Russian Military Medical Academy Reports, Год журнала: 2024, Номер 43(3), С. 361 - 371
Опубликована: Ноя. 8, 2024
During its existence, electron microscopy has become one of the reference methods for assessing structural and functional state cells, tissues organs, an extensive evidence base been formed that allows use in creation formation a biobank. The selection sources literature review was carried out using keywords based on publications over past 20 years. presented were selected by searching eLIBRARY.RU, PubMed Scopus databases. Based foreign domestic experience work biobanks, we can distinguish four areas determine effectiveness studies as component work. Firstly, it is control microbiological contamination biological sample. detecting sample with bacteria, fungi viruses comparable to classical techniques. Secondly, diagnostic tool you identify or confirm presence pathogenetic process interest biobanking: tumor growth, atherosclerotic vessel damage, etc. Thirdly, quality cryopreservation samples. A wide range morphological characteristics ultramicroscopic structure cells microanatomical formations makes possible characterize quantify degree which contributes unification standardization biobanking. Transmission most informative this matter. Fourthly, basis digitalization results obtained interdisciplinary biobank repository, “big date” technologies fundamental research. compliance profile economic, scientific industrial infrastructure industry region great importance. Electron data are successfully combined molecular studies, metadata databases suitable interregional integrations. latter solve applied problems. above us consider scanning transmission key development biobanking region.
Язык: Английский