The Use of MRI and TMS in Treatment-Resistant Depression: Advances in Pediatric Applications

Brain Sciences, Год журнала: 2025, Номер 15(2), С. 194 - 194

Опубликована: Фев. 14, 2025

Treatment-resistant depression (TRD) is a substantial burden for psychiatric care, affecting approximately one-third of patients with major depressive disorder (MDD). Adolescent populations are particularly challenging demographic to treat as early intervention crucial prevent treatment resistance, but options limited. Transcranial magnetic stimulation (TMS) has emerged promising non-invasive option TRD in adults well adolescents, offering hope who have not responded conventional therapies. This review examines the convergence functional resonance imaging (fMRI) tool examine how TMS modulates connectivity adolescents MDD. Such analyses led advances our understanding pathophysiology MDD, TRD, and mechanisms TMS. We this evidence, evaluate methodological approaches, identify critical gaps existing literature, highlighting neuroimaging-guided protocols offer therapeutic avenue adolescent cases where treatments proven ineffective.

Язык: Английский

Beyond case-control study in neuroimaging for psychiatric disorders: Harmonizing and utilizing the brain images from multiple sites

Neuroscience & Biobehavioral Reviews, Год журнала: 2025, Номер 171, С. 106063 - 106063

Опубликована: Фев. 26, 2025

Язык: Английский

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Investigative Radiology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 7, 2025