Asian Journal of Dental and Health Sciences,
Год журнала:
2025,
Номер
5(1), С. 1 - 4
Опубликована: Март 15, 2025
Anemia
during
pregnancy
is
a
significant
public
health
challenge,
affecting
maternal
well-being
and
fetal
development.
Among
the
most
common
causes
are
iron
deficiency
anemia
(IDA)
thalassemia
trait
(TT),
conditions
requiring
distinct
management
strategies.
Accurate
differentiation
between
these
critical,
as
misdiagnosis
can
lead
to
suboptimal
treatment
outcomes.
The
Mentzer
Index,
calculated
by
dividing
mean
corpuscular
volume
(MCV)
red
blood
cell
(RBC)
count,
offers
simple
reliable
tool
for
distinguishing
IDA
TT,
especially
in
resource-limited
settings.
This
review
explores
utility
of
Index
improving
diagnosis
pregnancy.
By
analyzing
routine
complete
count
(CBC)
results,
allows
initial
differentiation,
facilitating
timely
appropriate
interventions.
A
value
≥13
indicates
IDA,
guiding
clinicians
toward
supplementation,
while
<13
suggests
prompting
further
investigations
genetic
counseling.
approach
reduces
unnecessary
interventions,
improves
diagnostic
accuracy,
ensures
tailored
management,
mitigating
complications
such
preterm
birth,
low
birth
weight,
morbidity.
Keywords:
pregnancy,
anemia,
deficiency,
Asian Journal of Dental and Health Sciences,
Год журнала:
2025,
Номер
5(1), С. 15 - 19
Опубликована: Март 15, 2025
Anemia
remains
a
common
and
critical
health
issue
in
high-risk
pregnancies,
leading
to
adverse
outcomes
for
both
the
mother
fetus,
including
preterm
birth,
low
birth
weight,
maternal
fatigue.
Differentiating
between
two
most
causes
of
microcytic
anemia—iron
deficiency
anemia
(IDA)
thalassemia
trait
(TT)—is
essential
appropriate
management.
The
Mentzer
Index,
calculated
by
dividing
mean
corpuscular
volume
(MCV)
red
blood
cell
(RBC)
count,
has
been
proposed
as
simple
effective
tool
distinguish
these
conditions.
This
review
explores
role
Index
screening
management,
particularly
where
timely
accurate
diagnosis
is
crucial
improving
outcomes.
application
pregnancies
offers
quick
cost-effective
method
clinicians
identify
whether
likely
due
IDA
or
TT.
A
score
below
13
typically
suggests
trait,
while
scores
above
generally
point
toward
iron
anemia.
While
useful,
not
definitive
on
its
own
should
be
complemented
other
diagnostic
tests,
such
hemoglobin
electrophoresis,
serum
ferritin,
transferrin
saturation,
confirm
underlying
cause
By
integrating
methods,
healthcare
providers
can
better
tailor
treatment
plans,
ensuring
that
women
with
receive
supplementation
avoiding
overload
those
trait.
Keywords:
screening,
anemia,
International Journal of Medical Sciences and Pharma Research,
Год журнала:
2025,
Номер
11(1), С. 40 - 44
Опубликована: Март 15, 2025
Pregnancy-related
anemia
is
a
common
and
significant
health
concern
that
can
impact
maternal
fetal
outcomes.
Hematopoietic
growth
factors,
including
erythropoietin
(EPO),
granulocyte-colony
stimulating
factor
(G-CSF),
thrombopoietin
(TPO),
are
essential
regulators
of
hematopoiesis,
influencing
red
blood
cell,
white
platelet
production.
This
review
explores
the
role
these
factors
in
pregnancy-related
anemia,
examining
how
they
regulate
erythropoiesis
immune
responses
during
pregnancy.
The
article
also
addresses
therapeutic
potential
managing
pregnant
women,
highlighting
their
possible
use
cases
where
conventional
treatments,
such
as
iron
supplementation,
may
be
insufficient.
Erythropoietin,
primarily
produced
by
kidneys,
main
involved
cell
During
pregnancy,
increased
EPO
production
supports
expanding
volume
oxygen
demands
fetus.
However,
deficiency
other
nutritional
deficiencies
limit
effectiveness
addressing
anemia.
Additionally,
G-CSF,
neutrophil
production,
have
supporting
enhancing
function
reducing
infection
risks
women
with
Thrombopoietin,
dysfunction
conditions
like
preeclampsia.
Keywords:
erythropoiesis,
management,
International Journal of Medical Sciences and Pharma Research,
Год журнала:
2025,
Номер
11(1), С. 28 - 33
Опубликована: Март 15, 2025
Anemia
is
a
prevalent
condition
during
pregnancy,
often
leading
to
significant
health
consequences
for
both
the
mother
and
fetus.
One
of
major
concerns
associated
with
anemia
in
pregnant
women
its
impact
on
immune
system.
Iron
deficiency,
most
common
cause
anemia,
can
impair
cell
function,
reduce
body’s
ability
respond
infections,
alter
inflammatory
responses.
This
review
explores
effects
maternal
function
highlighting
disruptions
innate
adaptive
immunity
mechanisms
involved,
such
as
altered
cytokine
production
dysregulation.
The
system
undergoes
considerable
changes
pregnancy
balance
fetal
protection,
disrupt
this
delicate
equilibrium.
Anemia’s
cells,
particularly
neutrophils,
macrophages,
T
lymphocytes,
compromises
defense
against
infections.
Moreover,
anemia-associated
inflammation
promote
pro-inflammatory
state,
contributing
complications
like
preeclampsia,
gestational
diabetes,
preterm
labor.
These
dysregulations
may
also
affect
development,
increasing
risk
neonatal
infections
or
immune-related
disorders.
Keywords:
Anemia,
Immune
System,
Pregnancy,
Inflammation,
Immunity
International Journal of Medical Sciences and Pharma Research,
Год журнала:
2025,
Номер
11(1), С. 8 - 13
Опубликована: Март 15, 2025
Maternal
anemia
is
a
significant
health
concern
during
pregnancy,
with
various
causes
contributing
to
its
onset.
In
particular,
infectious
diseases
such
as
malaria
and
HIV
can
exacerbate
anemia,
leading
increased
risks
for
both
the
mother
fetus.
This
review
explores
complex
relationship
between
maternal
focusing
on
pathophysiology,
clinical
implications,
diagnostic
approaches,
management
strategies
associated
HIV.
The
combined
effect
of
infections
lead
severe
complications
preterm
birth,
low
birth
weight,
morbidity,
making
early
detection
targeted
interventions
essential
optimal
outcomes.
Infectious
like
contribute
through
direct
indirect
mechanisms.
Malaria,
instance,
leads
destruction
red
blood
cells,
while
HIV-related
often
linked
bone
marrow
suppression
chronic
inflammation.
These
worsen
body’s
nutritional
status,
further
deficiencies
in
vitamins
minerals,
including
iron,
folate,
vitamin
B12.
Both
conditions
require
specific
address
underlying
infection
treat
effectively.
areas
high
rates
HIV,
comprehensive
approach
care
vital
mitigate
complications.
Keywords:
diseases,
malaria,
Asian Journal of Dental and Health Sciences,
Год журнала:
2025,
Номер
5(1), С. 25 - 29
Опубликована: Март 15, 2025
Maternal
anemia
is
a
prevalent
condition
that
poses
significant
health
risks
to
both
mothers
and
their
infants.
Accurate
timely
diagnosis
crucial
for
effective
management,
particularly
in
differentiating
between
iron
deficiency
(IDA)
thalassemia
trait
(TT),
two
common
causes
of
microcytic
during
pregnancy.
The
Mentzer
Index
(MI),
simple
cost-effective
diagnostic
tool,
used
distinguish
these
conditions
by
calculating
the
ratio
mean
corpuscular
volume
(MCV)
red
blood
cell
(RBC)
count.
This
review
explores
utility
maternal
diagnosis,
highlighting
its
role
early
detection
management.
offers
rapid,
straightforward
approach
identifying
underlying
cause
pregnant
women,
especially
resource-limited
settings.
A
result
MI
<
13
suggests
trait,
while
>
indicative
anemia.
Early
differentiation
allows
targeted
interventions,
such
as
supplementation
IDA,
avoids
unnecessary
therapy
TT,
thus
optimizing
patient
outcomes.
Despite
advantages,
has
limitations,
cases
mixed
or
when
other
forms
are
present.
In
instances,
further
tests
necessary
an
accurate
diagnosis.
Keywords:
Index,
Anemia,
Iron
Deficiency,
Thalassemia,
Diagnosis
Asian Journal of Dental and Health Sciences,
Год журнала:
2025,
Номер
5(1), С. 11 - 14
Опубликована: Март 15, 2025
Maternal
anemia
is
a
significant
health
concern
during
pregnancy,
as
it
poses
risks
for
both
maternal
and
fetal
well-being.
Two
common
causes
of
microcytic
in
pregnant
women
are
iron
deficiency
(IDA)
thalassemia
trait
(TT).
Distinguishing
between
these
conditions
crucial,
their
management
differs
substantially.
The
Mentzer
Index
(MI),
simple
diagnostic
tool,
commonly
used
to
differentiate
IDA
TT
based
on
the
mean
corpuscular
volume
(MCV)
red
blood
cell
(RBC)
count.
However,
while
MI
widely
due
its
simplicity
cost-effectiveness,
accuracy
can
be
influenced
by
various
factors,
including
presence
mixed
anemia,
laboratory
errors,
coexisting
conditions.
This
review
explores
challenges
evaluates
role
clinical
practice.
We
discuss
how
helpful
initial
screening,
particularly
resource-limited
settings,
but
highlight
limitations
cases
complex
such
when
coexists
with
deficiency.
also
examine
complementary
methods,
serum
ferritin,
hemoglobin
electrophoresis,
genetic
testing,
which
improve
guide
treatment
decisions.
Keywords:
Index,
challenges,
Asian Journal of Dental and Health Sciences,
Год журнала:
2025,
Номер
5(1), С. 1 - 4
Опубликована: Март 15, 2025
Anemia
during
pregnancy
is
a
significant
public
health
challenge,
affecting
maternal
well-being
and
fetal
development.
Among
the
most
common
causes
are
iron
deficiency
anemia
(IDA)
thalassemia
trait
(TT),
conditions
requiring
distinct
management
strategies.
Accurate
differentiation
between
these
critical,
as
misdiagnosis
can
lead
to
suboptimal
treatment
outcomes.
The
Mentzer
Index,
calculated
by
dividing
mean
corpuscular
volume
(MCV)
red
blood
cell
(RBC)
count,
offers
simple
reliable
tool
for
distinguishing
IDA
TT,
especially
in
resource-limited
settings.
This
review
explores
utility
of
Index
improving
diagnosis
pregnancy.
By
analyzing
routine
complete
count
(CBC)
results,
allows
initial
differentiation,
facilitating
timely
appropriate
interventions.
A
value
≥13
indicates
IDA,
guiding
clinicians
toward
supplementation,
while
<13
suggests
prompting
further
investigations
genetic
counseling.
approach
reduces
unnecessary
interventions,
improves
diagnostic
accuracy,
ensures
tailored
management,
mitigating
complications
such
preterm
birth,
low
birth
weight,
morbidity.
Keywords:
pregnancy,
anemia,
deficiency,
