Development of an RBD-Fc fusion vaccine for COVID-19
Vaccine X,
Год журнала:
2024,
Номер
16, С. 100444 - 100444
Опубликована: Янв. 1, 2024
Although
the
global
pandemic
of
SARS-CoV-2
has
passed,
there
are
still
regional
outbreaks
that
continue
to
jeopardize
human
health.
Hence,
is
a
great
deal
interest
in
developing
an
efficient
vaccine
can
quickly
and
effectively
prevent
reemerging
SARS-CoV-2.
Delta
variant
was
once
dominant
strain
world
2021,
we
first
constructed
recombinant
RBDdelta-Fc
fusion
by
coupling
RBD
with
Fc
fragment.
This
strategy
increases
immunogenicity
vaccine,
long-lasting
high
level
IgG
antibodies
neutralizing
induced
vaccine.
as
well
RBD-Fc
prepared
our
previously
study,
could
trigger
durable
immune
effect
heterologous
boosting
immunity,
quicker
humoral
response
than
homologous
immunization
inactivated
vaccines.
In
conclusion,
significant
role
enhancing
protein
vaccines,
thus
promising
development
safe
for
against
Язык: Английский
Mental health and psychological resilience amid the spread of the Omicron variant: a comparison between China and Korea
Frontiers in Public Health,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 7, 2025
Besides
physical
health
risks,
large
public
events
also
exert
negative
impacts
on
people's
mental
health.
We
aimed
to
explore
the
prevalence
and
correlates
of
distress
its
association
with
psychological
resilience
among
countries
amid
Omicron
wave.
conducted
cross-sectional
surveys
simultaneously
in
China
South
Korea
from
March
15
30,
2023.
Brief
Resilience
Scale
(BRS),
Generalized
Anxiety
Disorder
7-item
(GAD-7)
scale,
Patient
Health
Questionnaire-9
(PHQ-9)
scale
were
used
measured
distress.
Self-reported
rates
anxiety
depressive
symptoms
3,000
Chinese
participants
24.5%
30.5%,
while
above-mentioned
17.2%and
34.4%
1,000
Korean
participants.
had
a
marginally
higher
BRS
score.
Psychological
was
inversely
associated
symptoms.
Similar
results
can
be
observed
Korea.
Results
remained
robust
all
models.
populations
reported
high
variations
different
characteristics,
indicating
practical
implications
for
developing
tailored
policies
services
context
events.
Язык: Английский
Role of research Laboratories in pandemic and epidemic response in the Eastern Mediterranean Region: Experiences from COVID‐19, avian influenza, and MERS‐CoV
Influenza and Other Respiratory Viruses,
Год журнала:
2024,
Номер
18(2)
Опубликована: Фев. 1, 2024
Abstract
We
share
the
experience
of
research
laboratories
in
Eastern
Mediterranean
Region
(EMR)
that
contributed
to
preparedness
and
response
highly
pathogenic
avian
influenza
(HPAI),
Middle‐East
respiratory
syndrome
coronavirus
(MERS‐CoV),
disease
(COVID‐19).
Research
groups
region
were
pivotal
identifying,
characterizing
pathogens
describing
their
evolution,
distribution,
transmission
routes,
immunological
profile
exposed
populations.
They
demonstrated
capacity
develop
test
antivirals
potential
vaccines.
The
EMR
is
a
model
how
national
systems
can
work
with
researchers
improve
regional
future
epidemics
pandemics.
Язык: Английский
Stability and Performance of Conventional and Sharia Banking in Indonesia Before and After the Covid-19 Pandemic
Taufik Eko Nugroho,
Nur Dhani Hendranastiti
Journal of Finance and Islamic Banking,
Год журнала:
2024,
Номер
7(1)
Опубликована: Июль 29, 2024
This
study
examines
the
impact
of
COVID-19
outbreak
on
performance
and
stability
Indonesia's
dual
banking
system.
Our
sample
includes
top
20
banks
by
assets,
both
conventional
sharia,
from
2018
Q1
to
2023
Q3.
Data
for
is
obtained
Bloomberg,
while
data
Islamic
sourced
each
bank's
official
website.
We
use
ROA,
ROE,
NIM
as
variables
Z-Score
NPL
variables.
External
factors
such
GDP,
Inflation,
BI
Rate,
Exchange
Rate
serve
independent
variables,
bank-specific
act
controls.
Panel
regression
used
determine
causal
relationships
between
these
stability.
also
compare
bank
before
after
using
Mann-Whitney
Test.
Findings
indicate
that
pandemic
significantly
affected
banks'
Z-Score,
NPL,
NIM,
only
was
in
sharia
banks.
The
results
highlight
significant
exchange
rate,
inflation
had
no
effect.
type
influences
but
not
Язык: Английский