BACKGROUND
Young
people
are
particularly
at
risk
of
developing
mental
health
problems,
a
challenge
exacerbated
by
the
COVID-19
pandemic.
Digital
tools
such
as
apps
and
chatbots
show
promise
in
providing
accessible,
cost-effective,
less
stigmatized
ways
strengthening
their
health.
However,
while
these
interventions
offer
benefits,
they
extend
measures
beyond
traditional
therapeutic
settings
relationships,
which
raises
ethical
concerns
due
to
absence
established
guidelines
regulations.
This
is
notable
for
technologies
incorporating
serious
gaming
elements.
In
addition,
adolescents
sensitive
times
vulnerable
phase,
shows
great
potential
effective
use
preventive
sensitizing
measures.
Considering
lack
an
integration
into
existing
structures
among
many
young
users,
considerations
become
crucial.
OBJECTIVE
scoping
review
aims
build
knowledge
base
on
aspects
implementing
gamified
digital
people.
METHODS
We
conducted
search
research
articles
conference
papers
from
2015
2023
English,
German,
Spanish.
identified
1815
studies
using
unique
combination
keywords
databases
Scopus,
Web
Science,
MEDLINE,
PsycINFO.
After
removing
duplicates
(741/1816,
40.8%),
we
included
total
38
publications
this
following
double
screening
process.
RESULTS
found
that
ethically
relevant
were
discussed
with
regard
(1)
ethics,
(2)
principles
(including
privacy,
accessibility,
empowerment
autonomy,
cultural
social
sensitivity,
co-design),
(3)
groups,
(4)
implications
implementation
facilitators
specific
contexts,
relationship
other
options,
economic
aspects,
embeddedness
technologies).
CONCLUSIONS
prevailing
limited
interpretation
“ethics”
ethics
across
publications.
It
also
discussion
co-design
frequently
viewed
instrumental
terms
vulnerability
mostly
addressed
pragmatically.
Through
concrete
examples
how
researchers
game
designers
thus
far
have
mitigated
challenges
interventions,
illustrates
issues
do
or
not
prompt
diverse
reflections,
mitigation
strategies,
actions.
advocates
be
integrated
ongoing
practice
throughout
all
stages
elements
Healthcare,
Год журнала:
2025,
Номер
13(3), С. 305 - 305
Опубликована: Фев. 2, 2025
Background/Objectives:
Patient
and
public
involvement
engagement
(PPIE)
has
gained
global
recognition
as
an
innovative
healthcare
research
practice.
PPIE
engages
end-users
throughout
the
process,
improving
intervention
effectiveness,
resource
efficiency,
user
satisfaction.
Despite
its
increasing
inclusion
in
studies,
comprehensive
bibliometric
reviews
of
intervention-related
studies
reporting
are
scarce.
This
study
aims
to
conduct
a
analysis
recent
decades
identify
key
worldwide
features,
themes,
trends.
Methods:
The
includes
10,624
relevant
English
articles
published
Web
Science
(WoS)
Core
Collection
up
26
November
2024.
Search
terms
were
selected
based
on
conceptualization,
interventional
types,
related
terms.
Using
WoS
descriptive
CiteSpace,
we
examined
features
identified
major
international
themes
Results:
There
been
significant
increase
number
over
past
five
years,
especially
from
United
States
Kingdom,
with
rise
Asia.
However,
cross-national
collaboration
remains
limited.
Key
include
“community
participation”,
“health
equity”,
“coronary
heart
disease”,
“web-based
patient
empowerment”,
“mental
illness”,
“obesity
prevention”,
growing
interest
“mobile
health”
“digital
health”.
Conclusions:
provides
up-to-date
overview
characteristics
evolving
trends
PPIE.
It
highlights
regions
limited
implementation,
suggests
pathways
for
further
development,
identifies
themes.
offers
researchers
practitioners
valuable
insights
into
tracking
interventions
fostering
collaborations
evidence-based
leading
scholars
institutions
worldwide.
Additionally,
findings
drive
innovations
aimed
at
outcomes.
Frontiers in Digital Health,
Год журнала:
2025,
Номер
7
Опубликована: Фев. 18, 2025
In
the
post-COVID-19
era,
depressive
disorders
among
youth
have
risen
significantly,
creating
an
urgent
need
for
accessible,
cost-effective
mental
health
interventions.
This
study
adapts
Group
Support
Psychotherapy
into
Tele-Support
(TSP)
via
mobile
phones.
It
aims
to
evaluate
its
feasibility,
acceptability,
effectiveness,
and
cost-efficiency
in
addressing
mild
moderate
depression
central
Uganda.
will
use
a
mixed-methods
approach,
starting
with
qualitative
phase
adapt
Guided
by
ecological
theories
Unified
Theory
of
Acceptance
Use
Technology
(UTAUT),
focus
group
discussions
interviews
youth,
professionals,
stakeholders
inform
development
youth-tailored
call
platform
integrated
Rocket
Health
Africa's
telehealth
services.
Data
be
analyzed
using
grounded
theory
MAXQDA
Analytics
Pro
2022
guide
intervention
adaptation.
An
open-label
randomized
controlled
trial
enroll
300
(15-30
years)
from
Kampala,
Uganda,
(TSP).
Participants
TSP
standard
services
(SMHS)
or
SMHS
alone.
Primary
outcomes
include
feasibility
secondary
assessing
cost-effectiveness,
symptom
changes,
social
support.
Intention-to-treat
analysis
structural
equation
modeling
treatment
effects,
complemented
insights
implementation
barriers
facilitators.
protocol
develops
evaluates
resource-limited
settings,
gaps
exacerbated
COVID-19.
Using
user-centered
design
mixed
methods,
it
explores
TSP's
adaptability,
cost-effectiveness
while
like
technology
literacy,
laying
groundwork
accessible
digital
solutions.
PACTR202201684613316.
BACKGROUND
The
Kuamsha
app
was
originally
developed
for
a
two-arm
randomised
controlled
pilot
trial
(the
DoBAt
study),
which
assessed
the
feasibility,
acceptability,
and
initial
efficacy
of
digital
choose-your-own-adventure
style
serious
game
that
delivered
behavioural
activation
(BA)
therapy
to
adolescents
with
depression
in
rural
South
Africa.
OBJECTIVE
This
qualitative
study
explored
role
generative
artificial
intelligence
(AI)
as
novel
method
developing
engaging,
relatable,
relevant
mental
health
content
METHODS
Through
interactive,
exploratory
workshops
focus
group
discussions,
compared
stories,
images,
songs
created
by
AI
those
app,
intervention
without
AI.
RESULTS
Inductive
thematic
analysis
revealed
three
themes:
‘Use
tools
workshop’,
‘Reflections
on
creations
comparison’
‘Thinking
towards
future’.
Adolescents
generally
showed
preference
AI-generated
media
media,
creative
process
an
important
aspect
adolescents.
CONCLUSIONS
highlighted
current
biases
existing
while
also
demonstrating
significant
potential
enhance
‘real-time’
co-design
interventions
incorporating
more
culturally
personalised
content.
BACKGROUND
Low-and
middle-income
countries
(LMICs),
which
bear
a
larger
proportion
of
the
global
mental
illness
burden,
have
been
disproportionately
impacted
by
COVID-19
pandemic
due
to
pre-existing
health
care
system
deficiencies.
The
has
also
led
considerable
increase
in
delivered
through
digital
interventions
(DMHIs),
many
adapted
from
in-person
formats.
There
is
thus
need
examine
their
fidelity
original
format,
along
with
issues
around
usability
and
other
challenges
facilitators
uptake
LMICs.
As
most
DMHIs
developed
high-income
countries,
an
examination
cultural
adaptation
LMIC
settings
will
be
critical.
OBJECTIVE
purpose
this
research
conduct
rapid
scoping
review
available
evidence
for
depression
anxiety,
two
common
disorders,
METHODS
A
was
conducted
following
PRISMA
Extension
Scoping
Reviews
processes
reviews
Tricco
et
al.,
(2017).
PubMed
PsychInfo
databases
were
searched
records
published
between
January
2020,
when
declared
public
emergency,
June
2024
using
search
strategy
consultation
liaison
librarian.
accelerated
development
DMHIs,
timeframe
utilized
capture
recent
literature
that
may
incorporated
new
methods
application.
across
three
domains:
1)
interventions;
2)
or
anxiety;
3)
Data
charted
final
according
intervention
type,
discussions
fidelity,
usability,
adaptation,
RESULTS
total
64
included
analysis,
reasons
exclusion
(e.g.,
focused
on
general,
not
being
DMHI,
LMICs)
reported.
Six
DMHI
platforms
identified:
mobile
app;
telemedicine;
web-based
programs;
4)
videoconferencing;
5)
virtual
reality;
6)
social
media-based
interventions.
Less
than
half
referenced
related
apps.
Challenges
pertained
technological
system,
engagement
issues,
structural
barriers,
concerns
privacy
confidentiality.
Facilitators
widespread
phone
usage,
built
supervision
training
features,
convenience.
Many
emphasized
importance
appropriateness.
CONCLUSIONS
Despite
opportunities
offer
reducing
treatment
gap,
further
work
examining
user
engagement,
required.
Given
rapidly
changing
landscape
delivery
warranted
emergent
changes,
including
potential
harms
unrestrained
ethical
implications
increasing
integration
artificial
intelligence.
CLINICALTRIAL
n/a
Administration and Policy in Mental Health and Mental Health Services Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 19, 2025
Abstract
Peers
are
individuals
with
lived
experience
of
mental
health
challenges
trained
to
provide
support
others
similar
challenges.
Help@Hand
was
a
multi-site
project
that
integrated
peers
into
digital
intervention
(DMHI)
implementation.
This
study
uses
the
Consolidated
Framework
for
Implementation
Research
(CFIR)
frame
reported
by
when
implementing
DMHIs.
Individuals
leading
local
peer
workforce
completed
quarterly
online
surveys
about
perceived
DMHI
Biannual
interviews
probed
details
on
survey-reported
103
and
39
bi-annual
were
collected
from
key
informants
at
11
sites
between
Summer
2020
Fall
2022.
One
challenge
tied
directly
DMHIs;
namely,
device
distribution.
Several
related
Process,
including
recruiting
qualified
integrating
implementations;
communication
collaboration;
translation.
Challenges
in
Individual
domain
included
unclear
roles
multi-tasking
across
various
projects.
Inner
Setting
structural
barriers
hiring
peers,
issues
management,
turnover.
Outer
environmental
technology
readiness,
COVID-19,
decision-making
processes
collaborative,
uneven
sites’
peers.
Funding
uncertainty
bridged
Settings.
Using
CFIR
model
implementation
yielded
useful
lessons,
especially
engaged
as
partners
planning
process.
Successful
will
be
enhanced
ensuring
adequate
readiness
tech-based
interventions,
clear
role
definition,
streamlined
processes,
well-delineated
lines
locally
sites.
Frontiers in Digital Health,
Год журнала:
2025,
Номер
7
Опубликована: Май 15, 2025
Introduction
The
impact
of
personalization
on
user
engagement
and
adherence
in
digital
mental
health
interventions
(DMHIs)
has
been
widely
explored.
However,
there
is
a
lack
clarity
regarding
the
prevalence
its
application,
as
well
dimensions
mechanisms
within
DMHIs
for
adolescents
youth.
Methods
To
understand
how
applied
young
people,
scoping
review
was
conducted.
Empirical
studies
youth
with
depression
anxiety,
published
between
2013
July
2024,
were
extracted
from
PubMed
Scopus.
A
total
67
included
review.
Additionally,
we
expanded
an
existing
framework,
which
originally
classified
into
four
(content,
order,
guidance,
communication)
(user
choice,
provider
rule-based,
machine
learning),
by
incorporating
non-therapeutic
elements.
Results
adapted
framework
includes
therapeutic
content,
communication,
interfaces
(customization
visual
or
interactive
components),
interactivity
(personalization
preferences),
while
retaining
original
mechanisms.
Half
studied
used
only
one
dimension
(51%),
more
than
two-thirds
mechanism.
This
found
that
content
(51%
interventions)
(25%)
favored.
User
choice
most
prevalent
mechanism,
present
60%
interventions.
learning
employed
substantial
number
cases
(30%),
but
no
instances
generative
artificial
intelligence
(AI)
among
studies.
Discussion
findings
suggest
although
elements
are
reported
articles,
their
younger
people's
experience
to
protocols
not
thoroughly
addressed.
Future
may
benefit
AI,
adhering
standard
clinical
research
practices,
further
personalize
experiences.
Journal of Medical Internet Research,
Год журнала:
2024,
Номер
26, С. e51376 - e51376
Опубликована: Сен. 4, 2024
Background
Digital
mental
health
interventions
(DMHIs)
are
increasingly
recognized
as
potential
solutions
for
adolescent
health,
particularly
in
low-
and
middle-income
countries
(LMICs).
The
United
Nations’
Sustainable
Development
Goals
universal
coverage
instrumental
tools
achieving
all.
Within
this
context,
understanding
the
design,
evaluation,
well
barriers
facilitators
impacting
engagement
with
care
through
DMHIs
is
essential.
Objective
This
scoping
review
aims
to
provide
insights
into
current
landscape
of
adolescents
LMICs.
Methods
Joanna
Briggs
Institute
methodology
was
used,
following
recommendations
PRISMA-ScR
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
Extension
Scoping
Reviews).
Our
search
strategy
incorporated
3
key
concepts:
population
"adolescents,"
concept
"digital
interventions,"
context
"LMICs."
We
adapted
various
databases,
including
ACM
Library,
APA
PsycINFO,
Cochrane
Google
Scholar
(including
gray
literature),
IEEE
Xplore,
ProQuest,
PubMed
(NLM),
ScienceDirect,
Scopus,
Web
Science.
articles
were
screened
against
a
specific
eligibility
criterion
from
January
2019
March
2024.
Results
analyzed
20
papers
focusing
on
conditions
among
adolescents,
such
depression,
well-being,
anxiety,
stigma,
self-harm,
suicide
ideation.
These
delivered
diverse
formats,
group
delivery
self-guided
interventions,
support
professionals
or
involving
lay
professionals.
study
designs
evaluation
encompassed
range
methodologies,
randomized
controlled
trials,
mixed
methods
studies,
feasibility
studies.
Conclusions
While
there
have
been
notable
advancements
LMICs,
research
base
remains
limited.
Significant
knowledge
gaps
persist
regarding
long-term
clinical
benefits,
maturity
readiness
LMIC
digital
infrastructure,
cultural
appropriateness,
cost-effectiveness
across
heterogeneous
settings.
Addressing
these
necessitates
large-scale,
co-designed,
culturally
sensitive
DMHI
trials.
Future
work
should
address
this.
JMIR Serious Games,
Год журнала:
2024,
Номер
12, С. e64488 - e64488
Опубликована: Ноя. 28, 2024
Background
Young
people
are
particularly
at
risk
of
developing
mental
health
problems,
a
challenge
exacerbated
by
the
COVID-19
pandemic.
Digital
tools
such
as
apps
and
chatbots
show
promise
in
providing
accessible,
cost-effective,
less
stigmatized
ways
strengthening
their
health.
However,
while
these
interventions
offer
benefits,
they
extend
measures
beyond
traditional
therapeutic
settings
relationships,
which
raises
ethical
concerns
due
to
absence
established
guidelines
regulations.
This
is
notable
for
technologies
incorporating
serious
gaming
elements.
In
addition,
adolescents
sensitive
times
vulnerable
phase,
shows
great
potential
effective
use
preventive
sensitizing
measures.
Considering
lack
an
integration
into
existing
structures
among
many
young
users,
considerations
become
crucial.
Objective
scoping
review
aims
build
knowledge
base
on
aspects
implementing
gamified
digital
people.
Methods
We
conducted
search
research
articles
conference
papers
from
2015
2023
English,
German,
Spanish.
identified
1815
studies
using
unique
combination
keywords
databases
Scopus,
Web
Science,
MEDLINE,
PsycINFO.
After
removing
duplicates
(741/1816,
40.8%),
we
included
total
38
publications
this
following
double
screening
process.
Results
found
that
ethically
relevant
were
discussed
with
regard
(1)
ethics,
(2)
principles
(including
privacy,
accessibility,
empowerment
autonomy,
cultural
social
sensitivity,
co-design),
(3)
groups,
(4)
implications
implementation
facilitators
specific
contexts,
relationship
other
options,
economic
aspects,
embeddedness
technologies).
Conclusions
prevailing
limited
interpretation
“ethics”
ethics
across
publications.
It
also
discussion
co-design
frequently
viewed
instrumental
terms
vulnerability
mostly
addressed
pragmatically.
Through
concrete
examples
how
researchers
game
designers
thus
far
have
mitigated
challenges
interventions,
illustrates
issues
do
or
not
prompt
diverse
reflections,
mitigation
strategies,
actions.
advocates
be
integrated
ongoing
practice
throughout
all
stages
elements
JMIR Serious Games,
Год журнала:
2024,
Номер
12, С. e59381 - e59381
Опубликована: Дек. 19, 2024
Background
Many
adolescents
in
Uganda
are
affected
by
common
mental
disorders,
but
only
a
few
affordable
treatment
options
available.
Digital
health
interventions
offer
promising
opportunities
to
reduce
these
large
gaps,
specifically
tailored
for
Ugandan
limited.
Objective
This
study
aimed
determine
the
feasibility
and
acceptability
of
Kuamsha
program,
an
intervention
delivered
through
gamified
app
with
low-intensity
telephonic
guidance,
as
way
promote
among
from
general
population
Uganda.
Methods
A
3-month
pre-post
single-arm
trial
was
conducted
aged
between
15
19
years
living
Wakiso
District,
Central
The
coproduced
site
ensure
that
it
culturally
acceptable.
were
evaluated
using
explanatory
sequential
mixed
methods
approach.
Feasibility
assessed
collecting
data
on
retention
rates
adherence
rates.
Acceptability
questionnaire
in-depth
interviews
participants
following
conclusion
period.
As
secondary
objective,
we
explored
changes
participants’
before
after
intervention.
Results
total
31
recruited
study.
showed
high
levels
acceptability.
Trial
exceeded
90%,
≥80%.
These
results,
against
our
predefined
progression
criteria,
indicate
successful
study,
all
criteria
exceeding
thresholds
necessary
progress
larger
trial.
App
engagement
metrics,
such
time
spent
modules
completed,
existing
literature
benchmarks,
many
continued
use
In-depth
responses
revealed
levels.
Depressive
symptoms
trended
toward
reduction
(mean
difference:
1.41,
95%
CI
–0.60
3.42,
Cohen
d=0.30),
although
this
not
statistically
significant
(P=.16).
Supporting
trend,
also
observed
proportion
moderate
depressive
32%
(10/31)
17%
(5/29)
intervention,
change
(P=.10).
Conclusions
presents
evidence
support
program
feasible
acceptable
digital
fully
powered
randomized
controlled
is
needed
assess
its
effectiveness
improving
adolescents’
health.
