Emerging Trends in Bioinspired Superhydrophobic and Superoleophobic Sustainable Surfaces

Advanced Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 18, 2025

Abstract Inspired by nature's ability to master materials for performance and sustainability, biomimicry has enabled the creation of bioinspired structural color, superadhesion, hydrophobicity hydrophilicity, among many others. This review summarizes emerging trends in novel sustainable fluorocarbon‐free designs creating superhydrophobic superoleophobic surfaces. It discusses methods, challenges, future directions, alongside impact computational modeling artificial intelligence accelerating experimental development more surface materials. While significant progress is made materials, surfaces remain a challenge. However, bioinspiration techniques supported platforms are paving way new renewable biodegradable repellent that meet environmental standards without sacrificing performance. Nevertheless, despite concerns, policies, several still continue apply fluorination other environmentally harmful achieve required standard repellency. As discussed this critical review, paradigm integrates advanced characterization, nanotechnology, additive manufacturing, modeling, coming, generate with tailored superhydrophobicity superoleophobicity while adhering standards.

Язык: Английский

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Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review

Mini-Reviews in Medicinal Chemistry, Год журнала: 2024, Номер 24(13), С. 1238 - 1251

Опубликована: Янв. 8, 2024

Heterocyclic compounds and their derivatives play a significant role in the design development of novel quinoline drugs. Among various pharmacologically active heterocyclic compounds, quinolines stand out as most rings due to broad pharmacological roles, specifically antitubercular activity, presence plant-based compounds. Quinoline is also known benzpyridine, benzopyridine, 1-azanaphthalene. It has benzene ring fused with pyridine ring, both share two carbon atoms. The importance lies its incorporation key component natural found medicinal plant families like

Язык: Английский

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What is the plausibility that all drugs will be designed by computers by the end of the decade?

Expert Opinion on Drug Discovery, Год журнала: 2024, Номер 19(5), С. 507 - 510

Опубликована: Март 19, 2024

KEYWORDS: Artificial intelligenceautomatizationcomputer-aided drug designcomputationally driven discoveryde novodrug discoveryeducationin silico design

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Ion Channel and Transporter Involvement in Chemotherapy-Induced Peripheral Neurotoxicity

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(12), С. 6552 - 6552

Опубликована: Июнь 14, 2024

The peripheral nervous system can encounter alterations due to exposure some of the most commonly used anticancer drugs (platinum drugs, taxanes, vinca alkaloids, proteasome inhibitors, thalidomide), so-called chemotherapy-induced neurotoxicity (CIPN). CIPN be long-lasting or even permanent, and it is detrimental for quality life cancer survivors, being associated with persistent disturbances such as sensory loss neuropathic pain at limb extremities a mostly axonal polyneuropathy/neuronopathy. In state art, there no efficacious preventive/curative treatment this condition. Among reasons unmet clinical scientific need, an uncomplete knowledge pathogenetic mechanisms. Ion channels transporters are pivotal elements in both central system, growing body literature suggesting that they might play role development. review, we first describe biophysical properties these targets then report existing data involvement ion CIPN, thus paving way new approaches/druggable cure and/or prevent CIPN.

Язык: Английский

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Spectroscopic and Quantum chemical studies of some novel mixed-ligand complexes of vanadium and Comparative evaluation of their antimicrobial and antioxidant activities

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 113967 - 113967

Опубликована: Янв. 1, 2025

Язык: Английский

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Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus

Computers in Biology and Medicine, Год журнала: 2025, Номер 186, С. 109727 - 109727

Опубликована: Янв. 25, 2025

Язык: Английский

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An insight into in silico strategies used for exploration of medicinal utilty and toxicology of Nanomaterials

Computational Biology and Chemistry, Год журнала: 2025, Номер unknown, С. 108435 - 108435

Опубликована: Март 1, 2025

Язык: Английский

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Computational Drug-Likeness Studies of Selected Thiosemicarbazones: A Sustainable Approach for Drug Designing

Опубликована: Апрель 2, 2025

Язык: Английский

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Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 28, 2025

Язык: Английский

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Biological Exploration of Theophylline-Appended Acetamides as Anti-SARS-CoV-2 Agents Targeting Main Protease (Mpro), Spike Glycoprotein and RNA-dependent RNA Polymerase (RdRp)

Journal of Molecular Structure, Год журнала: 2025, Номер unknown, С. 142858 - 142858

Опубликована: Июнь 1, 2025

Язык: Английский

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