Does hypertension affect the course of coronavirus infection

Spravočnik vrača obŝej praktiki (Journal of Family Medicine), Год журнала: 2025, Номер 2, С. 17 - 22

Опубликована: Фев. 15, 2025

Through dynamic follow-up over the past year and a half, it has been found that patients with COVID-19 on background of hypertension suffer more severely from this disease often require medical care in intensive unit. In addition, laboratory studies showed significant increase levels D-dimer, LDH, C-reactive protein such patients. Patients coronavirus infection accompanied by had severe course pneumonia respiratory failure, development an excessive inflammatory reaction form cytokine storm was observed frequently. At same time, doctors believe is not directly related to high blood pressure, but fact suffering arterial have concomitant diseases as obesity diabetes, most cases belong older age group. Despite itself factor contributing complicated infection, pathology careful monitoring personnel cautious selection drug therapy.

Язык: Английский

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Clinical guidelines of the Russian Medical Society on arterial Hypertension (RSH) and the Eurasian association of Cardiologists (EaC) for the diagnosis and treatment of arterial hypertension (2024)

Systemic Hypertension, Год журнала: 2024, Номер 21(4), С. 5 - 110

Опубликована: Дек. 25, 2024

The сlinical guidelines present the main approaches to management of patients with arterial hypertension (aH) using principles evidence-based medicine. include sections containing expanded and updated information on aspects diagnosis, treatment, prevention methods follow-up hypertension, taking into account phenotypes disease various clinical situations, as well secondary forms origins.

Язык: Английский

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ARTERIAL HYPERTENSION AND COVID-19: POSSIBLE RELATIONSHIP

Современные проблемы науки и образования (Modern Problems of Science and Education), Год журнала: 2023, Номер №2 2023, С. 1 - 1

Опубликована: Янв. 1, 2023

АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ И COVID-19: ВОЗМОЖНЫЕ ВЗАИМООТНОШЕНИЯ Рябова А.Ю

Язык: Русский

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Clinical features of arterial hypertension in patients with mild and moderate COVID-19

Saratov Journal of Medical Scientific Research, Год журнала: 2023, Номер 19(1), С. 46 - 50

Опубликована: Март 31, 2023

Objective: to clarify the clinical and diagnostic features of arterial hypertension in patients with mild moderate forms COVID-19, taking into account elapsed time. Material methods. We examined 116 aged 44-60 years who were admitted hospital uncontrolled stage 2 hypertension, 96 them had COVID-19. The divided two groups: first group up 12 weeks after suffering COVID-19 second weeks. examination included echocardiography ambulatory blood pressure (BP) monitoring. Results. In post-COVID-19 patients, ratio daytime nighttime systolic BP was statistically significantly lower than disease-free (p <0,001, p1 =0,015). There a decrease daily index 1 (11.6±0.8% 12.2±1.2%, respectively, p=0,001). Among non-dippers detected, more often (9 people (17.6%) versus (4.4%) (x2=4.18, p=0.042). Conclusion. Arterial underwent characterized by an insufficient at night, presence positive dynamics from onset infectious process.

Язык: Английский

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Features of the course of COVID-19 in patients with comorbid pathology

Meditsinskiy sovet = Medical Council, Год журнала: 2022, Номер 6, С. 44 - 49

Опубликована: Апрель 21, 2022

Comorbidity is an important problem of modern medicine, the study which a priority for public health. According to literature, prevalence comorbidity reaches third population in some countries, while there tendency increase number such patients all age groups. In context COVID-19 pandemic, presence significant risk factor affecting course and prognosis new coronavirus infection; at same time, it comorbid who belong most vulnerable group. The review presents data indicating impact pathologies on complications mortality; common combinations diseases with infection were analyzed. There groups, dictates need develop integrated interdisciplinary approach patients. vast majority clinical guidelines treatment comorbidities are mainly focused individual diseases, limits use these algorithms Due high contracting viral infection, as well frequent development mortality patients, preventive measures should be simultaneously two tasks: aimed preventing compensating pathology. case SARS-CoV-2 careful monitoring often hospital setting, necessary order prevent adverse outcomes.

Язык: Английский

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Epidemiological Observational Study on the Assessment of the Comorbidity and the Efficacy of the Treatment of Hypertensive Patients with Single Pill Combination of Lysinopril, Amlodipine and Rosuvastatin "PHENOTYPE-AG"

Rational Pharmacotherapy in Cardiology, Год журнала: 2021, Номер 17(4), С. 528 - 536

Опубликована: Сен. 3, 2021

Aim. To study the prevalence of comorbidity affecting choice antihypertensive treatment, as well efficacy and safety application a single pill combination lysinopril, amlodipine rosuvastatin (SPC LAR) in hypertensive patients. Material methods. Observational epidemiological with participation 626 doctors 13037 patients high cardiovascular risk dyslipidemia treated SPC LAR were held 24 cities Russia from November 2020 to March 2021. Prevalence types comorbidity, changes blood pressure (BP), total cholesterol (TC) glucose levels adverse events studied during observation. Patients had 3 visits – initially, after 4 12 weeks. The obtained data was recorded by through web portal. Results. Concominant diseases found all (in 38.7% cases 2 5 diseases). most commonly coronary artery disease (43.1%), metabolic syndrome (36.6%), diabetes (25.2%), chronic heart failure (24.9%), cerebrovascular (12.3%) obstructive pulmonary (0.5%). minimal doses components 41.1% patients) or reinforced hypocholesterolemic effects, based on experience patient prescribed starting treatment doctors. Reducing level systolic diastolic BP, Tc, respectively, 20.9%, 16.9% 29.7% study. Target BP achieved 97.6% patients, 99.6%, target TC ≤5 mmol/l, ≤4 mmol/l ≤3 achieved, 94.5%, 68.6% 23.5% No significant dynamics glycemia not found. tolerated Side effects 0.53% (more often there dry cough, feet edema headache). Commitment 92.7%. Conclusion. modern hypertension phenotype has atherosclerosis-associated diseases, which justifies need combine hypolipidemic therapy. Triple LAR, effectively controlled improved violation lipid metabolism this observational low frequency side good tolerance accompanied adherence treatment.

Язык: Английский

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Depression as a potential factor for the ineffectiveness of hypertension control in post-COVID-19 patients

South Russian Journal of Therapeutic Practice, Год журнала: 2021, Номер 2(3), С. 72 - 77

Опубликована: Окт. 3, 2021

Objective : improving the effectiveness of hypertension control in patients after COVID-19 with manifestations depression. Materials and methods: study included 48 who had suffered a coronavirus infection. The criterion for inclusion was effective blood pressure when using two-component antihypertensive therapy before development disease its absence same at time study. To identify symptoms depression, conducted Beck Depression questionnaire. Group A consisted arterial depression group B-patients without In both groups, combination renin-angiotensin-aldosterone system blocker, diuretic calcium channel blocker were used. observation carried out 4 weeks, dynamics daily parameters, evaluated. Results presence detected 39.5% patients. At study, office exceeded target level all patients, there an insufficient decrease systolic diastolic during day night, increase most indicators variability. use three-component made it possible to achieve 93.1% only 21.0% reached level. analysis showed All statistically significantly higher than B. Conclusion have infection, is necessary as factor ineffective adherence recommended therapy.

Язык: Английский

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Clinical and laboratory characteristics of COVID-19 in hospitalized hypertensive patients

Arterial’naya Gipertenziya (Arterial Hypertension), Год журнала: 2023, Номер 29(2), С. 150 - 163

Опубликована: Май 15, 2023

Objective . To identify clinical and laboratory differences of COVID-19 in patients with hypertension (HTN), as well to factors associated its severe course these patients. Design methods A retrospective analysis case histories 940 was performed. Statistical carried out by the method contingency tables using Pearson's Chi-square test Bonferroni correction, multiple logistic regression ROC-analysis were also applied. Results The group HTN showed a number significant compared without history. study characterized higher rates females, people over 65, COVID-19. They more likely have diabetes mellitus, coronary heart disease, chronic kidney disease. On admission, patients, leukocytosis elevated blood glucose levels common, pneumonia, shortness breath low saturation (p < 0,05). Multivariate that presence disease (odds ratio (OR) = 3,492, 95 % confidential interval (CI): 2,016-6,048), (OR 1,376, CI: 1,540-7,703), thrombocytopenia 1,779, 1,031-3,071) SpO 2 3,265, 1,996-5,341) hypertensive combination identified increases power their association (AUC 0,766). Conclusions 1. Some indicators hospitalized are different no 2. Factors individuals do not differ from those general population 3. Severe strongly SpO2 concomitant

Язык: Английский

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Features of the course and adverse events risk of coronavirus infection COVID-19 in hematological diseases (data from the CHRONOS19 register for the Primorsky Territory, intermediate stage)

Terapevticheskii arkhiv, Год журнала: 2023, Номер 95(7), С. 537 - 542

Опубликована: Сен. 29, 2023

To assess the characteristics of course coronavirus infection COVID-19 and to determine risk factors for adverse events in patients regional hematological center. As part an observational prospective cohort study, data from 144 medical records Primorsky Krai with diseases were analyzed. The developed standardized questionnaire CHRONOS19 study used. primary endpoint (adverse outcome) was a composite point that included mortality any cause during observation period, development acute respiratory distress syndrome, hospitalization intensive care unit, need mechanical ventilation. A features showed increase number neoplastic blood diseases, especially chronic lymphoproliferative myeloid leukemia. Significant predictors unfavorable include refractory/recurrent variant tumor, glucocorticoid therapy as protocol treatment underlying disease, stage 3-4 lung damage according computerised tomography scans at onset COVID-19, presence diabetes mellitus. Predictors have been identified. Hematological context pandemic require coordinated interdisciplinary approach involving hematologists therapists, careful monitoring clinical laboratory parameters reduce events.

Язык: Английский

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Does hypertension affect the course of the coronavirus infection?

Spravočnik vrača obŝej praktiki (Journal of Family Medicine), Год журнала: 2022, Номер 2, С. 28 - 33

Опубликована: Янв. 31, 2022

Through dynamic monitoring over the past year and a half, it has been established that patients with COVID-19 against background of hypertension are more severely affected by this disease often need medical care in intensive unit. In addition, laboratory studies showed significant increase level D-dimer, LDH C-reactive protein such patients. coronavirus infection occurring hypertension, there was severe course pneumonia pronounced respiratory failure, development an excessive inflammatory reaction form «cytokine storm» observed frequently. At same time, doctors believe is not directly related to high blood pressure, but fact people suffering from arterial have concomitant diseases — obesity diabetes, most cases belong older age group. Despite itself factor contributing complicated infection, pathology careful personnel selection drug therapy.

Язык: Английский

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