Designing an interoperable solution to support pharmacogenomic-guided prescribing in primary care: an implementer report
BMJ Health & Care Informatics,
Год журнала:
2025,
Номер
32(1), С. e101163 - e101163
Опубликована: Апрель 1, 2025
Study
objectives
Describe
the
implementation
of
an
interoperable
solution
to
support
pharmacogenomic-guided
prescribing
in
primary
care
National
Health
Service,
England.
Methods
We
used
iterative
approach
software
development
going
through
clinical
workflow
mapping,
architecture
design
and
development,
pilot-testing.
Results
configured
a
commercial
health
data
management
platform
store
pharmacogenomic
results
structured
format
created
knowledge
base
guidance.
This
was
deployed
‘as-a-service’
using
open
application
programming
interface
(API)
specification,
allowing
third
parties
receive
guidance
by
querying
service
patient
identifier
medicine
code.
integrated
with
existing
decision
tools
presented
contextual
information
prescribers
within
their
native
electronic
record
(EHR).
Discussion
Pharmacogenomic
will
be
across
settings
have
greatest
utility
at
point
prescribing.
requires
solution,
which
separates
from
applications,
integration
different
EHRs
APIs.
Conclusions
A
vendor-agnostic
standards-based
can
care.
Язык: Английский
Pharmaceutical analysis of inpatient prescriptions: systematic observations of hospital pharmacists' practices in the early user-centered design phase (Preprint)
Опубликована: Сен. 4, 2024
BACKGROUND
The
healthcare
sector's
digital
transformation
has
accelerated,
yet
adverse
drug
events
(ADEs)
continue
to
rise,
posing
significant
clinical
and
economic
challenges.
Clinical
Decision
Support
Systems
(CDSS),
particularly
those
related
medication,
are
crucial
for
improving
patient
care,
identifying
Drug-Related
Problems
(DRPs)
reducing
ADEs.
Hospital
pharmacists
play
a
key
role
in
utilizing
CDSS
management
safety.
Human
Factors
Ergonomics
(HFE)
methods
essential
designing
effective,
human-centered
CDSS.
HFE
involves
three
phases:
exploration,
design,
evaluation,
with
exploration
being
critical
often
overlooked
literature.
For
medication-related
CDSS,
understanding
hospital
pharmacists'
tasks
challenges
is
vital
creating
user-centered
solutions.
OBJECTIVE
aim
of
this
study
explore
the
actual
practices
identify
needs
analyzing
electronic
prescriptions.
This
focuses
on
preliminary
stage
design
pharmacist-centered
METHODS
involved
observing
16
across
five
hospitals
mainland
France,
including
university
hospital,
two
large
general
hospitals,
smaller
specialized
clinic.
Pharmacists
were
selected
regardless
expertise.
observation
method
used
systematic
situ
shadowing
posture,
following
as
they
analyzed
Researchers
recorded
activities,
tools
used,
verbalizations,
behaviors,
interruptions,
using
an
grid.
Data
analysis
focused
modeling
cognitive
work,
categorizing
activities
by
action
type,
specificity,
information
source.
Sequential
time
data
distance
matrices
employed
generate
hierarchical
clustering
similarity
groups
among
analysis.
Each
group
described
its
typical
sequences
covariates.
RESULTS
validated
prescriptions
140
patients,
averaging
5.48
minutes
per
patient.
They
spend
91%
their
searching
rather
than
transmitting
it.
Most
comes
from
list
but
it's
spent
Electronic
Medical
Record
(EMR)
that
dominates
at
heart
Pharmaceutical
interventions
most
frequently
transmitted
last
third
sequence.
pharmaceutical
grouped
into
four
clusters:
A
(22%):
Interventionist
extensive
crossing
various
sources
almost
interventions.
B
(52%):
common
focusing
EMR
biology
results.
C
(13%):
Logistical
analysis,
pharmacy
workflow
medication
circuit.
D
Quick,
trivial
analyses
based
exclusively
CONCLUSIONS
process
complex
multifaceted.
detectives,
accessing
wealth
order
discriminate
DRPs
respond
accordingly.
also
carry
out
different
types
which
lead
require
solutions
exploratory
prerequisite
meeting
challenge
support
pharmacists.
Язык: Английский
Pharmaceutical analysis of inpatient prescriptions: systematic observations of hospital pharmacists' practices in the early user-centered design phase (Preprint)
JMIR Human Factors,
Год журнала:
2024,
Номер
12, С. e65959 - e65959
Опубликована: Ноя. 25, 2024
Abstract
Background
The
health
care
sector’s
digital
transformation
has
accelerated,
yet
adverse
drug
events
continue
to
rise,
posing
significant
clinical
and
economic
challenges.
Clinical
decision
support
systems
(CDSSs),
particularly
those
related
medication,
are
crucial
for
improving
patient
care,
identifying
drug-related
problems,
reducing
events.
Hospital
pharmacists
play
a
key
role
in
using
CDSSs
management
safety.
Human
factors
ergonomics
(HFE)
methods
essential
designing
effective,
human-centered
CDSSs.
HFE
involves
3
phases—exploration,
design,
evaluation—with
exploration
being
critical
often
overlooked
the
literature.
For
medication-related
CDSSs,
understanding
hospital
pharmacists’
tasks
challenges
is
vital
creating
user-centered
solutions.
Objective
This
study
aimed
explore
actual
practices
identify
needs
of
analyzing
electronic
prescriptions.
focused
on
preliminary
stage
design
pharmacist-centered
CDSS.
Methods
involved
observing
16
across
5
hospitals
mainland
France
(a
university
hospital,
2
large
general
hospitals,
smaller
specialized
clinic).
Pharmacists
were
selected
regardless
expertise.
observation
method—systematic
situ
with
shadowing
posture—involved
following
as
they
analyzed
Researchers
recorded
activities,
tools
used,
verbalizations,
behaviors,
interruptions,
an
grid.
Data
analysis
modeling
cognitive
work,
categorizing
activities
by
action
type,
specificity,
information
source.
Sequential
time
data
distance
matrices
used
generate
hierarchical
clustering
similarity
groups
among
analyses.
Each
group
was
described
its
typical
sequences
covariates.
Results
In
total,
validated
prescriptions
140
patients,
averaging
5.48
minutes
per
patient.
They
spend
91%
their
searching
rather
than
transmitting
it.
Most
comes
from
list
prescriptions,
but
it
spent
medical
records
(EMRs)
that
dominates
at
heart
analysis.
Pharmaceutical
interventions
most
frequently
transmitted
last
third
sequence.
pharmaceutical
analyses
grouped
into
4
clusters:
(cluster
A,
22%)
interventionist
extensive
crossing
various
sources
almost
systematic
interventions;
B,
52%)
common
focusing
EMRs
biology
results;
C,
13%)
logistical
analysis,
pharmacy
workflow
medication
circuit;
D,
quick,
trivial
based
exclusively
Conclusions
process
complex
multifaceted.
detectives,
accessing
wealth
discriminate
problems
respond
accordingly.
also
carry
out
different
types
which
lead
require
solutions
exploratory
prerequisite
meeting
challenge
pharmacists.
Язык: Английский