Functional Foods in Health and Disease,
Год журнала:
2024,
Номер
14(7), С. 503 - 516
Опубликована: Июль 18, 2024
Background:
Kurozu
is
a
traditional
Japanese
rice
vinegar
characterized
by
its
brown
color
and
that
has
been
shown
to
improve
hypertension,
hypercholesterolemia,
carbohydrate
metabolism.
also
suggested
confer
health
benefits
altering
gene
expression;
however,
the
molecular
basis
not
yet
understood.
Objective:
We
previously
reported
intake
of
increased
expression
hepatic
Sirt1
microRNA
(miR).
These
changes
in
may
be
attributed
histone
modifications.
Therefore,
current
research
explored
effects
supplementation
with
concentrated
(CK)
on
modifications
liver.
Methods:
Over
period
50
weeks,
mice
received
high-fat
diet
(HFD),
HFD
CK,
or
standard
(SD).
The
study
focused
impact
CK
related
lipid
metabolism
Results:
A
microarray
analysis
revealed
miR
cluster
located
chromosome
12,
while
this
change
was
suppressed
CK.
chromatin
modification
region
upstream
analyzed
using
Chip
assay.
significantly
levels
dimethylation
H3
lysine
4
(H3K4me2)
monoacetylation
27
(H3K27ac).
H3K4me2
levels,
inhibited
MiR-127-5p
-134-5p,
which
are
present
cluster,
MLXIPL,
transcription
factor
involved
synthesizing
fatty
acids
from
carbohydrates.
Further
experiments
human
colon
cancer
cells
demonstrated
miR-127-5p
-134-5p
knocked
down
MLXIPL.
Conclusion:
results
affects
changing
HFD-induced
increases
levels.
Furthermore,
upregulated
turn
Keywords:
modification,
genomic
imprinting,
diet,
Kurozu,
microRNA,
MLXIPL
Foods,
Год журнала:
2023,
Номер
12(21), С. 4001 - 4001
Опубликована: Ноя. 1, 2023
This
review
delves
into
the
concept
of
nutrition
by
design,
exploring
relationship
between
poultry
production,
utilization
dietary
by-products
to
create
functional
foods,
and
their
impact
on
human
health.
Functional
foods
are
defined
as
products
that
extend
beyond
basic
nutritional
value,
offering
potential
benefits
in
disease
prevention
management.
Various
methods,
including
extraction,
fermentation,
enrichment,
biotechnology,
nanotechnology,
employed
obtain
bioactive
compounds
for
these
foods.
also
examines
innovative
approach
enhancing
livestock
diets
through
animal-based
methods.
Bioactive
found
such
essential
fatty
acids,
antioxidants,
carotenoids,
minerals,
vitamins,
peptides,
highlighted
promoting
well-being
mitigating
chronic
diseases.
Additionally,
explores
functionality
food
components
within
products,
emphasizing
critical
roles
bioaccessibility,
bioactivity,
bioavailability
The
importance
considering
key
aspects
design
enhanced
production
is
thoroughly
reviewed.
safety
establishment
regulations
guidelines
was
It
concluded
integration
principles
empowers
individuals
make
informed
choices
can
prioritize
health
well-being.
By
incorporating
rich
compounds,
consumers
proactively
take
steps
prevent
manage
issues,
ultimately
contributing
a
healthier
society
lifestyle.
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Год журнала:
2023,
Номер
6(7), С. 166 - 166
Опубликована: Июль 31, 2023
The
increasing
demand
for
functional
foods,
stemming
from
the
growing
health
consciousness
among
consumers
and
their
preference
products
that
provide
more
than
just
basic
nutrition,
presents
both
opportunities
challenges
regulatory
agencies,
notably
U.S.
Food
Drug
Administration
(FDA).
Functional
foods
lack
a
specific
category,
leading
to
uncertainties
manufacturers
consumers.
Collaboration
between
FDA
Center
(FFC)
is
proposed
as
solution
enhance
food
regulation.
FFC's
expertise
in
biomedical
sciences
its
17-step
process
defining
can
contribute
valuable
scientific
research
aid
FDA's
evaluation
process.
By
fostering
collaboration,
organizations
ensure
consumer
protection
promote
public
while
meeting
foods.
Keywords:Functional
claims,
regulation,
definition,
demand,
collaboration
Nutrients,
Год журнала:
2023,
Номер
15(16), С. 3583 - 3583
Опубликована: Авг. 15, 2023
Gastroesophageal
reflux
disease
(GERD)
is
a
common
esophageal
disorder
characterized
by
troublesome
symptoms
associated
with
increased
acid
exposure.
The
cornerstones
of
therapy
in
this
regard
include
treatment
acid-suppressive
agents,
lifestyle
modifications,
and
dietary
therapy,
although
the
latter
has
not
been
well
defined.
As
concerns
regarding
long-term
proton
pump
inhibitor
(PPI)
use
continue
to
be
explored,
patients
healthcare
providers
are
becoming
increasingly
interested
role
diet
management.
However,
interventions
lack
evidence
synthesis
effect
functional
foods.
following
review
for
GERD,
emphasizing
food
components’
impact
on
GERD
pathophysiology
Although
sequential
elimination
groups
practice,
literature
supports
broader
intervention,
including
reduced
overall
sugar
intake,
fiber,
changes
eating
practices.
While
primary
concern
companies
provide
safe
products,
caloric,
nutritional,
composition
foods
also
generating
interest
industry
due
consumers’
concerns.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2023,
Номер
64(24), С. 8501 - 8539
Опубликована: Апрель 25, 2023
Foods
are
complex
biosystems
made
up
of
a
wide
variety
compounds.
Some
them,
such
as
nutrients
and
bioactive
compounds
(bioactives),
contribute
to
supporting
body
functions
bring
important
health
benefits;
others,
food
additives,
involved
in
processing
techniques
improving
sensory
attributes
ensuring
safety.
Also,
there
antinutrients
foods
that
affect
bioefficiency
contaminants
increase
the
risk
toxicity.
The
is
evaluated
with
bioavailability
which
represents
amount
or
bioactives
from
consumed
reaching
organs
tissues
where
they
exert
their
biological
activity.
Oral
result
some
physicochemical
processes
liberation,
absorption,
distribution,
metabolism,
elimination
(LADME).
In
this
paper,
general
presentation
factors
influencing
oral
well
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Год журнала:
2024,
Номер
7(2), С. 131 - 140
Опубликована: Фев. 26, 2024
Background:
Among
conventional
grains,
lentils
stand
out
as
a
rich
source
of
nutrients,
boasting
high
levels
protein
and
low
carbohydrates.
They
serve
an
excellent
meat
alternative
are
abundant
in
macronutrients,
micronutrients,
bioactive
phytochemicals.
The
red
lentil
seed
coat
surpasses
other
legumes
phenol
content,
showcasing
remarkable
antioxidant
activity.
Recognized
high-level
functional
crop,
demonstrate
efficacy
mitigating
various
health
issues,
including
hypertension,
cardiovascular
disease,
diabetes,
cancer.
Objective:
This
study
aims
to
analyze
the
biochemical
components,
such
proteins
monosaccharides,
selected
varieties
that
thrive
conditions
Ararat
Valley
hold
economic
value.
objective
is
evaluate
their
potential
foods.
Methods:
was
conducted
at
Scientific
Centre
Vegetables
Industrial
Crops
Darakert,
Armenia,
from
2021
2022,
used
block-randomized
design
with
4
replications.
Lentil
seeds
were
planted
mid-May,
proper
care
optimal
spacing.
Harvested
mid-July,
fruits
underwent
analysis
laboratory.
Investigated
included
those
ICARDA
collection
locally
bred
ones.
Total
protein,
nitrogen,
carbohydrate
content
determined
using
Kjeldahl’s,
Bernstein’s,
Ofner's
iodometric
methods,
respectively.
Results:
investigation
into
properties
revealed
ranging
20.5%
23.9%,
non-protein
between
1.2%
1.6%,
monosaccharides
6.2%
6.7%.
Conclusions:
Economically
valuable
varieties,
both
sourced
(Flip
2007-12L,
Flip
2007-3L,
2007-30L,
EP-54,
Sell
from1767L)
registered
State
Register
Breeding
achievements
Armenia
(Talini-6,
Haykakan88),
exhibit
concentrations
key
proteins,
non-proteins,
monosaccharides.
When
considering
foods
benefits,
these
align
well
contemporary
nutritional
trends
emphasizing
inclusion
health-promoting
ingredients
diets.
Further
research
development
this
area
promise
not
only
expanding
agricultural
culinary
landscape
but
also
contributing
broader
conversation
around
nutrition
world.
Keywords:
lentils,
properties,
non-protein,
