Bioinspired micro‐ and nanostructured systems for cancer therapy DOI Creative Commons
Ruizhen Yang, Bing Zhang,

Xiawei Fei

и другие.

MedComm, Год журнала: 2024, Номер 5(12)

Опубликована: Ноя. 28, 2024

Abstract Numerous organisms in nature have demonstrated enhanced biocompatibility, precise tumor targeting capabilities, and efficient tissue traversal within the human body. Drawing inspiration from these organisms, researchers employed bioengineering, bioconjugation, micro‐ or nanotechnology to fabricate bioinspired nanostructured systems. These systems play a crucial role addressing limitations of conventional anticancer drugs nanomaterials concerning effective penetration physiological barriers, as well selective targeting, thereby leading improved therapeutic efficacy while minimizing nonspecific adverse effects on healthy cells. Consequently, extensive exploration has been undertaken across various cancer treatment modalities with some progressing into preclinical clinical stages. However, our understanding this field remains limited which may impede research progress, translation efforts, practical applications. Therefore, study presents systematic classification for therapy that comprehensively elucidates their sources design principles. Furthermore, it extensively discusses current status efforts identifying prevailing challenges exploring future prospects. This work will establish robust theoretical framework serve valuable reference facilitate advancements application field.

Язык: Английский

Metareview: a survey of active matter reviews DOI Creative Commons
Michael te Vrugt, Raphael Wittkowski

The European Physical Journal E, Год журнала: 2025, Номер 48(2)

Опубликована: Фев. 1, 2025

In the past years, amount of research on active matter has grown extremely rapidly, a fact that is reflected in particular by existence more than 1000 reviews this topic. Moreover, field become very diverse, ranging from theoretical studies statistical mechanics particles to applied work medical applications microrobots and biological systems artificial swimmers. This makes it difficult get an overview over as whole. Here, we provide such form metareview article surveys existing review articles books matter. Thereby, provides useful starting point for finding literature about specific

Язык: Английский

Процитировано

2

A narrative review of spermbots in assisted reproduction: Integrating AI for enhanced fertility outcomes and future innovations DOI Creative Commons

Neeraj Vishwakarma,

Nancy Nair,

Charu Pareek

и другие.

Asian Pacific Journal of Reproduction, Год журнала: 2025, Номер unknown

Опубликована: Апрель 11, 2025

Sperm-structure-integrating nanodecorated microrobots have shown promise in medicine delivery and infertility treatment. A variety of spermbots use cutting-edge nanomaterials 3D printing technology to enhance their functioning, such as biomimetic sperms flagellate microorganisms. The success rates assisted reproductive techniques like vitro fertilisation (IVF) intracytoplasmic sperm injection (ICSI) may increase a result these developments. Furthermore, the incorporation artificial intelligence (AI) into has potential optimize therapies by reducing inherited illnesses through genetic screening editing. However, before widespread implementation clinical practice, several critical aspects must be addressed. Thorough investigations biocompatibility, ethical considerations, long-term safety are necessary ensure that technologies safe effective for vivo applications.

Язык: Английский

Процитировано

0

Trends and projections of the burden of disease for male infertility in China from 1990 to 2021: an analysis from the Global Burden of Disease 2021 study DOI Creative Commons
Ran Xu,

Xinjun Wang,

Qiutong Lin

и другие.

Frontiers in Reproductive Health, Год журнала: 2024, Номер 6

Опубликована: Дек. 16, 2024

Currently, male infertility represents a serious disease burden worldwide, and China is one of the most affected countries. The aim this study was to examine evolution in during period 1990-2021 project trend for 2022-2036.

Язык: Английский

Процитировано

1

Bioinspired micro‐ and nanostructured systems for cancer therapy DOI Creative Commons
Ruizhen Yang, Bing Zhang,

Xiawei Fei

и другие.

MedComm, Год журнала: 2024, Номер 5(12)

Опубликована: Ноя. 28, 2024

Abstract Numerous organisms in nature have demonstrated enhanced biocompatibility, precise tumor targeting capabilities, and efficient tissue traversal within the human body. Drawing inspiration from these organisms, researchers employed bioengineering, bioconjugation, micro‐ or nanotechnology to fabricate bioinspired nanostructured systems. These systems play a crucial role addressing limitations of conventional anticancer drugs nanomaterials concerning effective penetration physiological barriers, as well selective targeting, thereby leading improved therapeutic efficacy while minimizing nonspecific adverse effects on healthy cells. Consequently, extensive exploration has been undertaken across various cancer treatment modalities with some progressing into preclinical clinical stages. However, our understanding this field remains limited which may impede research progress, translation efforts, practical applications. Therefore, study presents systematic classification for therapy that comprehensively elucidates their sources design principles. Furthermore, it extensively discusses current status efforts identifying prevailing challenges exploring future prospects. This work will establish robust theoretical framework serve valuable reference facilitate advancements application field.

Язык: Английский

Процитировано

0