observational science dominated studies; should focus intervention development evaluation lens. Lastly, caution placed solely deficits among marginalized communities, which places scientists at risk perpetuating stereotypes or enhancing already-existing stigmas. Scoping revealed have applied globally, pointing its growing role advancement equity. @emorynursing @athenashermanrn @sfcphdrn

Язык: Английский

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Intersecting Stigma and the HIV Care Cascade: Qualitative Insights from Sex Workers, Men who have Sex with Men, and Transgender Women Living with HIV in Jamaica

AIDS and Behavior, Год журнала: 2024, Номер 28(11), С. 3768 - 3786

Опубликована: Авг. 5, 2024

Язык: Английский

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Intersectional stigma and the non-communicable disease syndemic in the context of HIV: protocol for a multisite, observational study in the USA

BMJ Open, Год журнала: 2024, Номер 14(4), С. e075368 - e075368

Опубликована: Апрель 1, 2024

Introduction The increasing burden of non-communicable diseases, such as hypertension, diabetes and dyslipidaemia, presents key challenges to achieving optimal HIV care outcomes among ageing people living with HIV. These diseases are often comorbid exacerbated by psychosocial structural inequities. This interaction multiple health conditions social factors is referred a syndemic. In the USA, there substantial disparities position (ie, racial, ethnic socioeconomic status) in prevalence and/or control Intersecting stigmas, racism, classism homophobia, may drive these contributing healthcare avoidance syndemic (stress, depression, violence victimisation substance use), reducing success along disease continua care. Our hypothesis that marginalised populations experience incidence, control, mediated intersectional stigma Methods analysis Collecting data over 4 year period, we will recruit sexual minority men (planned n=1800) enrolled MACS/WIHS Combined Cohort Study, long-standing mixed-serostatus observational cohort investigate following specific aims: (1) assess relationships between position, middle-aged men, (2) incidence (3) outcomes, Analyses be conducted using generalised equation models cross-lagged panel model design. Ethics dissemination protocol approved single-IRB study (Advarra Institutional Review Board: Protocol 00068335). We disseminate results via peer-reviewed academic journals, scientific conferences, dedicated website, site community advisory boards forums hosted at participating sites.

Язык: Английский

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