Advances in Therapeutic Contact Lenses for Different Ocular Condition Management DOI Open Access
Mariana Ioniță,

George Mihai Vlăsceanu,

Georgian Alin Toader

и другие.

Опубликована: Окт. 1, 2023

The number of people affected by eye conditions is growing every year, due to the popularity electronic devices and an aging population. In world medicine, accomplishing medication administration has always been a difficult task. Despite fact that there are many drops on market, most them have important limitations quick clearance mechanisms ocular barriers. One solution with tremendous potential contact lens used as delivery vehicle bypass this constraint. Therapeutic lenses for attracted lot attention because they improve bioavailability, patient compliance, reduce side effects. However, it essential not compromise features such water content, optical transparency, modulus in order target successful vitro vivo sustained drug profile from impregnated lenses. Aside difficulties like stability burst release, changing physical chemical properties caused therapeutic or non-therapeutic components can limit commercialization pharmaceutical-loaded Research progressed towards bioinspired techniques smart materials efficacy drug-eluting method uses polymeric biocompatibility, specialized molecule recognition technique called molecular imprinting, stimuli-responsive system biocompatibility support This review encompasses strategies material design, manufacturing impregnation under current auspices ophthalmic therapies projects outlook onto future opportunities field management means active principles-eluting lens.

Язык: Английский

Advances in Therapeutic Contact Lenses for the Management of Different Ocular Conditions DOI Open Access
Mariana Ioniță, George Mihail Vlăsceanu,

Alin Georgian Toader

и другие.

Journal of Personalized Medicine, Год журнала: 2023, Номер 13(11), С. 1571 - 1571

Опубликована: Ноя. 3, 2023

In the advent of an increasingly aging population and due to popularity electronic devices, ocular conditions have become more prevalent. world medicine, accomplishing eye medication administration has always been a difficult task. Despite fact that there are many commercial drops, most them important limitations, quick clearance mechanisms barrers. One solution with tremendous potential is contact lens used as delivery vehicle bypass this constraint. Therapeutic lenses for attracted lot attention because they improve bioavailability patient compliance, both minimal side effects. However, it essential not compromise features such water content, optical transparency, modulus attain positive in vitro vivo outcomes respect sustained drug profile from impregnated lenses. Aside difficulties like stability burst release, changing physico-chemical caused by therapeutic or non-therapeutic components can limit commercialization pharmaceutical-loaded Research progressed towards bioinspired techniques smart materials, efficacy drug-eluting The method uses polymeric specialized molecule-recognition technique called molecular imprinting stimuli-responsive system biocompatibility support This review encompasses strategies material design, manufacturing impregnation under current auspices ophthalmic therapies projects outlook onto future opportunities field condition management means active principle-eluting lens.

Язык: Английский

Процитировано

9
Advances in Therapeutic Contact Lenses for Different Ocular Condition Management DOI Open Access
Mariana Ioniță,

George Mihai Vlăsceanu,

Georgian Alin Toader

и другие.

Опубликована: Окт. 1, 2023

The number of people affected by eye conditions is growing every year, due to the popularity electronic devices and an aging population. In world medicine, accomplishing medication administration has always been a difficult task. Despite fact that there are many drops on market, most them have important limitations quick clearance mechanisms ocular barriers. One solution with tremendous potential contact lens used as delivery vehicle bypass this constraint. Therapeutic lenses for attracted lot attention because they improve bioavailability, patient compliance, reduce side effects. However, it essential not compromise features such water content, optical transparency, modulus in order target successful vitro vivo sustained drug profile from impregnated lenses. Aside difficulties like stability burst release, changing physical chemical properties caused therapeutic or non-therapeutic components can limit commercialization pharmaceutical-loaded Research progressed towards bioinspired techniques smart materials efficacy drug-eluting method uses polymeric biocompatibility, specialized molecule recognition technique called molecular imprinting, stimuli-responsive system biocompatibility support This review encompasses strategies material design, manufacturing impregnation under current auspices ophthalmic therapies projects outlook onto future opportunities field management means active principles-eluting lens.

Язык: Английский

Процитировано

1