Опубликована: Июль 31, 2024
Protons are gaining increasing attention as neurotransmitters due to their extraordinary abilities rapidly transfer electrical charge, mobilize cellular calcium and modulate ion channels. How all this is possible currently the subject of in-depth studies discussions concerning not only neurophysiology, but also biological materials for artificial intelligence. This review describes some biochemical mechanisms by which protons, in combination with calcium, can initiate firing sensory neurons transmit impulses across synapses, thus supporting action Na+ K+ ions shown Hodgkin Huxley. Furthermore, put forward how many hydrolases neurotransmitters, particularly glutamate, gamma-aminobutyric acid, adenosine triphosphate acetylcholine, able generate protons. The results numerous experimental works taken into consideration indicate that protons play a fundamental role both generation transmission nerve impulse.
Язык: Английский