Cause-effect factors of rhinosinusitis poliposa development

Russian Rhinology, Год журнала: 2023, Номер 31(2), С. 124 - 124

Опубликована: Янв. 1, 2023

Язык: Английский

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Assessment of quality of life in children with allergic rhinitis

Allergology and Immunology in Pediatrics, Год журнала: 2025, Номер 4, С. 40 - 49

Опубликована: Янв. 22, 2025

Introduction. Atopic rhinitis (AR) affects 10–24 % of the population in Russia, often manifesting itself early childhood. AR is as one most prevalent allergic diseases, significantly impacting children’s quality life, affecting their physical health, psychoemotional well-being, well social and educational aspects life. Materials Methods. The study analyzed responses from 43 children aged 6 to 17, presenting with exacerbations rhinitis. SNOT-22 test was used assess Results. identified a substantial deterioration life among patients suffering analysis revealed that nasal discharge (rhinorrhea) affected 27 (63 %) participants, congestion impacted 19 (44 individuals, sneezing 16 (37 patients, coughing 15 (35 postnasal drip observed 9 (21 participants. These symptoms well-being children, activity academic performance. Conclusions. Hypoxia, induced by impaired ventilation respiratory tract, can negatively affect brain function, leading decreased attention span, memory impairment, cognitive dysfunction. results highlight importance comprehensive approach treating which should encompass not only pharmacological interventions alleviate but also programs both for parents children. proves valuable everyday clinical practice pediatricians allergists, serving an effective tool dynamic monitoring short-term long-term effects this condition’s therapy.

Язык: Английский

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Effect of post-COVID syndrome on the quality of life of patients with allergic rhinitis and eosinophilic phenotype of chronic polyposis rhinosinusitis

Russian Medicine, Год журнала: 2023, Номер 29(4), С. 277 - 290

Опубликована: Авг. 18, 2023

BACKGROUND.An urgent issue of modern medicine is the study quality life people with post-COVID syndrome.Particular emphasis placed on patients various forms allergic rhinitis associated comorbid conditions such as polyposis rhinosinusitis.These diseases are still common and tend to increase.In this context, effect conservative methods treatment rhinosinus will improve effectiveness therapy. AIMS: To assess impact syndrome eosinophilic phenotype chronic rhinosinusitis determine MATERIALS AND METHODS: In period from May December 2021, a was conducted in 62 against background post-covid syndrome, which 32 suffered polypous 30 rhinitis.The disease coronavirus infection registered 2-3 months before visit otorhinolaryngologist.The comparison groups included 65 people, including 33 Russian version standard SF-36 questionnaire used collect anamnesis.A visual analogue scale measure intensity rhinological symptoms.All were examined three times: treatment, 1 3 after course RESULTS: A comparative analysis indicators showed direct dependence condition infection. CONCLUSIONS: The use assessment at stages makes it possible therapy timely adjust treatment.

Язык: Английский

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Some immunological aspects of targeted therapy in polypous rhinosinusitis

Russian Journal of Immunology, Год журнала: 2023, Номер 26(3), С. 301 - 306

Опубликована: Авг. 11, 2023

Over the past decade, targeted therapy with various monoclonal antibodies has become particularly relevant for treatment of chronic polypous rhinosinusitis (PR). This is primarily due to high incidence rate, polyetiological origin and pathogenetic features polyposis development, low effectiveness existing approaches, tendency relapse, comorbid conditions. The article provides a brief historical background concerning predictors mucous membrane remodeling in nasal cavity paranasal sinuses at stages formation thus justifying need implementation schedules. Considering leading role Th2-inflammation immunopathogenesis developing vegetations, influence upon theoretically evaluated, we highlight some important issues that should be further specified. Undoubtedly, inhibition synthesis necessary interleukins leads improvement clinical symptoms reduced size vegetations. At same time, real biochemical transformations mucosa have been scarcely studied. E.g., an attempt inhibit cytokine may lead indirect blockage other pro-inflammatory cytokines. In future, it study pharmacodynamics drugs order clarify distinct contraindications their use.

Язык: Английский

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Priority choice of topical antibacterial drugs in the commonly accepted paradigm of acute rhinosinusitis treatment

Meditsinskiy sovet = Medical Council, Год журнала: 2023, Номер 19, С. 96 - 104

Опубликована: Ноя. 18, 2023

Introduction. In the complex therapy of acute rhinosinusitis, topical drugs with different mechanisms action and influence on main links in pathogenesis infectious lesions mucous membrane paranasal sinuses are widely used. Local antibacterial, as well mucolytic vasoconstrictor effects do not inhibit mucociliary clearance, have a convenient release form ensure dosing accuracy each use. Aim. Evaluation clinical effectiveness use antibiotic aminoglycoside group combination drug having vasoconstrictive domestic production treatment bacterial rhinosinusitis. Mat erials methods. The study involved 30 patients verified diagnosis rhinosinusitis moderate severity aged 18 to 68 years, who were divided into two groups. Patients first (n = 15), addition (antibacterial, antihistamine unloading therapy, anti-inflammatory puncture treatment), used bactericidal effect from aminoglycosides (Tramicent). second 15) supplemented same (Rhinostein®). was evaluated based results three visits doctor within weeks. Results. positive dynamics subjective objective status both groups noted. By 3rd visit (10–14 days), manifestations Tramicent Rhinostein® additional 2 times lower than at compared only therapy. absence complaints after 2nd noted by 15% examined, 1st – 10%. Conclusions. Topical containing active substance framycetin sulfate (Tramicent) spray is safe effective remedy its (Rhinostein®) significantly reduces duration improves quality life patients.

Язык: Английский

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Motivation of the patient to perform aesthetic rhinosurgical intervention, topical issues in identifying the true reasons: A review

Consilium Medicum, Год журнала: 2024, Номер 25(12), С. 822 - 826

Опубликована: Март 12, 2024

From time immemorial, people have sought to improve their body and appearance by resorting various medical, non-drug surgical interventions. The most advanced direction in this context has been remains facial cosmetic surgery, which, being a kind of standard that allows you achieve perfection, encourages change an operative way, which is not always justified. common after desire when visiting plastic surgeon the shape nose. main motive for rhinoplasty low self-esteem, dissatisfaction with size nose, opinion, prevents them from achieving success personal lives, building career, etc. As rule, these are ethnic groups who seek “Europeanize” nose face according modern aesthetic canons, dysmorphophobia, young girls boys. Often there cases patients, having received desired result, make claims surgeons embark on litigation. Therefore, planning rhinoplasty, it necessary find out several important questions: psychological reasons motivated rhinoplasty; whether patient mental deviations what external influences internal deviations. Patients presenting following features at high risk should give reason reconsider rhinoplasty.

Язык: Английский

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External otitis media: modern possibilities for improving the effectiveness of treatment and the quality of life of patients

Meditsinskiy sovet = Medical Council, Год журнала: 2024, Номер 7, С. 17 - 24

Опубликована: Май 17, 2024

Introduction. Polyethologicity of otitis externa with inflammation the auricle, ear canal and outer layer eardrum, persistent course high probability recurrence necessitates improved treatment. Aim. To evaluate effectiveness use impact on quality life combined drops antimicrobial local anesthetic effects. M ate r ials methods. A simple randomized controlled clinical trial involved 56 people, including 25 women 31 men aged 32 to years, suffering from acute diffuse externa. Clinical efficacy, recovery time were evaluated in two groups: groups 1 (n = 27), patients receiving containing choline acetate as therapy, group 2 29) taking a multicomponent drug polymyxin B sulfate 1,000,000 IU, neomycin 0.5 g (375,000 IU) lidocaine hydrochloride form drops. The assessment otalgia, hearing loss discharge external auditory was carried out VAS, scale using SF-36 general questionnaires. Results discussion. There positive dynamic manifestations restoration quality-of-life indicators shorter period (3rd, 5th day) disappearance all main symptoms (7th good tolerability absence side effects second drug. Conclusions. combination topical drugs an complex therapy significantly patients.

Язык: Английский

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Acute respiratory infections of the upper respiratory tract, aspects of mucoactive therapy

Meditsinskiy sovet = Medical Council, Год журнала: 2024, Номер 7, С. 34 - 43

Опубликована: Май 18, 2024

Introduction. Acute laryngotracheitis occurs at any age and is a complication of acute respiratory infection with frequency up to 40%. One the main clinical symptoms an unproductive paroxysmal cough. According literature, phytotherapy safe effective part conservative therapy included in recommendations. Aim. To evaluate effectiveness use mucolytic phytopreparations treatment complicated by laryngotracheitis. Mat erials methods. A randomized simple controlled trial was conducted which 74 patients aged 18 45 years laryngitis participated. All were randomly divided into 3 groups: group 1 (n = 24) received standard without expectorants; 2 25) – acetylcysteine; using herbal preparation based on ivy leaf extract form syrup. Assessment severity quality life carried out 5 th , 7 10 day therapy. Conclusions. The extract, has expectorant effect complex against background viral infection, allowed us obtain stable positive dynamics shorter time (5 treatment) disappearance all day.

Язык: Английский

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Non-drug methods of influencing the pharyngeal tonsil in the complex therapy of chronic adenoiditis

Consilium Medicum, Год журнала: 2024, Номер 26(03), С. 153 - 158

Опубликована: Май 18, 2024

Aim. To compare the dynamics of clinical course chronic adenoiditis in children and evaluate changes levels products oxidative modification proteins pharyngeal tonsil tissues under influence physical methods. Materials The study involved 84 patients with a picture inflammation brain hypertrophy adenoid vegetations 3rd degree, who were referred for surgical treatment as planned. All belonged to age group from 3 15 years. envelope method was used, randomized into groups. Group 1 (n=32) included did not receive exposure methods preoperative period; Participants 2nd (n=27) received low-frequency ultrasonic (LFU) therapy combination red spectrum photochromotherapy (FCT) period, participants (n=25) NUS cavitation monotherapy before surgery. Statistical data obtained using SPSS Statistics 19.0 software package. nonparametric Kruskal–Wallis test used identify differences between independent groups; pairwise comparison groups, Mann–Whitney used. Results. Analysis results showed that severity studied signs groups comparable each other on 1st day, i.e. starting treatment. endoscopic examination are graded 0 points. nasal obstruction difficulty breathing (control) day 7.7 points, 2 – 7.4 7.5 Patients underwent anterior posterior rhinoscopy. best result LFU FCT. There significant decrease size absence discharge surface vegetations, which reflects high effectiveness this Conclusion. use FCT leads improved amount cavity.

Язык: Английский

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Chronic adenoiditis and its effect on the reactivity of the bronchopulmonary system, the possibility of non-drug correction

Meditsinskiy sovet = Medical Council, Год журнала: 2024, Номер 9, С. 108 - 115

Опубликована: Июнь 6, 2024

Introduction . In pediatric otorhinolaryngological practice, chronic adenoiditis is one of the most common diseases and causes search for additional effective methods treatment. Aim To evaluate clinical effectiveness use aqueous solutions treated with low-frequency ultrasound high specific energy monochromatic light radiation in complex therapy children. Materials The number participants study was 104 patients aged 4 to 15 years a verified diagnosis were divided into 3 groups depending on A comparative analysis results obtained carried out before start (day 0) 7th day after state nasopharynx assessed using flexible nasopharyngoscope, as well structure middle ear auditory tube during acoustic impedancemetry. Results course treatment ultrasonic cavitation combination photochromotherapy made it possible relieve signs 62% cases (p < 0.001), reduce grade III adenoid hypertrophy by 54% = 0.035), 2 times 0.05) relapses adenoiditis. group children cavitation, positive effect 3.3 [CI 0.75; 14.6] higher compared control group, 3.6 0.85; 15.5]. absence adenotomy effect. Conclusion data showed that inclusion non-drug physical influence (low-frequency both monotherapy photochromotherapy) can surgical interventions organs lymphopharyngeal ring – pharyngeal tonsil.

Язык: Английский

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