Hyphae and Healthspan DOI Creative Commons
Patrick Chambers

Опубликована: Авг. 6, 2024

Candida overgrowth (CO) can induce an avalanche of health problems. Its hyphal wall contains epitopes that trigger not only gluten type antibodies (celiac disease) but also a plethora mannan related targeting Gq coupled GPCRs. These latter disrupt autonomic receptors, inducing POTS, loss taste and smell, many other symptoms. auto-antibodies chemotactic cytokine receptors (CCRs) pain, psoriasis, alopecia areata, vitiligo maladies. They target T cells otherwise suppress latent viruses, e.g., EBV. Hyphae release candidalysin, toxin suppresses growth competing intestinal bacteria, triggers inflammasomes, causes hypercitrullination. Anti-citrullinated peptide (ACPAs) are produced. B exposed to hyper citrullination develop citrullinated receptors. ACPAs CCRs may jointly viral reactivation from infected cells. EBV, in virtually all humans now free circulate, is targeted by these same ACPAs. EBV nuclear material released antinuclear (ANAs) emerge. the histamine tryptase mast Tryptase have been tightly linked trifecta cell activation syndrome (MCAS), hypermobility spectrum disorder (HSD), POTS addition long Covid (LC) probably anti-phospholipid (APS). periodontitis. Bacteria generally considered be culprits, hyphae its biofilm facilitate their pathogenesis. Periodontitis with sentinel risk indicator for cancer, dementia, autoimmune disease, ASCVD chronic disease general. D3 tryptophan oppose invasive transition Candida, which responds releasing indoleamine dioxygenase degrades tryptophan. This altered metabolism characteristic these. Ultimately directly or indirectly involved gut dysbiosis, including periodontitis, detriment healthspan. The approach conceptual empirical.

Язык: Английский

Hyphae and Healthspan DOI Creative Commons
Patrick Chambers

Опубликована: Авг. 1, 2024

Candida overgrowth (CO) can induce an avalanche of health problems. Its hyphal wall contains epitopes that trigger not only gluten type antibodies (celiac disease) but also a plethora mannan related targeting Gq coupled GPCRs. These latter disrupt autonomic receptors, inducing POTS, loss taste and smell, many other symptoms. auto-antibodies chemotactic cytokine receptors (CCRs) pain, psoriasis, alopecia areata, vitiligo maladies. They target T cells otherwise suppress latent viruses, e.g., EBV. Hyphae release candidalysin, toxin suppresses growth competing intestinal bacteria, triggers inflammasomes, causes hypercitrullination. Anti-citrullinated peptide (ACPAs) are produced. B exposed to hyper citrullination develop citrullinated receptors. ACPAs CCRs may jointly viral reactivation from infected cells. EBV, in virtually all humans now free circulate, is targeted by these same ACPAs. EBV nuclear material released antinuclear (ANAs) emerge. the histamine tryptase mast Tryptase have been tightly linked trifecta cell activation syndrome (MCAS), hypermobility spectrum disorder (HSD), POTS addition long Covid (LC) probably anti-phospholipid (APS). periodontitis. Bacteria generally considered be culprits, hyphae its biofilm facilitate their pathogenesis. Periodontitis with sentinel risk indicator for cancer, dementia, autoimmune disease, ASCVD chronic disease general. D3 tryptophan oppose invasive transition Candida, which responds releasing indoleamine dioxygenase degrades tryptophan. This altered metabolism characteristic these. Ultimately directly or indirectly involved gut dysbiosis, including periodontitis, detriment healthspan. The approach conceptual empirical.

Язык: Английский

Процитировано

2
Hyphae and Healthspan DOI Creative Commons
Patrick Chambers

Опубликована: Авг. 6, 2024

Candida overgrowth (CO) can induce an avalanche of health problems. Its hyphal wall contains epitopes that trigger not only gluten type antibodies (celiac disease) but also a plethora mannan related targeting Gq coupled GPCRs. These latter disrupt autonomic receptors, inducing POTS, loss taste and smell, many other symptoms. auto-antibodies chemotactic cytokine receptors (CCRs) pain, psoriasis, alopecia areata, vitiligo maladies. They target T cells otherwise suppress latent viruses, e.g., EBV. Hyphae release candidalysin, toxin suppresses growth competing intestinal bacteria, triggers inflammasomes, causes hypercitrullination. Anti-citrullinated peptide (ACPAs) are produced. B exposed to hyper citrullination develop citrullinated receptors. ACPAs CCRs may jointly viral reactivation from infected cells. EBV, in virtually all humans now free circulate, is targeted by these same ACPAs. EBV nuclear material released antinuclear (ANAs) emerge. the histamine tryptase mast Tryptase have been tightly linked trifecta cell activation syndrome (MCAS), hypermobility spectrum disorder (HSD), POTS addition long Covid (LC) probably anti-phospholipid (APS). periodontitis. Bacteria generally considered be culprits, hyphae its biofilm facilitate their pathogenesis. Periodontitis with sentinel risk indicator for cancer, dementia, autoimmune disease, ASCVD chronic disease general. D3 tryptophan oppose invasive transition Candida, which responds releasing indoleamine dioxygenase degrades tryptophan. This altered metabolism characteristic these. Ultimately directly or indirectly involved gut dysbiosis, including periodontitis, detriment healthspan. The approach conceptual empirical.

Язык: Английский

Процитировано

0