The Effect of a Nature-Based Gel on Gingival Inflammation and the Proteomic Profile of Crevicular Fluid: A Randomized Clinical Trial DOI Creative Commons
Luciene Cristina Figueiredo, Bruno Bueno‐Silva,

Giovanna Denúncio

и другие.

Gels, Год журнала: 2024, Номер 10(12), С. 772 - 772

Опубликована: Ноя. 27, 2024

Evidence has shown the clear positive effects of nature-based products on biofilm control and improved gingival health. However, most studies have used in vitro models, tested single natural components, or not evaluated proteomic changes after treatment. This double-blind, parallel, randomized, controlled clinical trial benefits a gel controlling inflammation its crevicular fluid (GCF) profile. Gingivitis patients were distributed into following groups: (1) containing propolis, aloe vera, green tea, cranberry, calendula (n = 10); (2) control—conventional toothpaste 10). GCF was collected by means liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS). At 3 months, groups showed similar (p < 0.05). A total 480 proteins identified across all groups. In pooled comparison both at time points, exclusive (78) (21) The for mainly acted wound healing, those immune system processes. achieved outcomes to conventional toothpaste. markedly changed profile treatment, showing associated host response.

Язык: Английский

Propolis nanoemulsion extract from celebes stingless bee (Tetragonula biroi) phytochemistry and antibacterial analysis to periodontopathogen bacteria DOI

Nadya Rafika Amalia,

Theresia Indah Budhy, Rini Devijаnti Ridwаn

и другие.

Journal of Oral Biology and Craniofacial Research, Год журнала: 2025, Номер 15(3), С. 576 - 584

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

1

Green Tea: A Novel Perspective on the Traditional Plant’s Potential in Managing Periodontal Diseases DOI Creative Commons
Magdalena Paczkowska-Walendowska,

Jan Grzegorzewski,

Jakub Kwiatek

и другие.

Pharmaceuticals, Год журнала: 2025, Номер 18(3), С. 409 - 409

Опубликована: Март 14, 2025

Green tea (Camellia sinensis) exhibits significant potential in oral health due to its antioxidant, anti-inflammatory, and antimicrobial properties. This review explores role managing periodontal disease, a common condition characterized by inflammation, microbial imbalances, tissue destruction. The primary bioactive components, particularly epigallocatechin-3-gallate (EGCG), contribute green tea’s therapeutic effects inhibiting bacterial adhesion, modulating inflammatory pathways, reducing oxidative stress. Clinical studies suggest improves pocket depth, bleeding. It can serve as an adjunct conventional therapies, including scaling root planing, be incorporated into care products such mouthwashes dentifrices. Furthermore, presents natural alternative chemical agents like chlorhexidine, potentially mitigating side addressing concerns about antibiotic resistance. However, efficacy remains moderate compared established treatments, highlighting the need for further research optimize formulation applications. represents sustainable biocompatible approach therapy, supporting integration preventive strategies.

Язык: Английский

Процитировано

0

Does crocin create new hope for the treatment of oral problems? A focus on periodontitis DOI
Atefe Rekabi,

A Ram,

Ahmad Nazari

и другие.

Molecular Biology Reports, Год журнала: 2024, Номер 51(1)

Опубликована: Янв. 28, 2024

Язык: Английский

Процитировано

2

The Effect of a Nature-Based Gel on Gingival Inflammation and the Proteomic Profile of Crevicular Fluid: A Randomized Clinical Trial DOI Creative Commons
Luciene Cristina Figueiredo, Bruno Bueno‐Silva,

Giovanna Denúncio

и другие.

Gels, Год журнала: 2024, Номер 10(12), С. 772 - 772

Опубликована: Ноя. 27, 2024

Evidence has shown the clear positive effects of nature-based products on biofilm control and improved gingival health. However, most studies have used in vitro models, tested single natural components, or not evaluated proteomic changes after treatment. This double-blind, parallel, randomized, controlled clinical trial benefits a gel controlling inflammation its crevicular fluid (GCF) profile. Gingivitis patients were distributed into following groups: (1) containing propolis, aloe vera, green tea, cranberry, calendula (n = 10); (2) control—conventional toothpaste 10). GCF was collected by means liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS). At 3 months, groups showed similar (p < 0.05). A total 480 proteins identified across all groups. In pooled comparison both at time points, exclusive (78) (21) The for mainly acted wound healing, those immune system processes. achieved outcomes to conventional toothpaste. markedly changed profile treatment, showing associated host response.

Язык: Английский

Процитировано

0