Brain fog in central disorders of hypersomnolence: a review
Journal of Clinical Sleep Medicine,
Год журнала:
2024,
Номер
20(4), С. 643 - 651
Опубликована: Янв. 16, 2024
Brain
fog
is
an
undefined
term
describing
a
cluster
of
symptoms
related
to
fatigue
and
impaired
memory,
attention,
concentration.
or
brain
fog-like
have
been
reported
in
central
disorders
hypersomnolence
range
seemingly
unrelated
disorders,
including
coronavirus
disease
2019,
major
depressive
disorder,
multiple
sclerosis,
lupus,
celiac
disease.
This
narrative
review
summarizes
current
evidence
proposes
consensus
definition
for
fog.
prevalent
narcolepsy
idiopathic
hypersomnia,
with
more
than
three-quarters
patients
either
disorder
reporting
this
symptom
registry
study;
it
has
also
as
particularly
difficult
treat
hypersomnia.
Studies
directly
evaluating
are
rare;
tools
typically
patient
reports,
few
objective
measures
validated
any
disorder.
Evaluating
further
complicated
by
confounding
symptoms,
such
excessive
daytime
sleepiness,
which
hallmark
disorders.
No
treatments
specifically
address
The
paucity
literature,
assessment
tools,
medications
highlights
the
need
research
leading
better
disambiguation
treatment.
Until
clear
established,
we
propose
hypersomnia
be
defined
cognitive
dysfunction
that
may
not
linked
underlying
neuronal
dysfunction,
reduces
concentration
impairs
information
processing,
complaint
lack
clarity
mental
thinking
awareness.
Язык: Английский
Defining brain fog across medical conditions
Trends in Neurosciences,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 1, 2025
'Brain
fog'
is
commonly
reported
in
more
than
a
dozen
chronic
diseases,
but
what
it?
We
review
research
across
conditions
which
has
characterised
brain
fog
and
evaluate
its
definitions
objective
correlates.
Brain
been
used
to
refer
variable
set
of
overlapping
symptoms
implicating
cognition,
fatigue,
affect.
It
defined
as
distinct
symptom,
syndrome,
or
nonspecific
term.
consider
the
evidence
that
transdiagnostic
entity
with
common
phenomenology
profile
cognitive
deficits.
discuss
where
these
commonalities
arise
argue
linguistic
ambiguity,
shared
impairments,
noncognitive
factors
are
likely
neurobiology.
suggest
how
future
might
apply
existing
tools
disambiguate
phenomena
conflates.
Язык: Английский
Brain Fog and Cognitive Dysfunction in Posttraumatic Stress Disorder: An Evidence-Based Review
Psychology Research and Behavior Management,
Год журнала:
2025,
Номер
Volume 18, С. 589 - 606
Опубликована: Март 1, 2025
Abstract:
The
term
"brain
fog"
has
long
been
used
both
colloquially
and
in
research
literature
reference
to
various
neurocognitive
phenomenon
that
detract
from
cognitive
efficiency.
We
define
as
the
subjective
experience
of
difficulties,
keeping
with
most
common
colloquial
use
term.
While
a
recent
increase
this
largely
context
post-coronavirus-19
condition
known
COVID,
also
discussed
relation
several
other
conditions
including
mental
health
such
post-traumatic
stress
disorder
(PTSD).
PTSD
is
associated
complaints
relative
deficits
on
testing,
but
phenomenology
mechanisms
contributing
population
are
poorly
understood.
psychopathology
across
cognitive,
affective
physiological
symptom
domains
have
tied
fog".
Furthermore,
dissociative
symptoms
contribute
Comorbid
physical
may
risk
experiencing
among
individuals
PTSD.
Considerations
for
assessment
part
psychodiagnostic
discussed.
standard
psychological
intervention
reduction
deficits,
interventions
be
valuable
when
persists
following
remission
or
interferes
treatment.
Limitations
current
include
lack
consistent
definition
operationalization
literature,
well
limited
tools
measurement.
Future
should
address
these
limitations,
further
evaluate
remediation
an
Keywords:
cognition,
complaints,
fatigue,
trauma
Язык: Английский
Clinical Considerations in the Treatment of Idiopathic Hypersomnia
Sleep Medicine,
Год журнала:
2024,
Номер
119, С. 488 - 498
Опубликована: Май 7, 2024
Idiopathic
hypersomnia
typically
is
a
chronic
and
potentially
debilitating
neurologic
sleep
disorder,
characterized
by
excessive
daytime
sleepiness.
In
addition
to
sleepiness,
idiopathic
symptoms
can
include
severe
inertia;
long,
unrefreshing
naps;
long
time;
cognitive
dysfunction.
Patients
with
may
experience
significant
impact
on
their
quality
of
life,
work
or
school
performance,
earnings,
employment,
overall
health.
Given
the
complex
range
associated
array
treatments
available,
there
need
provide
guidance
treatment
clinically
relevant
recommendations
that
enhance
effective
disease
management.
Identifying
appropriate
options
for
requires
timely
accurate
diagnosis,
consideration
individual
patient
factors,
frequent
reassessment
symptom
severity.
2021,
low-sodium
oxybate
was
first
receive
approval
US
Food
Drug
Administration
in
adults.
However,
many
off-label
continue
be
used.
Adjunct
nonpharmacologic
therapies,
including
good
hygiene,
education
counseling,
use
support
groups,
should
recognized
recommended
when
appropriate.
This
narrative
review
describes
optimal
strategies
take
into
account
patient-specific
as
well
unique
characteristics
each
medication
evolution
patient's
response
treatment.
Perspectives
measurement
management,
potential
future
are
also
offered.
Язык: Английский