The use of general anaesthesia in special care dentistry: A clinical guideline from the British Society for Disability and Oral Health DOI Creative Commons
Andrew Geddis‐Regan,

Deborah Gray,

Sarah Buckingham

и другие.

Special Care in Dentistry, Год журнала: 2022, Номер 42(S1), С. 3 - 32

Опубликована: Янв. 1, 2022

General anaesthesia (GA) may be required to support the care of those seen in Special Care Dentistry (SCD) services for various reasons, such as enabling extensive dental people with severe learning disabilities or phobia. Guidance is needed teams delivering SCD using GA due potential risks, implications, and costs deliver care.To present evidence-based recommendations, where possible, involved providing adults within services.A multidisciplinary working group, supported by a formal literature search stakeholder involvement, iteratively produced refined recommendations presented.There was little evidence inform guidelines. Recommendations are therefore based mainly on group's expert consensus opinion. Clinical guidelines presented set overarching principles followed six key sections reflecting patients' pathways from referral through their during after GA.Guidelines provide SCD. The need comprehensive person-centered assessment planning emphasized.

Язык: Английский

An update on the clinical consequences of polypharmacy in older adults: a narrative review DOI Open Access
Jonas W. Wastesson, Lucas Morin, Edwin C.K. Tan

и другие.

Expert Opinion on Drug Safety, Год журнала: 2018, Номер 17(12), С. 1185 - 1196

Опубликована: Дек. 2, 2018

Polypharmacy, the use of multiple medications by one individual, is increasingly common among older adults. Caring for growing number people with complex drug regimens and multimorbidity presents an important challenge in coming years.This article reviews international trends prevalence polypharmacy, summarizes results from previous on polypharmacy negative health outcomes, updates a review clinical consequences focusing studies published after 2013. This narrative review, which based literature search MEDLINE EMBASE January 1990 to June 2018, was undertaken identify relevant articles. Search terms included variations medications.The increasing worldwide. More than half population exposed some settings. Polypharmacy associated broad range consequences. However, methods assess dangers should be refined. In our opinion, issue 'confounding multimorbidity' has been underestimated better accounted future studies. Moreover, researchers develop more clinically definitions including measures inappropriate or problematic polypharmacy.

Язык: Английский

Процитировано

458

An overview of prevalence, determinants and health outcomes of polypharmacy DOI Creative Commons
Mina Khezrian, Christopher J. McNeil, Alison D. Murray

и другие.

Therapeutic Advances in Drug Safety, Год журнала: 2020, Номер 11

Опубликована: Янв. 1, 2020

A high rate of polypharmacy is, in part, a consequence the increasing proportion multimorbidity ageing population worldwide. Our understanding potential harm taking multiple medications an older, multi-morbid population, who are likely to be on regime, is limited. This narrative literature review that aims appraise and summarise recent studies published about polypharmacy. We searched MEDLINE using search terms (and its variations, e.g. prescriptions, inappropriate drug use, etc.) titles. Systematic reviews original English between 2003 2018 were included. In this review, we provide current definitions identify determinants prevalence reported different studies. Finally, some findings regarding association health outcomes older adults, with focus frailty, hospitalisation mortality. Polypharmacy was most often defined number being taken by individual at any given time. showed varied 10% as around 90% populations. Chronic conditions, demographics, socioeconomics self-assessed factors independent predictors associated various adverse after adjusting for conditions. Optimising care valid, reliable measures, relevant all patients, will improve adult population.

Язык: Английский

Процитировано

317

Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences DOI Creative Commons
Farhad Pazan,

Martin Wehling

European Geriatric Medicine, Год журнала: 2021, Номер 12(3), С. 443 - 452

Опубликована: Март 10, 2021

Abstract Background The number of older adults has been constantly growing around the globe. Consequently, multimorbidity and related polypharmacy have become an increasing problem. In absence accepted agreement on definition polypharmacy, data its prevalence in various studies are not easily comparable. Besides, evidence potential adverse clinical outcomes to is limited though linked numerous outcomes. This narrative review aims find summarize recent publications definitions, epidemiology consequences polypharmacy. Methods MEDLINE database was used identify definition, using their respective common terms variations. Systematic reviews original published between 2015 2020 were included. Results One hundred forty-three definitions associated found. Most them numerical definitions. Its ranges from 4% among community-dwelling people over 96.5% hospitalized patients. addition, with Conclusion term imprecise, yet subject ongoing debate. clinically oriented found this such as appropriate or necessary more useful relevant. Regardless highly prevalent adults, particularly nursing home residents Approaches increase appropriateness can improve adults.

Язык: Английский

Процитировано

276

The Healthy Microbiome—What Is the Definition of a Healthy Gut Microbiome? DOI
Fergus Shanahan, Tarini Shankar Ghosh, Paul W. O’Toole

и другие.

Gastroenterology, Год журнала: 2020, Номер 160(2), С. 483 - 494

Опубликована: Ноя. 27, 2020

Язык: Английский

Процитировано

263

Culture as a cure DOI Open Access

Katherine De Bienassis,

Solvejg Kristensen,

Magdalena Burtscher

и другие.

OECD health working papers, Год журнала: 2020, Номер unknown

Опубликована: Май 30, 2020

While health care quality has been improving on average in OECD members countries, patient safety remains a central priority for policy makers and leaders. A growing research body found that PSC is associated with numerous positive outcomes, including improved experience, organisational productivity staff satisfaction. Tools to measure have proliferated recent decades are now wide-spread use. This report includes findings from countries the state of art measurement practices related PSC. Overall, prevalent across though application, purpose, tools vary. International learning benchmarking significant potential better understanding improvement quality.

Язык: Английский

Процитировано

227

Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis DOI Creative Commons

Mahin Delara,

Lauren Murray,

Behnaz Jafari

и другие.

BMC Geriatrics, Год журнала: 2022, Номер 22(1)

Опубликована: Июль 19, 2022

Abstract Introduction Polypharmacy is commonly associated with adverse health outcomes. There are currently no meta-analyses of the prevalence polypharmacy or factors polypharmacy. We aimed to estimate pooled and in a systematic review meta-analysis. Methods MEDLINE, EMBASE, Cochrane databases were searched for studies restrictions on date. included observational that reported among individuals over age 19. Two reviewers extracted study characteristics including definitions, design, setting, geography, participant demographics. The risk bias was assessed using Newcastle-Ottawa Scales. main outcome prevalence. estimates 95% confidence intervals determined random effects Subgroup analyses undertaken evaluate such as design geography. Meta-regression conducted assess associations between year. Results 106 full-text articles identified. estimated 54 reporting all medication classes 37% (95% CI: 31-43%). Differences different numerical thresholds, publication Sex, geographical location not differences Discussion Our highlights common particularly older adults those inpatient settings. Clinicians should be aware populations who have an increased likelihood experiencing efforts made appropriateness prescribed medications occurrence potentially Conclusions implications undertake minimize inappropriate whenever possible.

Язык: Английский

Процитировано

182

Barriers and facilitators to deprescribing in primary care: a systematic review DOI Creative Commons
Alison Jayne Doherty, Paul Boland, Janet Reed

и другие.

BJGP Open, Год журнала: 2020, Номер 4(3), С. bjgpopen20X101096 - bjgpopen20X101096

Опубликована: Июль 28, 2020

Background Managing polypharmacy is a challenge for healthcare systems globally. It also health inequality concern as it can expose some of the most vulnerable in society to unnecessary medications and adverse drug-related events. Care patients with multimorbidity occurs primary care. Safe deprescribing interventions reduce exposure inappropriate polypharmacy. However, these are not fully accepted or routinely implemented. Aim To identify barriers facilitators safe adults Design & setting A systematic review studies published from 2000, examining Method search electronic databases: MEDLINE, Embase, Cumulative Index Nursing Allied Health Literature (CINHAL), Cochrane, Management Information Consortium (HMIC) inception 26 Feb 2019, using an agreed strategy. This was supplemented by handsearching relevant journals, screening reference lists citations included studies. Results In total, 40 14 countries were identified. Cultural organisational included: culture diagnosing prescribing; evidence-based guidance focused on single diseases; lack care older people multimorbidities; shared communication, decision-making systems, tools, resources. Interpersonal individual-level professional etiquette; fragmented care; prescribers’ patients’ uncertainties; gaps tailored support. Facilitators prudent greater availability acceptability non-pharmacological alternatives; resources; improved collaboration, knowledge, understanding; patient-centred decision-making. Conclusion whole approach required, involving key decision-makers, professionals, patients, carers.

Язык: Английский

Процитировано

157

The economics of medication safety DOI

Katherine De Bienassis,

Laura Esmail,

Ruth Lopert

и другие.

OECD health working papers, Год журнала: 2022, Номер unknown

Опубликована: Сен. 13, 2022

Poor medication practices and inadequate system infrastructure—resulting in poor adherence, medication-related harms, errors—too often results patient harm. As many as 1 10 hospitalizations OECD countries may be caused by a event one five inpatients experience harms during hospitalization. Together, costs from avoidable admissions due to events added length of stay preventable hospital-acquired total over USD 54 billion countries. This report includes four components; it 1) assess the human impact economic safety countries, 2) explores opportunities improve prescribing 3) examines state-of-the art systems policies for improving safety, 4) provides recommendations at national level.

Язык: Английский

Процитировано

137

Prevalence of multimorbidity and polypharmacy among adults and older adults: a systematic review DOI Creative Commons
Kathryn Nicholson, Winnie Liu, Daire W. D. Fitzpatrick

и другие.

The Lancet Healthy Longevity, Год журнала: 2024, Номер 5(4), С. e287 - e296

Опубликована: Март 4, 2024

Multimorbidity (multiple conditions) and polypharmacy medications) are increasingly common, yet there is a need to better understand the prevalence of co-occurrence. In this systematic review, we examined multimorbidity among adults (≥18 years) older (≥65 in clinical community settings. Six electronic databases were searched, 87 studies retained after two levels screening. Most focused on 65 years done population-based Although operational definitions varied across studies, consistent cut-points (two or more conditions five used most studies. adult samples, ranged from 4·8% 93·1%, while 2·6% 86·6%. High heterogeneity between indicates for reporting specific lists medications definitions.

Язык: Английский

Процитировано

36

Proactive Polypharmacy Management Using Large Language Models: Opportunities to Enhance Geriatric Care DOI
Arya Rao, John Kim, Winston Lie

и другие.

Journal of Medical Systems, Год журнала: 2024, Номер 48(1)

Опубликована: Апрель 18, 2024

Язык: Английский

Процитировано

17