DNA Nanotechnology in Oligonucleotide Drug Delivery Systems: Prospects for Bio-nanorobots in Cancer Treatment DOI Creative Commons
HANIYEH ABDOLLAHZADEH, Tonya L. Peeples,

Mohammad Shahcheraghi

и другие.

Опубликована: Авг. 16, 2024

DNA-based nanomaterials have shown great potential in numerous applications, thanks to their unique properties including DNA's various molecular interactions, programmability, and versatility with biological modules. Meanwhile, the DNA origami platforms promise creation of drug carriers. This technique has paved way for production nanomachines outstanding performance. Moreover, DNA’s encoding capability its massive parallelism help us manipulate it computation. The nanotechnology method holds potential, particularly oligonucleotide therapeutics that enable precision medicine cancers. Here, we explore this context, focusing on our efforts streamline process. We then delve into studies demonstrating application delivering drugs tumor targeting. Following this, examine dynamic nanodevices can be activated through binding, environmental stimuli, external field manipulation. Subsequently, investigate role computation logic gates, circuits, data storage, machine learning. Finally, envision future development 'bio-nanorobots' based DNA, enabled by advancements propose combining could facilitate realization vision, distinguishing from conventional delivery systems.

Язык: Английский

Molecular dynamics study on enhancing the structural and mechanical properties of biomimetic DNA and RNA nanotubes using polyamines DOI
Ehsan Torkan, Mehdi Salmani-Tehrani

Chemical Physics Letters, Год журнала: 2025, Номер unknown, С. 141968 - 141968

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

DNA Nanotechnology in Oligonucleotide Drug Delivery Systems: Prospects for Bio-nanorobots in Cancer Treatment DOI Creative Commons
HANIYEH ABDOLLAHZADEH, Tonya L. Peeples,

Mohammad Shahcheraghi

и другие.

Опубликована: Авг. 16, 2024

DNA-based nanomaterials have shown great potential in numerous applications, thanks to their unique properties including DNA's various molecular interactions, programmability, and versatility with biological modules. Meanwhile, the DNA origami platforms promise creation of drug carriers. This technique has paved way for production nanomachines outstanding performance. Moreover, DNA’s encoding capability its massive parallelism help us manipulate it computation. The nanotechnology method holds potential, particularly oligonucleotide therapeutics that enable precision medicine cancers. Here, we explore this context, focusing on our efforts streamline process. We then delve into studies demonstrating application delivering drugs tumor targeting. Following this, examine dynamic nanodevices can be activated through binding, environmental stimuli, external field manipulation. Subsequently, investigate role computation logic gates, circuits, data storage, machine learning. Finally, envision future development 'bio-nanorobots' based DNA, enabled by advancements propose combining could facilitate realization vision, distinguishing from conventional delivery systems.

Язык: Английский

Процитировано

2