Higher body roundness index (BRI) increases infertility among U.S. women aged 18–45 years DOI Creative Commons

Hongyang Gong,

Shuqin Duan,

Seok Choi

и другие.

BMC Endocrine Disorders, Год журнала: 2024, Номер 24(1)

Опубликована: Дек. 18, 2024

Abstract Objective Infertility is associated with obesity. The Body Roundness Index (BRI) a body measurement index related to obesity that more accurately assesses and visceral fat levels. However, the relationship between BRI infertility remains unclear. Therefore, this study aims determine infertility. Methods This utilized data from National Health Nutrition Examination Survey (NHANES) 2013 2018 included 3,528 women aged 18–45 years. Multivariate logistic regression was employed investigate association Restricted cubic spline (RCS) analysis explored linear or non-linear Interaction analyses were conducted on subgroups validate findings. To verify robustness of results, we performed several sensitivity analyses, including propensity score matching(PSM) multiple imputations for missing data. Furthermore, predictive capabilities various anthropometric indices—including BRI, weight-adjusted waist (WWI), mass (BMI), weight—on incidence assessed using Receiver Operating Characteristic (ROC) curve analysis. Results There significant positive After adjusting covariates, each unit increase in there 12% probability ( P < 0.001). correlation persisted when categorized into quartiles. Moreover, as increased, trend towards higher prevalence dose-response indicated infertility, risk. subgroup imputations. ROC revealed had superior capability compared traditional indices, an area under (AUC) 0.618 (95% CI, 0.588–0.648). Conclusion results show strong Clinical trial number Not Applicable.

Язык: Английский

Association between obstructive sleep apnea and visceral adiposity index and lipid accumulation product: NHANES 2015–2018 DOI Creative Commons

Tingfeng Zhou,

Shihao Chen,

Jiesheng Mao

и другие.

Lipids in Health and Disease, Год журнала: 2024, Номер 23(1)

Опубликована: Апрель 10, 2024

Obesity refers to a significant contributor the development of obstructive sleep apnea (OSA). Early prediction OSA usually leads better treatment outcomes, and this study aims employ novel metabolic markers, visceral adiposity index (VAI), lipid accumulation product (LAP) evaluate relationship OSA.

Язык: Английский

Процитировано

28
Obesity, body fat distribution and eye diseases DOI Creative Commons
Francesca Bosello,

Angiola Vanzo,

Chiara Zaffalon

и другие.

Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity, Год журнала: 2024, Номер 29(1)

Опубликована: Май 6, 2024

Abstract Background The prevalence of obesity, a chronic disease, is increasing, and obesity now considered global epidemic. Eye diseases are also increasing worldwide have serious repercussions on quality life as well increasingly high costs for the community. relationships between ocular pathologies not yet clarified pathologically homogeneous: they seem to be somehow linked excess body fat, especially distribution adipose tissue its ectopic deposits. Purpose Our objective was examine associations anthropometric indices, including mass index (BMI), waist circumference (WC), waist/hip ratio (WHR), risk most widespread eye diseases, with particular attention given significant metabolic mechanisms. Methods This article provides narrative overview effect measurements fat prevalent diseases. We used MEDLINE/PubMed, CINAHL, EMBASE, Cochrane Library databases from 1984 2024. In addition, we hand-searched references retrieved articles explored number related websites. A total 153 publications were considered. Results There evidence that associated several Waist (WC) (WHR) been observed stronger positive than BMI. Conclusions Obesity must factor diseases; hence, multidisciplinary multidimensional approach treating which affects health, important. prevention treatment lifestyle factors, diet physical activity, weight changes, both loss gain, should overlooked. Level V review.

Язык: Английский

Процитировано

7
Association between Chinese visceral adiposity index and lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH): a national cohort study DOI Creative Commons

K M Chang,

Bo Li, Gang Wang

и другие.

BMC Urology, Год журнала: 2025, Номер 25(1)

Опубликована: Янв. 23, 2025

Benign prostatic hyperplasia (BPH) and its related lower urinary tract symptoms (LUTS) are commonly observed among aging males have a substantial effect on quality of life. Metabolic syndrome, with specific focus obesity, is believed to play role in the development BPH. This study intends explore relationship between several obesity-related metrics, including Chinese Visceral Adiposity Index (CVAI), LUTS/BPH within national cohort men. Data from China Health Retirement Longitudinal Study (CHARLS) 2015 were analyzed, encompassing sample 5,735 male participants aged 45 older. Eight indices—namely Body mass index (BMI), Waist-height ratio (WHtR), Triglyceride-glucose.BMI (TyG.BMI), TyG. Waist circumference (TyG.WC), TyG.WHtR, CVAI, adiposity (VAI), A body shape (ABSI)—were examined. Logistic regression models, adjusted for potential confounders, utilized evaluate associations these indices LUTS or The predictive capabilities further assessed using receiver operating curves (ROC). Among participants, 718 (12.5%) diagnosed LUTS/BPH. All significantly higher group compared healthy group. CVAI demonstrated highest ability LUTS/BPH, an area under curve (AUC) 0.58. highlighted nonlinear indices, CVAI. underscores significant association visceral fat, as measured by risk emerged most effective predictor evaluated, suggesting utility identifying individuals at Further prospective studies needed confirm findings elucidate underlying mechanisms.

Язык: Английский

Процитировано

1
Association of diabetic retinopathy with plasma atherosclerotic index, visceral obesity index, and lipid accumulation products: NHANES 2005–2008 DOI Creative Commons

Bin Wei,

Lin Zhou, Ben-Liang Shu

и другие.

Lipids in Health and Disease, Год журнала: 2024, Номер 23(1)

Опубликована: Окт. 10, 2024

Abdominal obesity, a significant risk factor for the progression of diabetic retinopathy (DR), may lead to improved visual outcomes through early assessment. This study aims evaluate any potential associations between DR and novel lipid metabolism markers, including Atherogenic Index Plasma (AIP), Visceral Adiposity (VAI), Lipid Accumulation Product (LAP).

Язык: Английский

Процитировано

4
A National trends in type 2 diabetes in South Korea, including the COVID-19 pandemic, 1998-2021: A nationally representative survey study DOI
Yejun Son, Jaeyu Park, Hye Jun Kim

и другие.

Life Cycle, Год журнала: 2024, Номер 4

Опубликована: Сен. 3, 2024

Язык: Английский

Процитировано

3
Coffee intake, plasma caffeine levels, and diabetic microvascular complications: a Mendelian randomization study DOI

Yue Zhou,

Song Li, Xi Yin

и другие.

Nutrition Metabolism and Cardiovascular Diseases, Год журнала: 2025, Номер unknown, С. 103856 - 103856

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
The relationship between VAI, LAP, and depression and the mediation role of sleep duration–evidence from NHANES 2005–2020 DOI Creative Commons
Yiqing Huang, Dan Zhao, Zhongfang Yang

и другие.

BMC Psychiatry, Год журнала: 2025, Номер 25(1)

Опубликована: Март 11, 2025

The relationship between obesity and mental health has attracted attention. However, large sample studies on the visceral fat depression are lacking. This study aimed to explore by using adiposity index (VAI) lipid accumulation product (LAP). Additionally, it sought potential mediating role of sleep duration in these associations. data used current cross-sectional investigation from National Health Nutrition Examination Survey (NHANES) spanning 2005 2020, including 19,659 participants. Depression was measured nine-item Patient Questionnaire. Weighted multivariable regression analysis evaluate correlation VAI LAP with depression. non-linear determined smooth curve fitting threshold effect analysis. mediation performed investigate duration. stability assessed through sensitivity were closely related In fully adjusted model, highest quartile increased association 52% (OR = 1.52, 95% CI 1.20–1.92, P < 0.001) 51% 1.51, 1.19–1.91, 0.001), respectively, compared lowest quartile. Specific saturation effects for VAI, LAP, identified smoothed fitting, inflection points 3.81 98.55, respectively. revealed that 5.1% 2.8% associations mediated results showed interactions hypertension cardiovascular disease (P 0.05). associated US adults. non-linear, which may be highlights as valuable tools prevention management

Язык: Английский

Процитировано

0
Research Progress on the Relationship between Visceral Obesity and Related Indices and Type 2 Diabetes Mellitus DOI Open Access

娅娟 谭

Journal of Clinical Personalized Medicine, Год журнала: 2025, Номер 04(02), С. 175 - 185

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
The potential role of adipokines and hepatokines in age-related ocular diseases DOI Creative Commons
Stavroula Almpanidou, Ilias D. Vachliotis, Antonis Goulas

и другие.

Metabolism Open, Год журнала: 2025, Номер unknown, С. 100365 - 100365

Опубликована: Апрель 1, 2025

Age-related ocular diseases, including diabetic retinopathy (DR), age-related macular degeneration (AMD), cataract and glaucoma may lead to visual impairment even blindness. Metabolic such as obesity metabolic dysfunction-associated steatotic liver disease (MASLD) have emerged potential risk factors of especially DR. Visceral adiposity has been associated with increased DR AMD in most clinical studies, although body mass index to-date provided conflicting association AMD. In addition, is recognized a factor glaucoma. Similarly obesity, MASLD appears be patients type 1 diabetes mellitus, but probably not those 2 mellitus. A positive between AMD, supported by limited evidence to-date, thus needing further investigation. Altered secretion patterns adipokines (adiponectin, leptin, lipocalin-2, resistin) hepatokines [adropin, fetuin-A, fibroblast growth (FGF)-21, retinol binding protein (RBP)-4] seem disrupt homeostasis contribute the development diseases context MASLD. this regard, novel adipokine-based hepatokine-based therapies added treatment options for future. This narrative review aimed summarize on interconnection specific focus roles mediators these associations.

Язык: Английский

Процитировано

0
Associations Between Lipid Accumulation Product, Visceral Adiposity Index, and Arterial Stiffness: Insights from NHANES 2005-2018 DOI

M. H. Ye,

Di Zhang, Liu Wu

и другие.

Опубликована: Май 13, 2025

Abstract Background Arterial stiffness (AS) serves as a major indicator of vascular aging and is closely associated with cardiovascular disease, diabetes cerebrovascular disorders. While carotid-femoral pulse wave velocity (cfPWV) the gold standard for measuring AS, its clinical use limited by equipment requirements. Estimated (ePWV) offers feasible alternative. Lipid Accumulation Product (LAP) Visceral Adiposity Index (VAI) are newer indices that better capture visceral fat metabolic effects, but their relationship AS remains underexplored. Objective This study examines associations between LAP, VAI, ePWV using NHANES data from 2005–2018, exploring potential threshold effects demographic moderating factors. Methods Data 9,984 adults aged 20–65 were analyzed. was derived age blood pressure. LAP VAI calculated established formulas. Regression models assessed these ePWV, subgroup analyses age, gender, health status. Results Both positively ePWV. showed stronger effect than significant U-shaped relationship, at 2.676. Subgroup analysis revealed in younger women. Conclusion more reliable marker arterial particularly individuals The underscores LAP's utility predicting risk.

Язык: Английский

Процитировано

0