Sleep in the Intensive Care Unit

American Journal of Respiratory and Critical Care Medicine, Год журнала: 2015, Номер 191(7), С. 731 - 738

Опубликована: Янв. 16, 2015

Section:ChooseTop of pageAbstract <

Язык: Английский

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Evening Chronotype Is Associated With Metabolic Disorders and Body Composition in Middle-Aged Adults

The Journal of Clinical Endocrinology & Metabolism, Год журнала: 2015, Номер 100(4), С. 1494 - 1502

Опубликована: Апрель 1, 2015

Chronotype is a trait determining individual circadian preference in behavioral and biological rhythm relative to external light-dark cycle. However, little known about the relationship between chronotype metabolic disorders. The aim of this study was examine whether late related abnormalities body composition middle-aged adults, independent sleep duration lifestyle. A total 1620 participants aged 47–59 years were recruited from Korean Genome Epidemiology Study. assessed by Morningness-Eveningness Questionnaire. Associations with diabetes, syndrome, sarcopenia, visceral obesity analyzed. All underwent oral glucose tolerance test, measured dual energy x-ray absorptiometry. Visceral designated as fat area, abdominal computed tomography, >100 cm2. classified morning 29.6% subjects, evening 5.9%, neither nor 64.5%. Evening type, when compared significantly associated diabetes (odds ratio [OR], 1.73; 95% confidence interval [CI], 1.01–2.95), syndrome (OR, 1.74; CI, 1.05–2.87), sarcopenia 3.16; 1.36–7.33) after adjusting for confounding factors. Gender differences associations evident. In men, type 2.98; 1.39–6.39) 3.89; 1.33–11.33). Only women 2.22; 1.11–4.43). At population level, independently sarcopenia. These results support importance rhythms regulation.

Язык: Английский

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Impact of circadian misalignment on energy metabolism during simulated nightshift work

Proceedings of the National Academy of Sciences, Год журнала: 2014, Номер 111(48), С. 17302 - 17307

Опубликована: Ноя. 17, 2014

Eating at a time when the internal circadian clock promotes sleep is novel risk factor for weight gain and obesity, yet little known about mechanisms by which misalignment leads to metabolic dysregulation in humans. We studied 14 adults 6-d inpatient simulated shiftwork protocol quantified changes energy expenditure, macronutrient utilization, appetitive hormones, sleep, phase during day versus nightshift work. found that total daily expenditure increased ∼4% on transition first nightshift, consisted of an afternoon nap extended wakefulness, whereas decreased ∼3% each second third days, daytime followed nighttime wakefulness. Contrary expectations, ∼12-16% scheduled opportunities despite disturbed sleep. The thermic effect feeding also response late dinner nightshift. Total fat utilization contrary carbohydrate protein were reduced day. Ratings hunger days decreases 24-h levels satiety hormones leptin peptide-YY. Findings suggest schedules represent contributing humans working eating biological night, promoting may increase obesity.

Язык: Английский

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Sleep, circadian rhythm, and gut microbiota

Sleep Medicine Reviews, Год журнала: 2020, Номер 53, С. 101340 - 101340

Опубликована: Май 13, 2020

Язык: Английский

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Circadian System and Glucose Metabolism: Implications for Physiology and Disease

Trends in Endocrinology and Metabolism, Год журнала: 2016, Номер 27(5), С. 282 - 293

Опубликована: Апрель 11, 2016

Язык: Английский

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