
Frontiers in Neuroscience, Год журнала: 2024, Номер 18
Опубликована: Ноя. 29, 2024
This systematic review and meta-analysis aimed to evaluate the efficacy of combination scalp acupuncture in treating post-stroke cognitive impairment. A comprehensive search was conducted across eight databases: PubMed, Web Science, Cochrane Database, Embase, CBM, CNKI, WanFang, VIP, targeting randomized controlled trials (RCTs) published from inception these databases until October 24, 2024. The inclusion criteria focused on RCTs that compared with conventional treatments as therapeutic interventions for patients suffering impairment (PSCI). effectiveness evaluated using various outcome measures, including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Loewenstein Occupational Therapy (LOTCA), well P300 latency amplitude, which collectively assess function. Two independent reviewers a risk bias (ROB2) assessment, data analysis performed Review Manager (RevMan) version 5.4. included total 28 studies involving 1,995 patients. However, according standards ROB2 tool, most exhibited methodological issues. indicates combined (PSCI) is superior single treatments, evidenced by improvements multiple scales, latency, amplitude. Specifically, overall effective rate reported (RR = 1.28, 95% CI: 1.14-1.45, p < 0.0001; I 2 51%, random effects model). mean differences scales were follows: MoCA (MD 3.55, 2.68-4.41, 93%, model), MMSE 3.78, 2.83-4.73, 94%, LOTCA 9.70, 7.72-11.69, 57%, -21.83, -26.31 -17.35, 55%, amplitude 1.05, 0.76-1.34, 0%, fixed demonstrating low, medium, high levels heterogeneity, respectively. Notably, one study an adverse event related participant withdrawal during study. Combination exhibits single-treatment modalities higher (ROB) suggests quality evidence about assessment results may be compromised. Therefore, there urgent need additional high-quality clinical further validate PSCI, ultimately enhancing level evidence. https://www.crd.york.ac.uk/prospero/, identifier CRD42024519200.
Язык: Английский