Pathogenomic Insights into Xanthomonas oryzae pv. oryzae’s Resistome, Virulome, and Diversity for Improved Rice Blight Management DOI Creative Commons
Peter Adeolu Adedibu, Oksana Son,

Liudmila Tekutyeva

и другие.

Life, Год журнала: 2024, Номер 14(12), С. 1690 - 1690

Опубликована: Дек. 20, 2024

Oryza sativa (rice) is a major staple food targeted for increased production to achieve security. However, threatened by several biotic and abiotic factors, of which bacterial blight disease caused Xanthomonas oryzae pathovar severe. Developing effective control strategies requires an up-to-date understanding its pathogenomics. This study analyzes the genomes 30 X. strains collected from rice-producing regions across five continents identify genetic elements critical pathogenicity adaptability intraspecific diversity assessment using advanced genomics bioinformatics tools. Resistome analysis revealed 28 distinct types antibiotic resistance genes (ARGs), both innate acquired, indicating growing threat multidrug-resistant strains. Sixteen virulent genes, including type III VI secretion systems, motility effector proteins, were identified. A unique ‘MexCD-OprJ’ multidrug efflux system was detected in Tanzanian strains, conferring multiple classes. To curb further ARG emergence, there need regulate use antibiotics adopt resistant rice varieties. Transposable also discovered contribute pathogenicity, facilitating horizontal transfer virulence genes. Pangenome variation among population, with 112 CDS having diverse functional roles. Strains registered Philippines had most Phylogenetic confirmed divergent evolution oryzae. study’s results will aid identifying more management biocontrol alternatives sustainable production.

Язык: Английский

Pathogenomic Insights into Xanthomonas oryzae pv. oryzae’s Resistome, Virulome, and Diversity for Improved Rice Blight Management DOI Creative Commons
Peter Adeolu Adedibu, Oksana Son,

Liudmila Tekutyeva

и другие.

Life, Год журнала: 2024, Номер 14(12), С. 1690 - 1690

Опубликована: Дек. 20, 2024

Oryza sativa (rice) is a major staple food targeted for increased production to achieve security. However, threatened by several biotic and abiotic factors, of which bacterial blight disease caused Xanthomonas oryzae pathovar severe. Developing effective control strategies requires an up-to-date understanding its pathogenomics. This study analyzes the genomes 30 X. strains collected from rice-producing regions across five continents identify genetic elements critical pathogenicity adaptability intraspecific diversity assessment using advanced genomics bioinformatics tools. Resistome analysis revealed 28 distinct types antibiotic resistance genes (ARGs), both innate acquired, indicating growing threat multidrug-resistant strains. Sixteen virulent genes, including type III VI secretion systems, motility effector proteins, were identified. A unique ‘MexCD-OprJ’ multidrug efflux system was detected in Tanzanian strains, conferring multiple classes. To curb further ARG emergence, there need regulate use antibiotics adopt resistant rice varieties. Transposable also discovered contribute pathogenicity, facilitating horizontal transfer virulence genes. Pangenome variation among population, with 112 CDS having diverse functional roles. Strains registered Philippines had most Phylogenetic confirmed divergent evolution oryzae. study’s results will aid identifying more management biocontrol alternatives sustainable production.

Язык: Английский

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