Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(15), С. 8095 - 8095

Опубликована: Июль 25, 2024

Elevated levels of homocysteine (Hcy) and related metabolites are associated with Alzheimer's disease (AD). Severe hyperhomocysteinemia causes neurological deficits worsens behavioral biochemical traits AD. Although Hcy is precluded from entering the Genetic Code by proofreading mechanisms aminoacyl-tRNA synthetases, thus a non-protein amino acid, it can be attached to proteins via an

Язык: Английский

Pathophysiology of Alzheimer’s disease: an insight into the genetic factors, hypotheses, redox imbalance, and antioxidant intervention

Comparative Clinical Pathology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 13, 2024

Язык: Английский