Applied Sciences,
Год журнала:
2023,
Номер
13(2), С. 1152 - 1152
Опубликована: Янв. 14, 2023
Meibomitis
is
an
ocular
disease
which
leads
to
a
dysfunction
of
the
meibomian
glands.
This
ophthalmologic
may
cause
severe
pain
and
obvious
vision
loss.
The
therapeutic
protocol
used
in
treatment
this
pathology
consists
local
systemic
antibiotic
therapy.
results
obtained
using
approach
are
scarce
and,
many
cases,
result
adverse
events.
In
study,
we
propose
alternative
original
TECAR
therapy
treatments
meibomitis
disease.
endogenous
heat
produced
by
device
beneficial
effects
from
both
histological
anatomical
point
view.
Different
parameters
(TBUT,
interferometry,
tear
meniscus
height,
meibography
OCTA)
were
evaluated
before
treatments,
immediately
afterwards,
15
days
after
end
treatments.
suggest
new
possible
use
on
ophthalmological
patients,
opening
innovative
scenario
non-invasive
manner.
Delhi Journal of Ophthalmology,
Год журнала:
2025,
Номер
35(1), С. 10 - 16
Опубликована: Янв. 1, 2025
Meibomian
gland
dysfunction
(MGD)
is
a
leading
cause
of
dry
eye
disease,
characterized
by
abnormal
meibum
production
and
glandular
obstruction,
resulting
in
compromised
tear
film
stability
ocular
discomfort.
This
review
article
aims
to
provide
comprehensive
overview
the
latest
developments
diagnosis
treatment
MGD.
Diagnostic
innovations,
including
non-invasive
imaging
techniques,
analysis,
interferometry,
have
enhanced
our
ability
detect
early-stage
MGD
assess
disease
severity
more
accurately.
Newer
therapeutic
modalities
like
intense
pulsed
light
therapy,
pharmacological
agents
targeting
inflammation
function,
along
with
standard
measures
hot
fomentation,
eyelid
massage
shown
promising
results
improving
symptoms
restoring
meibomian
health.
By
summarizing
current
landscape
diagnostics
therapeutics,
this
highlights
ongoing
efforts
refine
clinical
care
enhance
patient
outcomes
prevalent
condition.
Purpose:
To
evaluate
the
efficacy
and
safety
of
intense
pulsed
light
(IPL)
combined
with
meibomian
gland
expression
(MGX)
for
treatment
dry
eye
disease
dysfunction
associated
chronic
Stevens–Johnson
syndrome
toxic
epidermal
necrolysis.
Methods:
This
prospective
noncomparative
interventional
study
included
29
patients
(58
eyes)
who
underwent
3
sessions
IPL
MGX
at
2-week
intervals.
Subjective
symptoms
(ocular
surface
index
score)
objective
tests:
matrix
metalloproteinase
9,
tear
meniscus
height,
bulbar
redness
score,
film
lipid
layer
thickness
(LLT),
Schirmer
I
test,
conjunctival
corneal
staining,
loss,
score
[meibomian
(MGS)],
break-up
time
were
assessed
baseline
after
4,
8,
12
weeks.
Results:
Twenty-nine
individuals
(57
in
this
analysis.
The
ocular
decreased
significantly
from
60.07
±
23.34
(baseline)
to
38.36
22.39
(after
90
days)
(
P
<
0.01).
fluorescein
lissamine
green
staining
scores,
MGS,
LLT
improved
In
contrast,
there
no
significant
changes
height
values,
9
positivity,
meibography
superior
inferior
eyelids,
time.
Ocular
or
skin
complications
not
observed.
Conclusions:
Three
therapy
followed
by
seemed
be
safe
effective
treating
dysfunction,
improving
vision-related
quality
life,
symptoms,
signs,
such
as
days
Heliyon,
Год журнала:
2024,
Номер
10(13), С. e33852 - e33852
Опубликована: Июнь 28, 2024
The
treatment
and
management
of
ocular
surface
diseases
have
shifted
towards
a
co-treatment
approach
focusing
on
overall
homeostasis.
When
treating
issues
related
to
the
eye,
it
is
essential
not
only
focus
damaged
or
disabled
areas
but
also
consider
larger
picture.
Meibomian
gland
dysfunction
(MGD),
Demodex
infection,
blepharitis
all
interact
at
eyelid
site
can
cause
damage
varying
degrees.
Palpebral
lesions
disrupt
balance
homeostasis,
leading
dry
eye
keratitis.
Traditional
treatments,
such
as
manual
physical
hot
compress
massage,
limited
effectiveness
due
structure
eyelid.
However,
intense
pulsed
light
(IPL)
technology
uses
penetrating
energy
generate
heat
energy,
which
eliminate
inflammation
capillaries
kill
Demodex.
Additionally,
LipiFlow
thermal
effect
compression
provide
more
vital
longer-lasting
therapeutic
MGD
by
excluding
other
primary
causes
inflammation.
Therefore,
personalized
techniques
based
photothermal
effects
may
be
effective.
In
future,
IPL
potentially
dismiss
immune-inflammation
factors
causing
disease
block
delivery
systemic
immune-related
diseases.
European Journal of Ophthalmology,
Год журнала:
2023,
Номер
34(3), С. 700 - 707
Опубликована: Сен. 6, 2023
Purpose
To
demonstrate
that
intense
pulsed
light
therapy
(IPL)
of
the
upper
and
lower
eyelids
with
meibomian
gland
expression
(MGX)
is
effective
in
improving
dry
eye
disease
due
to
dysfunction
(MGD).
Methods
Patients
ocular
discomfort
(Ocular
Surface
Disease
Index
-OSDI-
above
13)
signs
MGD
were
recruited.
All
patients
underwent
OSDI,
visual
acuity
(VA),
intraocular
pressure,
Schirmer
test,
meibography,
non-invasive
tear
breakup
time
(NITBUT),
slit-lamp
examination
(corneal
conjunctival
staining,
hyperemia,
expressibility,
meibum
quality),
osmolarity
lipid
layer
thickness.
IPL
was
performed
Optima
(Lumenis
Ltd.)
following
a
standardized
protocol
on
both
eyes,
inferior
eyelid
MGX.
received
four
sessions
separated
by
two
weeks
each.
Four
after,
examinations
repeated.
Results
160
(320
eyes)
included,
which
108
(67.5%)
women
mean
age
59.2
±
15.08
(range
20–89).
After
sessions,
VA,
osmolarity,
thickness,
NITBUT,
corneal
quality,
Meiboscore
test
improved
(all,
p
<
0.027).
Changes
initial
average
NITBUT
increased
severity
(according
OSDI).
Increased
pre-treatment
staining
associated
an
improvement
OSDI
0.040).
No
adverse
events
noted.
Conclusions
The
combination
MGX
safe
for
treatment
MGD.
severe
present
greater
improvements.
Purpose:
To
compare
different
light-based
devices,
namely,
intense
pulsed
light
(IPL)
and
IPL
with
low-level
therapy
(LLLT),
in
the
treatment
of
meibomian
gland
dysfunction
(MGD).
Methods:
This
was
a
prospective,
observational
study
that
included
patients
MGD.
Group
1
58
eyes
treated
(eye-light®,
Espansione
Marketing
S.p.A.,
Bologna,
Italy),
followed
by
LLLT
(my-mask®,
Italy);
2
60
(E>Eye®,
E-Swin,
Houdan,
France);
3
(Thermaeye
Plus®,
OptiMed,
Sydney,
Australia).
The
presence
symptoms
(Ocular
Surface
Disease
Index
(OSDI))
ocular
surface
changes
were
evaluated
at
baseline,
three
weeks,
six
months
after
treatment.
Results:
At
week
three,
there
an
improvement
OSDI
all
groups
(p<0.001),
without
differences
among
them
(p=0.339).
lipid
layer
thickness
(LLT)
increased
Groups
similar
variation
(p=0.144).
Patients
superior
lower
LLT
baseline
had
greatest
respective
parameters
(p<0.001).
basal
tear
flow
(p=0.012).
Corneal
staining
(CS)
significantly
decreased
(p<0.001)
months,
compared
to
further
(p=0.007),
1,
increase
CS
(p=0.011).
Conclusion:
led
sustained
decrease
patients’
symptoms,
even
months.
Different
devices
seem
have
beneficial
effects.
Adding
appears
additional
long-term
effect
as
well
positive
effects
on
lacrimal
gland.
Cornea,
Год журнала:
2024,
Номер
44(2), С. 157 - 162
Опубликована: Июль 5, 2024
Purpose:
The
purpose
of
this
study
was
to
report
the
outcomes
quantum
molecular
resonance
(QMR)
electrotherapy
in
management
refractory
pediatric
ocular
rosacea.
Methods:
This
is
a
retrospective
case
series
on
3
female
patients
(ages
12,
15,
14
years)
with
Two
presented
corneal
stromal
neovascularization
and
punctate
epithelial
erosions
while
1
patient
scarring
paracentral
thinning.
After
failing
conservative
management,
were
treated
4
consecutive
QMR
sessions
intensity
set
at
5
corresponding
average
power
12
W,
60
V
voltage
200
mA
current.
Informed
consent
obtained
for
off-label
use.
Patients
assessed
changes
vision,
foreign
body
sensation,
tearing,
photophobia,
redness
each
visit
determine
symptomatic
improvement.
Outcome
measures
include
best-corrected
visual
acuity,
use
supplemental
therapies
(eg
topical
steroids)
symptom
relief,
extent
via
serial
slitlamp
photography,
scar
remodeling
high
resolution
anterior
segment
optical
coherence
tomography.
Results:
experienced
improvement
acuity
after
electrotherapy.
Corneal
regressed
significantly
all
patients.
months
post-QMR
electrotherapy,
evident
tomography
2
All
able
discontinue
immunosuppressants
remain
symptom-free
1.5
years
follow-up.
Conclusions:
promising
alternative
treatment
rosacea
childhood
puberty,
it
may
potentiate
remodeling.
Ophthalmology and Therapy,
Год журнала:
2024,
Номер
13(10), С. 2715 - 2730
Опубликована: Авг. 16, 2024
To
evaluate
the
long-term
effects
of
intense
pulsed
light
(IPL)
therapy
on
patients
with
dry
eye
disease
(DED)
associated
meibomian
gland
dysfunction
(MGD).
Current Opinion in Allergy and Clinical Immunology,
Год журнала:
2024,
Номер
24(5), С. 397 - 403
Опубликована: Авг. 13, 2024
Integrative
medicine
techniques
are
increasingly
accepted
into
the
treatment
paradigm
for
many
chronic
disorders
including
eye
disease.
Over
71%
of
patients,
67%
those
with
disorders,
use
some
form
therapy.
Physicians
should
be
well
versed
in
evidence-based
therapies
to
know
how
refer
patients
best
complimentary
care.
We
highlight
most
effective
integrative
therapeutics
from
different
complementary
paradigms
offer
a
framework
approaching
therapy
ocular
surface
(OSDs).
