Background:
The
American
Heart
Association,
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
diet,
weight)
factors
(cholesterol,
blood
pressure,
glucose
control)
that
contribute
health.
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
congenital
rhythm
disorders,
subclinical
atherosclerosis,
coronary
failure,
valvular
venous
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
Methods:
through
its
Epidemiology
Prevention
Statistics
Committee,
continuously
monitors
evaluates
sources
stroke
United
States
provide
current
information
available
annual
review
published
literature
year
before
writing.
2023
is
product
full
year’s
worth
effort
2022
by
dedicated
volunteer
clinicians
scientists,
committed
government
professionals,
Association
staff
members.
strives
further
understand
help
heal
problems
inflicted
structural
racism,
public
crisis
can
significantly
damage
mental
perpetuate
disparities
access
education,
income,
housing,
several
other
vital
healthy
lives.
This
edition
includes
additional
COVID-19
(coronavirus
2019)
publications,
as
well
monitoring
benefits
population,
an
enhanced
focus
equity
across
key
domains.
Results:
Each
chapters
focuses
different
topic
statistics.
Conclusions:
represents
critical
resource
for
lay
public,
policymakers,
media
clinicians,
care
administrators,
researchers,
advocates,
others
seeking
best
these
conditions.
The
American
Heart
Association,
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
diet,
weight)
factors
(cholesterol,
blood
pressure,
glucose
control)
that
contribute
health.
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
congenital
rhythm
disorders,
subclinical
atherosclerosis,
coronary
failure,
valvular
venous
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
BACKGROUND:
The
American
Heart
Association
(AHA),
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
nutrition,
sleep,
obesity)
factors
(cholesterol,
blood
pressure,
glucose
control,
metabolic
syndrome)
that
contribute
health.
AHA
Disease
Stroke
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
brain
health,
complications
pregnancy,
kidney
congenital
rhythm
disorders,
sudden
cardiac
arrest,
subclinical
atherosclerosis,
coronary
cardiomyopathy,
failure,
valvular
venous
thromboembolism,
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
METHODS:
AHA,
through
its
Epidemiology
Prevention
Statistics
Committee,
continuously
monitors
evaluates
sources
stroke
United
States
globally
provide
current
information
available
annual
review
published
literature
year
before
writing.
2024
is
product
full
year’s
worth
effort
2023
by
dedicated
volunteer
clinicians
scientists,
committed
government
professionals,
staff
members.
strives
further
understand
help
heal
problems
inflicted
structural
racism,
public
crisis
can
significantly
damage
mental
perpetuate
disparities
access
education,
income,
housing,
several
other
vital
healthy
lives.
This
edition
includes
additional
global
data,
as
well
monitoring
benefits
population,
an
enhanced
focus
equity
across
key
domains.
RESULTS:
Each
chapters
focuses
different
topic
statistics.
CONCLUSIONS:
represents
critical
resource
for
lay
public,
policymakers,
media
clinicians,
care
administrators,
researchers,
advocates,
others
seeking
best
these
conditions.
Nature Reviews Endocrinology,
Год журнала:
2021,
Номер
17(3), С. 135 - 149
Опубликована: Янв. 21, 2021
Obesity
and
impaired
metabolic
health
are
established
risk
factors
for
the
non-communicable
diseases
(NCDs)
type
2
diabetes
mellitus,
cardiovascular
disease,
neurodegenerative
diseases,
cancer
nonalcoholic
fatty
liver
otherwise
known
as
associated
disease
(MAFLD).
With
worldwide
spread
of
severe
acute
respiratory
syndrome
coronavirus
(SARS-CoV-2),
obesity
also
emerged
important
determinants
2019
(COVID-19).
Furthermore,
novel
findings
indicate
that
specifically
visceral
characteristics
such
hyperglycaemia,
hypertension
subclinical
inflammation
with
a
high
COVID-19.
In
this
Review,
we
highlight
how
increase
complications
mortality
in
We
summarize
consequences
SARS-CoV-2
infection
organ
function
NCDs.
addition,
discuss
data
indicating
COVID-19
pandemic
could
have
serious
epidemic.
As
both
accelerators
COVID-19,
might
adversely
influence
efficacy
vaccines,
propose
strategies
prevention
treatment
on
clinical
population
level,
particularly
while
is
present.
This
Review
highlights
(COVID-19)
summarizes
function.
there
discussion
implications
pandemic.
BMJ Open,
Год журнала:
2021,
Номер
11(10), С. e052777 - e052777
Опубликована: Окт. 1, 2021
We
conducted
a
systematic
literature
review
and
meta-analysis
of
observational
studies
to
investigate
the
association
between
diabetes,
hypertension,
body
mass
index
(BMI)
or
smoking
with
risk
death
in
patients
COVID-19
estimate
proportion
deaths
attributable
these
conditions.
Cardiovascular Research,
Год журнала:
2021,
Номер
117(14), С. 2705 - 2729
Опубликована: Сен. 11, 2021
The
cardiovascular
system
is
significantly
affected
in
coronavirus
disease-19
(COVID-19).
Microvascular
injury,
endothelial
dysfunction,
and
thrombosis
resulting
from
viral
infection
or
indirectly
related
to
the
intense
systemic
inflammatory
immune
responses
are
characteristic
features
of
severe
COVID-19.
Pre-existing
disease
load
linked
myocardial
injury
worse
outcomes.
vascular
response
cytokine
production
interaction
between
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2)
angiotensin-converting
enzyme
2
receptor
may
lead
a
significant
reduction
cardiac
contractility
subsequent
dysfunction.
In
addition,
considerable
proportion
patients
who
have
been
infected
with
SARS-CoV-2
do
not
fully
recover
continue
experience
large
number
symptoms
post-acute
complications
absence
detectable
infection.
This
conditions
often
referred
as
'post-acute
COVID-19'
multiple
causes.
Viral
reservoirs
lingering
fragments
RNA
proteins
contribute
condition.
Systemic
COVID-19
has
potential
increase
fibrosis
which
turn
impair
remodelling.
Here,
we
summarize
current
knowledge
sequelae
As
pandemic
continues
new
variants
emerge,
can
advance
our
underlying
mechanisms
only
by
integrating
understanding
pathophysiology
corresponding
clinical
findings.
Identification
biomarkers
complications,
development
effective
treatments
for
crucial
importance.
European Respiratory Journal,
Год журнала:
2021,
Номер
59(3), С. 2101209 - 2101209
Опубликована: Авг. 12, 2021
Individual
case
series
and
cohort
studies
have
reported
conflicting
results
in
people
with
asthma
on
the
vulnerability
to
risk
of
mortality
from
coronavirus
disease
2019
(COVID-19).Are
at
a
higher
being
infected
or
hospitalised
poorer
clinical
outcomes
COVID-19?A
systematic
review
meta-analysis
based
five
main
databases
including
World
Health
Organization
COVID-19
database
between
1
December
11
July
2021
control
(non-asthma)
group
was
conducted.
Prevalence
ratios
were
pooled
using
Sidik-Jonkman
random-effects
meta-analyses.51
an
8.08%
(95%
CI
6.87-9.30%)
prevalence
among
positive
cases.
The
0.83
0.73-0.95,
p=0.01)
for
acquiring
COVID-19;
1.18
0.98-1.42,
p=0.08)
hospitalisation;
1.21
0.97-1.51,
p=0.09)
intensive
care
unit
(ICU)
admission;
1.06
0.82-1.36,
p=0.65)
ventilator
use;
0.94
0.76-1.17,
p=0.58)
asthma.
Subgroup
analyses
by
continent
revealed
significant
difference
COVID-19,
ICU
admission,
use
death
continents.The
severe
acute
respiratory
syndrome
2
reduced
compared
non-asthma
group.
No
statistically
differences
hospitalisation,
admission
found
groups.
showed
America,
Europe
Asia.
Additional
are
required
confirm
this
profile,
particularly
Africa
South
where
few
originate.
Frontiers in Endocrinology,
Год журнала:
2021,
Номер
12
Опубликована: Март 31, 2021
The
pandemic
of
coronavirus
disease
(COVID-19),
caused
by
severe
acute
respiratory
syndrome
2
(SARS-CoV-2),
has
involved
more
than
one
hundred
million
individuals,
including
two
deaths.
Diabetes
represents
the
most
prevalent
chronic
conditions
worldwide
and
significantly
increases
risk
hospitalization
death
in
COVID-19
patients.
In
this
review,
we
discuss
prevalence,
pathophysiological
mechanisms,
outcomes
infection
people
with
diabetes.
We
propose
a
rationale
for
using
drugs
prescribed
patients
diabetes
some
pragmatic
clinical
recommendations
to
deal
kind
patient.
Obesity
and
diabetes
are
established
comorbidities
for
COVID-19.
Adipose
tissue
demonstrates
high
expression
of
ACE2
which
SARS-
CoV-2
exploits
to
enter
host
cells.
This
makes
adipose
a
reservoir
SARS-CoV-2
viruses
thus
increases
the
integral
viral
load.
Acute
infection
results
in
downregulation.
relative
deficiency
can
lead
disturbances
other
systems
controlled
by
ACE2,
including
renin-angiotensin
system.
will
be
further
increased
case
pre-conditions
with
already
compromised
functioning
these
systems,
such
as
patients
obesity
diabetes.
Here,
we
propose
that
interactions
virally-induced
and/or
leads
synergistic
impairment
endothelial
gut
barrier
function.
The
appearance
bacteria
their
products
lungs
obese
diabetic
promotes
between
bacterial
pathogens,
resulting
more
severe
lung
injury
