Expanding applications of GLP-1 therapies: a careful view DOI
Domenico Azzolino, Tiziano Lucchi

International Journal of Obesity, Год журнала: 2025, Номер unknown

Опубликована: Апрель 16, 2025

Язык: Английский

Use of Continuous Glucose Monitoring in Older People with Diabetes DOI
Giuseppe Maltese

Опубликована: Янв. 31, 2025

Язык: Английский

Процитировано

0

Special Issues in Old Age DOI
Alan J. Sinclair,

Ahmed H. Abdelhafiz,

Alex Michael Summerbell

и другие.

Опубликована: Янв. 31, 2025

Язык: Английский

Процитировано

0

Insulin Therapy DOI
Giuseppe Maltese

Опубликована: Янв. 31, 2025

Процитировано

0

Patient and physician factors driving the gaps in use of drugs with cardiovascular and kidney benefits by medicare beneficiaries with type 2 diabetes treated by endocrinologists, nephrologists, and cardiologists: Population-based cohort study DOI Creative Commons
Rozalina G. McCoy, Jonathan L. Vandergrift, Bradley M. Gray

и другие.

Diabetes Research and Clinical Practice, Год журнала: 2025, Номер 221, С. 112039 - 112039

Опубликована: Фев. 7, 2025

Endocrinologists, nephrologists, and cardiologists care for people with type 2 diabetes (T2D) coexisting cardiovascular disease (CVD), heart failure (HF), and/or chronic kidney (CKD). Glucagon-like peptide-1 receptor agonists (GLP-1RA) sodium-glucose cotransporter inhibitors (SGLT2i) should be preferentially used, but are underutilized. We examine patient physician factors associated GLP-1RA/SGLT2i use by patients treated these subspecialists. Retrospective cohort study using linked 2022 Medicare American Board of Internal Medicine data adults >65 years T2D CVD, HF, CKD their treating endocrinologists, cardiologists. identified 246,106/254,425/435,773 5,661/8,233/10,874 endocrinologists/nephrologists/cardiologists in 2022. Overall, 73.2 % endocrinologist-treated filled medications prescribed endocrinologists; 41.9 GLP-1RA/SGLT2i. Patients nephrologists were rarely subspecialists (9.8 6.1 %, respectively); however, conditional on filling any medication, they more likely to fill a (59.5 48.2 respectively). Older endocrinologists older cardiologists, less Many, particularly older, be, not, GLP-1RA/SGTL2i. Physician training may improve statistics.

Язык: Английский

Процитировано

0

Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies DOI
Medha Munshi, Anna R. Kahkoska, Joshua J. Neumiller

и другие.

The Lancet Diabetes & Endocrinology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

The Effectiveness of a Primary Care Diabetes Education and Self‐Management Program in Ireland: A 6‐Month Follow‐Up Study DOI Creative Commons
Clodagh Scannell, Terence W O’Neill, Anne Griffin

и другие.

Endocrinology Diabetes & Metabolism, Год журнала: 2025, Номер 8(2)

Опубликована: Фев. 19, 2025

ABSTRACT Aims Self‐management education is recognised as an essential element of comprehensive diabetes care. This study aims to assess the impact DESMOND (Diabetes Education and Self‐Management for Ongoing Newly Diagnosed) structured self‐management programme administered by a registered dietitian in primary‐care setting on key clinical indicators (HbA1c, weight BMI) participants who returned locally developed 6‐month follow‐up session. Methods A retrospective analysis was conducted attended 6‐h during 2018 Midwest Ireland. Paired sample t‐tests McNemar chi‐square tests were used any differences between baseline 6 months post‐intervention. Results There 66 participants, mean age 63 years. At follow‐up, HbA1c reduced 6.45 mmol/mol (standard deviation (SD): 15.02 mmol/mol, p = 0.006). The number below 53 cut‐off increased from 52% at 71% ( < 0.001). reduction 1.4 kg (SD: 4.4 kg, 0.21) found follow‐up. Those overweight BMI category decreased 30.2% 26.4%, clinically significant result. Conclusion Better glycaemic control improvements seen among program supports emerging evidence effectiveness Further research required determine optimal contact time frequency sessions order sustain observed improvement outcomes.

Язык: Английский

Процитировано

0

Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)—Special Interest Group in Diabetes DOI Creative Commons
Virginia Boccardi,

Gülistan Bahat,

Cafer Balcı

и другие.

European Geriatric Medicine, Год журнала: 2025, Номер unknown

Опубликована: Фев. 27, 2025

This position paper aims to address the challenges of managing type 2 diabetes mellitus (T2DM) in frail older adults, a diverse and growing demographic with significant variability health status. The primary research questions are: How can frailty assessment be effectively integrated into care? What strategies optimize glycaemic control outcomes for adults? innovative tools technologies, including artificial intelligence (AI), improve management this population? uses 5 I's framework (Identification, Innovation, Individualization, Integration, Intelligence) integrate care, proposing such as tools, novel therapies, digital AI systems. It also examines metabolic heterogeneity, highlighting anorexic-malnourished sarcopenic-obese phenotypes. proposed highlights importance tailoring targets levels, prioritizing quality life, minimizing treatment burden. Strategies leveraging are emphasized their potential enhance personalized care. distinct needs two phenotypes outlined, specific recommendations each group. calls holistic, patient-centered approach care ensuring equity access innovations life. need fill evidence gaps, refine healthcare integration better vulnerable

Язык: Английский

Процитировано

0

Exploring Care Challenges and Needs of People With Diabetes Comorbid Cognitive Impairment From the Triangular Perspectives DOI
W. H. Shen, Jong‐Ni Lin, Sherry Kit Wa Chan

и другие.

Nursing and Health Sciences, Год журнала: 2025, Номер 27(1)

Опубликована: Март 1, 2025

The study explored the challenges and needs in diabetes care for people with comorbid cognitive impairment from triangular perspectives of educators, patients, family caregivers. employed a phenomenological research design qualitative data collection, involving semi-structured interviews 8 7 6 were gathered health education center hospital Taiwan. Thematic analysis was utilized to analyze data. Three categories eight themes emerged. Challenges included "care compliance", "limited involvement", "caregiver distress". Needs identified as "training educators on impairments", education", "standard procedures". Clinical realities showed "inconsistent awareness" "lack consensus resource referrals among professionals". Diabetes faces including poor compliance limited cooperation, requiring better comorbidity training caregivers, standardized procedures healthcare professionals. Findings can guide future programs serve

Язык: Английский

Процитировано

0

The impact of ideglira in treatment simplification in older adults with type 2 diabetes mellitus already on insulin therapy: The stop study DOI Creative Commons
Michelantonio De Fano, Alessio Mazzieri, Carmine G. Fanelli

и другие.

Diabetes Research and Clinical Practice, Год журнала: 2025, Номер unknown, С. 112119 - 112119

Опубликована: Март 1, 2025

The STOP study is a proof-of-concept, aimed at evaluating the effectiveness and safety of IdegLira in deintensifying diabetes therapy elderly insulin-treated persons with T2DM. was real world, single center retrospective observation. 96 were enrolled (46F, age 77 ± 7 yrs, HbA1C 7.5 1.0, duration 21 10 yrs; 75 % basal/bolus insulin therapy). After 6 months (T6), fasting plasma glucose significantly decreased as compared to T0, did HbA1C. switch associated lower rates level 1 (L1) hypoglycemia T3 (IR 0.24, 95 CI 0.11-0.58, p < 0.001) T6 0.08, 0.02-0.34, T0. Level 2 (L2) 0.04, 0.01-0.32, proportion (incidence) L1 from 33.7 T0 17.4 (p = 0.004) 5.8 0.001). Incidence L2 22.1 1.16 No patients had T6. Rapid acting interrupted 85 patients. represents viable option an population.

Язык: Английский

Процитировано

0

Didang Decoction Improves Gut Microbiota and Cognitive Function in TDACD Rats: Combined Proteomics and 16S rRNA Sequencing DOI
Zihan Li,

Caiyi Long,

Jiajing Tao

и другие.

Phytomedicine, Год журнала: 2025, Номер unknown, С. 156758 - 156758

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0