Krankenhaushygiene up2date,
Год журнала:
2024,
Номер
19(01), С. 45 - 58
Опубликована: Март 1, 2024
Nachdem
im
Mai
2022
in
Großbritannien
bei
einem
Reiserückkehrer
aus
Nigeria
erstmals
eine
Infektion
mit
Mpox
(vormals
Affenpocken,
Monkeypox)
diagnostiziert
wurde,
wurden
wenig
zeitversetzt
auch
die
ersten
Fälle
Deutschland
gemeldet.
In
den
folgenden
Monaten
wurde
ein
starker
Anstieg
der
Fallzahlen
beobachtet,
insbesondere
Nord-/Südamerika
und
Europa.
gehörte
zu
am
stärksten
betroffenen
Länder
weltweit.
Dieser
Beitrag
gibt
einen
Überblick
über
Erreger,
das
klinische
Bild
sowie
Präventions-
Therapieoptionen.
Dermatology Reports,
Год журнала:
2024,
Номер
unknown
Опубликована: Фев. 6, 2024
Aim.
This
meta-analysis
estimates
the
prevalence
of
sexually
transmitted
diseases
(STIs)
and
HIV
infection
among
male
patients
diagnosed
with
Monkeypox
during
2022
outbreak.
The
study
also
explores
contextual
factors
associated
higher
risk
monkeypox
infection.
Methods.
A
systematic
review
literature
was
initially
conducted
through
PubMed/
Medline,
Scopus,
Google
Scholar
to
retrieve
observational
studies
describing
demographics
medical
characteristics
affected
in
System
for
Unified
Management,
Assessment,
Review
Information
-Joanna
Briggs
Institute
(SUMARI
JBI)
guidelines
used
conduct
this
review.
All
data
relevant
STIs
were
extracted
exported
into
JBI
SUMARI.
To
assess
point
STIs,
we
Freeman-Tukey-type
arcsine
square
root
transformation
stabilize
variances
raw
proportions.
weighted
pooled
by
inverse
variance
using
a
fixed-effects
model.
We
then
random
model
account
sampling
variation
reported
heterogeneity
effect
size
noted
across
fixed-effect
I2
test
statistic
P
values
measure
between
studies.
Values
results
interpreted
as
follows:
low
(25%),
moderate
(50%)
high
(75%).
Results.
Six
from
Spain
UK
met
inclusion
criteria.
These
described
total
541
monkeypox,
214
them
positive
255
had
other
STIs.
Overall
estimated
40%
(95%
CI
=
0.31%,
0.50%;
ᵡ2
15)
43%
25%,
61%;
118),
respectively.
Outcomes
indicated
overall
analyses.
Conclusions.
Approximately
four
ten
outbreak
and/or
Necessary
public
health
measures
should
target
female
who
are
at
prevent
transmission
serious
infections
such
Journal of Tropical Medicine,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Objectives:
After
the
global
impact
of
COVID‐19
pandemic,
concerns
over
virus
transmission
have
risen.
A
state
health
emergency
was
declared
in
2022
due
to
Clade
2
monkeypox
(MPOX)
virus.
In
August
2024,
another
by
World
Health
Organization
(WHO)
because
widespread
1b,
which
caused
a
more
severe
and
lethal
disease.
This
review
synthesizes
current
MPOX
knowledge
assist
policymakers,
clinicians,
researchers
developing
effective
diagnostics,
therapeutic
interventions,
vaccination
strategies,
outbreak
management.
Methods:
systematic
study
searched
for
articles
on
epidemiology,
virology,
clinical
features,
routes,
available
drugs
vaccines,
new
artificial
intelligence
(AI)
applications
diagnosis
drug
discovery.
Results:
is
200–250‐nm,
double‐stranded
DNA
(ds‐DNA)
that
causes
smallpox‐like
skin
lesions.
Tecovirimat
primary
cases,
especially
people
with
suppressed
immune
systems.
Smallpox
vaccines
can
help
prevent
infection
genetic
similarities
between
smallpox
viruses.
AI‐based
models
medical
teams
promptly
diagnosing
lesions,
improving
decision‐making
treatment.
Conclusion:
highlights
importance
using
traditional
public
alongside
modern
AI
manage
outbreaks
effectively.
It
shows
we
need
strong
policies,
focused
ongoing
research
how
control
infectious
diseases.
Medicina,
Год журнала:
2022,
Номер
58(10), С. 1454 - 1454
Опубликована: Окт. 15, 2022
Monkeypox
(MPX)
is
a
zoonotic
infection
caused
by
an
orthopoxvirus
that
endemic
to
Central
and
Western
Africa.
The
MPX
virus
part
of
the
same
family
viruses
as
variola
virus,
which
causes
smallpox.
Since
May
2022,
there
has
been
global
increase
in
incidence
infections
multiple
countries
where
illness
not
usually
prevalent.
A
growing
number
publications
have
emphasized
on
need
for
increased
awareness
among
all
health
professionals
rapid
recognition
diagnosis
this
disease
proper
public
measures.
However,
atypical
presentations
occurrence
uncommon
symptoms
receive
less
than
desired
attention.
More
specifically,
related
nociceptive
are
currently
underexposed.
Nevertheless,
reports
from
current
outbreak
revealed
(severe)
pain
one
major
distress
even
hospitalization
these
patients.
As
serious
conditions,
integrated,
multidisciplinary,
holistic
approach
indicated.
This
should
be
multimodal
include
non-pharmacological
therapies
alongside
pharmacological
approaches.
Health
care
aware
available
alternatives
when
first
choice
analgesic
fail.
Protocols
identification
type
prolonged
monitoring
clinical
status
implemented
improve
patient
well-being
during
acute
infection,
but
also
prevent
chronic
syndromes.
Monkeypox
is
a
rare,
zoonotic
viral
illness
that
was
initially
endemic
mainly
to
Africa.
The
virus
later
spread
non-African
countries
and,
in
2022,
it
exploded
on
global
scale,
with
an
unprecedented
number
of
cases.
rapid,
multi-country
transmission,
primarily
men
who
have
sex
(MSM),
and
evolving
clinical
manifestations
demographic
traits
the
current
outbreak
raised
serious
concerns
among
international
health
community.
An
in-depth
inquiry
into
past
present
outbreaks
are
required,
especially
when
contrasting
features
witnessed
across
outbreaks.
This
narrative
review
aims
summarize
evolution
epidemiology,
features,
mode
management
protocol
human
monkeypox
infection
(H-MPVX)
over
decades.
For
detailed
characterization
novelties
associated
would
facilitate
accurate
dissemination
information
policy-making,
we
performed
thorough
literature
search
for
MPVX
PubMed,
Google
Scholar,
Science
Direct,
using
appropriate
keywords
choose
relevant
articles.