Journal of obstetrics and women s diseases,
Год журнала:
2025,
Номер
73(6), С. 101 - 115
Опубликована: Янв. 30, 2025
Background:
Type
1
diabetes
mellitus
and
endometriosis
significantly
reduce
the
quality
of
patient’s
life
hinder
implementation
reproductive
plans.
Studying
features
clinical
course
in
patients
with
type
will
help
development
new
effective
safe
therapeutic
strategies
diagnostic
methods.
Aim:
The
aim
this
study
was
to
analyze
diseases,
hormonal
status
blood
vitamin
D
(25-hydroxycalciferol)
levels
combined
endometriosis.
Materials
methods:
This
prospective
included
339
women,
whom
79
were
(mean
age
31.7
±
5.0
years),
51
31.4
3.7
209
30.2
4.9
years).
control
group
consisted
31
healthy
women
age.
immunochemiluminescent
method
used
determine
serum
anti-Müllerian
hormone,
follicle-stimulating
luteinizing
prolactin,
estradiol
(days
2–5
menstrual
cycle),
progesterone
20–23
cycle)
during
three
consecutive
cycles,
level
glycated
hemoglobin
also
studied
mellitus.
diagnosis
all
confirmed
based
on
laparoscopic
surgery
verification
by
histological
examination.
Results:
When
assessing
gonadotropins,
hormone
endometriosis,
a
decrease
noted
comparison
other
groups.
gonadotropins
prolactin
groups
comparable.
In
groups,
days
cycle
lower
than
group.
concentration
patients’
peripheral
compared
group,
minimum
value
16.3
4.1
ng/ml
found
those
disease
no
differences
between
onset
its
duration,
total
daily
insulin
dose,
dose
per
kilogram
weight.
higher
distributing
grades
prevalence,
it
that
III
IV
more
common
without
incidence
deep
infiltrating
only,
as
number
reoperations.
Conclusions:
asymptomatic
preclinical
period
may
lead
untimely
erroneous
delayed
treatment
disease.
puberty
suffering
from
risk
vascular
complications
increases
ovarian
reserve
decreases,
which
requires
goals
early
possible.
choosing
therapy
for
mellitus,
presence
should
be
taken
into
account.
Diabetes
mellitus
(DM)
poses
a
significant
challenge
to
global
health,
with
its
prevalence
projected
rise
dramatically
by
2045.
This
narrative
review
explores
the
bidirectional
relationship
between
periodontitis
(PD)
and
type
1
diabetes
(T1DM),
focusing
on
cellular
molecular
mechanisms
derived
interplay
oral
microbiota
host
immune
response.
A
comprehensive
search
of
literature
published
2008
2023
was
conducted
elucidate
association
these
two
diseases.
Preclinical
clinical
evidence
suggests
relationship,
individuals
T1DM
exhibiting
heightened
susceptibility
periodontitis,
vice
versa.
The
includes
recent
findings
from
human
studies,
revealing
variations
in
composition
patients,
including
increases
certain
pathogenic
species
such
as
Porphyromonas
gingivalis,
Prevotella
intermedia,
Aggregatibacter
actinomycetemcomitans,
along
shifts
microbial
diversity
abundance.
Molecular
underlying
this
involve
oxidative
stress
dysregulated
responses,
mediated
inflammatory
cytokines
IL-6,
IL-8,
MMPs.
Furthermore,
disruptions
bone
turnover
markers,
RANKL
OPG,
contribute
periodontal
complications
patients.
While
preventive
measures
manage
patients
may
improve
overall
health
outcomes,
further
research
is
needed
understand
intricate
interactions
microbiota,
response,
disease,
systemic
population.
Journal of Diabetes Science and Technology,
Год журнала:
2024,
Номер
18(4), С. 808 - 818
Опубликована: Май 7, 2024
The
older
population
is
increasing
worldwide
and
up
to
30%
of
adults
have
diabetes.
Older
with
diabetes
are
at
risk
glucose-related
acute
chronic
complications.
Recently,
mostly
in
type
1
(T1D),
continuous
glucose
monitoring
(CGM)
devices
proven
beneficial
improving
time
range
(TIR
glucose,
70-180
mg/dL
or
3.9-10
mmol/L),
glycated
hemoglobin
(HbA1c),
lowering
hypoglycemia
(time
below
[TBR]
<70
<3.9
mmol/L).
international
consensus
group
formulated
CGM
glycemic
targets
relating
based
on
very
limited
data.
Their
recommendations,
expert
opinion,
were
aimed
mitigating
all
adults.
However,
a
heterogeneous
group,
ranging
from
healthy
complex
frail
individuals
chronological,
biological,
functional
aging.
Recent
clinical
trial
real-world
data,
T1D,
demonstrated
that
often
achieve
targets,
including
TIR
recommended
for
non-vulnerable
groups,
but
less
meet
the
TBR
<1%.
Existing
data
also
support
avoidance
may
be
more
strongly
related
minimization
variability
(coefficient
variation
[CV])
rather
than
lower
TIR.
Very
available
goals
adjusted
complexity
their
health
status.
Herein,
we
review
bidirectional
associations
between
status
diabetes;
use
technologies,
impact
control;
discuss
current
guidelines;
propose
new
set
insulin-treated
individualized
living
Journal of obstetrics and women s diseases,
Год журнала:
2025,
Номер
73(6), С. 101 - 115
Опубликована: Янв. 30, 2025
Background:
Type
1
diabetes
mellitus
and
endometriosis
significantly
reduce
the
quality
of
patient’s
life
hinder
implementation
reproductive
plans.
Studying
features
clinical
course
in
patients
with
type
will
help
development
new
effective
safe
therapeutic
strategies
diagnostic
methods.
Aim:
The
aim
this
study
was
to
analyze
diseases,
hormonal
status
blood
vitamin
D
(25-hydroxycalciferol)
levels
combined
endometriosis.
Materials
methods:
This
prospective
included
339
women,
whom
79
were
(mean
age
31.7
±
5.0
years),
51
31.4
3.7
209
30.2
4.9
years).
control
group
consisted
31
healthy
women
age.
immunochemiluminescent
method
used
determine
serum
anti-Müllerian
hormone,
follicle-stimulating
luteinizing
prolactin,
estradiol
(days
2–5
menstrual
cycle),
progesterone
20–23
cycle)
during
three
consecutive
cycles,
level
glycated
hemoglobin
also
studied
mellitus.
diagnosis
all
confirmed
based
on
laparoscopic
surgery
verification
by
histological
examination.
Results:
When
assessing
gonadotropins,
hormone
endometriosis,
a
decrease
noted
comparison
other
groups.
gonadotropins
prolactin
groups
comparable.
In
groups,
days
cycle
lower
than
group.
concentration
patients’
peripheral
compared
group,
minimum
value
16.3
4.1
ng/ml
found
those
disease
no
differences
between
onset
its
duration,
total
daily
insulin
dose,
dose
per
kilogram
weight.
higher
distributing
grades
prevalence,
it
that
III
IV
more
common
without
incidence
deep
infiltrating
only,
as
number
reoperations.
Conclusions:
asymptomatic
preclinical
period
may
lead
untimely
erroneous
delayed
treatment
disease.
puberty
suffering
from
risk
vascular
complications
increases
ovarian
reserve
decreases,
which
requires
goals
early
possible.
choosing
therapy
for
mellitus,
presence
should
be
taken
into
account.
