The Effect of MoS2 and Si3N4 in Surface Plasmon Resonance Biosensors for HIV DNA Hybridization Detection: A Numerical Study DOI Creative Commons
Talía Tene, Diana Coello-Fiallos,

María de Lourdes Palacios Robalino

и другие.

Micromachines, Год журнала: 2025, Номер 16(3), С. 295 - 295

Опубликована: Фев. 28, 2025

This study presents a numerical investigation of surface plasmon resonance (SPR) biosensors incorporating silicon nitride (Si3N4) and molybdenum disulfide (MoS2) for HIV DNA hybridization detection. By optimizing the thickness Ag Si3N4 number MoS2 layers, two configurations, Sys2 (Ag-Si3N4) Sys3 (Ag-Si3N4-MoS2), were selected comparative analysis. Performance metrics, including angle shift, sensitivity, detection accuracy, quality factor, demonstrated that achieved highest sensitivity 210.9°/RIU an enhanced figure merit (86.98 RIU−1), surpassing state-of-the-art SPR sensors. Although exhibited lower 158.1°/RIU due to MoS2-induced optical losses, it provided limit detection, suggesting trade-off between spectral broadening. Compared previous biosensors, proposed configurations achieve superior while maintaining stability selectivity, positioning them as promising candidates next-generation nucleic acid platforms.

Язык: Английский

The Effect of MoS2 and Si3N4 in Surface Plasmon Resonance Biosensors for HIV DNA Hybridization Detection: A Numerical Study DOI Creative Commons
Talía Tene, Diana Coello-Fiallos,

María de Lourdes Palacios Robalino

и другие.

Micromachines, Год журнала: 2025, Номер 16(3), С. 295 - 295

Опубликована: Фев. 28, 2025

This study presents a numerical investigation of surface plasmon resonance (SPR) biosensors incorporating silicon nitride (Si3N4) and molybdenum disulfide (MoS2) for HIV DNA hybridization detection. By optimizing the thickness Ag Si3N4 number MoS2 layers, two configurations, Sys2 (Ag-Si3N4) Sys3 (Ag-Si3N4-MoS2), were selected comparative analysis. Performance metrics, including angle shift, sensitivity, detection accuracy, quality factor, demonstrated that achieved highest sensitivity 210.9°/RIU an enhanced figure merit (86.98 RIU−1), surpassing state-of-the-art SPR sensors. Although exhibited lower 158.1°/RIU due to MoS2-induced optical losses, it provided limit detection, suggesting trade-off between spectral broadening. Compared previous biosensors, proposed configurations achieve superior while maintaining stability selectivity, positioning them as promising candidates next-generation nucleic acid platforms.

Язык: Английский

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