REHABS: An Innovative and User-Friendly Device for Rehabilitation DOI Creative Commons
Patrizia Vizza, Nicola Marotta, Antonio Ammendolia

и другие.

Bioengineering, Год журнала: 2023, Номер 11(1), С. 5 - 5

Опубликована: Дек. 21, 2023

Rehabilitation is a complex set of interventions involving the assessment, management, and treatment injuries. It aims to support facilitate an individual’s recovery process by restoring physiological function, e.g., limb movement, compromised physical impairments, injuries or diseases condition as close normal possible. Innovative devices solutions make rehabilitation patients easier during their daily activities. Devices physicians physiotherapists in monitoring measuring patients’ improvements rehabilitation. In this context, we report design implementation low-cost system, which programmable device designed tele-rehabilitation upper limbs. The proposed system includes mechanism acquire analyze data signals related processes.

Язык: Английский

N-of-1 medicine DOI Creative Commons
Peter Wang, Qiao Ying Leong, Ni Yin Lau

и другие.

Singapore Medical Journal, Год журнала: 2024, Номер 65(3), С. 167 - 175

Опубликована: Март 1, 2024

Abstract The fields of precision and personalised medicine have led to promising advances in tailoring treatment individual patients. Examples include genome/molecular alteration-guided drug selection, single-patient gene therapy design synergy-based combination development, these approaches can yield substantially diverse recommendations. Therefore, it is important define each domain delineate their commonalities differences an effort develop novel clinical trial designs, streamline workflow rethink regulatory considerations, create value healthcare economics assessments, other factors. These segments are essential recognise the diversity within domains accelerate respective workflows towards practice-changing healthcare. To emphasise points, this article elaborates on concept digital health medicine-enabled N-of-1 medicine, which individualises regimen dosing using a patient’s own data. We will conclude with recommendations for consideration when developing based emerging digital-based platforms.

Язык: Английский

Процитировано

5
Prescription Digital Therapeutics: An Emerging Treatment Option for Negative Symptoms in Schizophrenia DOI
Daniel Fulford, Lisa A. Marsch,

Abhishek Pratap

и другие.

Biological Psychiatry, Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

5
Personalized dose selection for the first Waldenström macroglobulinemia patient on the PRECISE CURATE.AI trial DOI Creative Commons
Agata Blasiak, Lester W. J. Tan, Li Ming Chong

и другие.

npj Digital Medicine, Год журнала: 2024, Номер 7(1)

Опубликована: Авг. 27, 2024

Abstract The digital revolution in healthcare, amplified by the COVID-19 pandemic and artificial intelligence (AI) advances, has led to a surge development of technologies. However, integrating health solutions, especially AI-based ones, rare diseases like Waldenström macroglobulinemia (WM) remains challenging due limited data, among other factors. CURATE.AI, clinical decision support system, offers an alternative big data approaches calibrating individual treatment profiles based on that individual’s alone. We present case study from PRECISE CURATE.AI trial with WM patient, where, over two years, provided dynamic Ibrutinib dose recommendations clinicians (users) aimed at achieving optimal IgM levels. An 80-year-old male newly diagnosed requiring anemia was recruited for CURATE.AI-based dosing Bruton tyrosine kinase inhibitor Ibrutinib. primary secondary outcome measures were focused scientific logistical feasibility. Preliminary results underscore platform’s potential enhancing user patient engagement, addition efficacy. Based two-year-long enrollment into CURATE.AI-augmented treatment, this showcases how AI-enabled tools can management diseases, emphasizing integration AI enhance personalized therapy.

Язык: Английский

Процитировано

4
Assessment of priorities, quality, and inclusivity of digital therapeutics trials in China DOI Creative Commons
Ziming Wang, Xinxin Xia, Weijia Lü

и другие.

npj Digital Medicine, Год журнала: 2025, Номер 8(1)

Опубликована: Фев. 4, 2025

Abstract Digital therapeutics (DTx) are software-driven solutions for prevention, treatment, and management of medical conditions. Despite a pro-DTx momentum in China, global DTx trial assessments overlooked the country. We identified 756 trials China analyzed their characteristics quality parameters. Over 70% were funded by governments, hospitals, universities, with tertiary hospitals eastern leading most trials. 44.8% used automated DTx, 39.2% DTx-guided. Most focused on (52.5%) treatment (38.1%), few prevention (9.4%). Mental, behavioral, or neurodevelopmental disorders represented condition category focus. Recent declines median sample size, duration, mean number sites noted. Only 18% at low overall risk bias. While recognizing rapid development we call better design methodological rigor, prioritization preventive primary care, wider scope, higher inclusivity.

Язык: Английский

Процитировано

0
A group concept mapping study of stakeholder perspectives on digital therapeutics economic value drivers DOI Creative Commons
Yoann Sapanel, L. Martin Cloutier, Gabriel Tremblay

и другие.

npj Digital Medicine, Год журнала: 2025, Номер 8(1)

Опубликована: Апрель 10, 2025

Язык: Английский

Процитировано

0
Adoption of Digital Therapeutics in Europe DOI Creative Commons

Amelie Fassbender,

Shaantanu Donde,

Mitchell Silva

и другие.

Therapeutics and Clinical Risk Management, Год журнала: 2024, Номер Volume 20, С. 939 - 954

Опубликована: Дек. 1, 2024

Digital therapeutics (DTx) are an emerging medical therapy comprising evidence-based interventions that regulatory approved for patient use, or under development, a variety of conditions, including hypertension, cancer, substance use disorders and mental disorders. DTx have significant potential to reduce the overall burden on healthcare systems offer economic benefits. There is currently no specific legal regulation in EU. Although European countries similar approaches digital health solutions, adoption varies across continent. The aim this narrative review discuss levels Europe, explore possible strategies improve adoption, with goal higher rates more consistent article discusses reimbursement landscape Europe; validation requirements DTx, importance co-design ecosystem-centric approach development DTx. Also considered drivers prescription practices as well perspectives these therapeutics. explores factors may contribute low lack harmonisation reimbursement; sociodemographic factors; status; ethical concerns; challenges surrounding AI; knowledge awareness among professionals (HCPs) patients, data standards interoperability. Efforts access Europe described. Finally, framework improved uptake proposed.

Язык: Английский

Процитировано

3
Smartphone Apps for Parents of Preterm Infants from NICU to Home: A Quality, Evidence-Based Content and Data Protection Assessment DOI
R. Coquoz,

Camille Pellaton,

Leo Bettelini

и другие.

Lecture notes in business information processing, Год журнала: 2024, Номер unknown, С. 209 - 224

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

2
Using Digital Health Technology to Prevent and Treat Diabetes DOI
Mark A. Clements, Neal Kaufman,

Eran Mel

и другие.

Diabetes Technology & Therapeutics, Год журнала: 2024, Номер 26(S1), С. S - 107

Опубликована: Март 1, 2024

Язык: Английский

Процитировано

0
REHABS: An Innovative and User-Friendly Device for Rehabilitation DOI Creative Commons
Patrizia Vizza, Nicola Marotta, Antonio Ammendolia

и другие.

Bioengineering, Год журнала: 2023, Номер 11(1), С. 5 - 5

Опубликована: Дек. 21, 2023

Rehabilitation is a complex set of interventions involving the assessment, management, and treatment injuries. It aims to support facilitate an individual’s recovery process by restoring physiological function, e.g., limb movement, compromised physical impairments, injuries or diseases condition as close normal possible. Innovative devices solutions make rehabilitation patients easier during their daily activities. Devices physicians physiotherapists in monitoring measuring patients’ improvements rehabilitation. In this context, we report design implementation low-cost system, which programmable device designed tele-rehabilitation upper limbs. The proposed system includes mechanism acquire analyze data signals related processes.

Язык: Английский

Процитировано

0