Characterizing and comparing phylogenies from their Laplacian spectrum DOI Creative Commons
Éric Lewitus, Hélène Morlon

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2015, Номер unknown

Опубликована: Сен. 9, 2015

Abstract Phylogenetic trees are central to many areas of biology, ranging from population genetics and epidemiology microbiology, ecology, macroevolution. The ability summarize properties trees, compare different identify distinct modes division within is essential all these research areas. But despite wide-ranging applications, there currently exists no common, comprehensive framework for such analyses. Here we present a graph-theoretical approach that provides framework. We show how construct the spectral density profiles phylogenetic their Laplacian graphs. Using ultrametric simulated as well non-ultrametric empirical demonstrate successfully identifies various clusters them into meaningful groups. Finally, illustrate eigengap can given tree. As data continue accumulate be integrated life sciences, expect this phylogenetics will have powerful long-lasting applications.

Язык: Английский

Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases DOI Creative Commons
Katharina C. Wollenberg Valero, Joan Garcia‐Porta, Ariel Rodríguez

и другие.

Nature Communications, Год журнала: 2017, Номер 8(1)

Опубликована: Май 15, 2017

Abstract Anuran amphibians undergo major morphological transitions during development, but the contribution of their markedly different life-history phases to macroevolution has rarely been analysed. Here we generate testable predictions for coupling versus uncoupling phenotypic evolution tadpole and adult phases, underlying expression genes related feature formation. We test these by combining evidence from gene in two distantly frogs, Xenopus laevis Mantidactylus betsileanus , with patterns entire radiation Madagascan mantellid frogs. Genes linked structure formation are expressed a highly phase-specific pattern, suggesting across phases. This pattern agrees uncoupled rates trait among mantellids, which show have undergone an adaptive radiation. Our results validate prevalence phenotypes

Язык: Английский

Процитировано

53
Characterizing and comparing phylogenies from their Laplacian spectrum DOI Creative Commons
Éric Lewitus, Hélène Morlon

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2015, Номер unknown

Опубликована: Сен. 9, 2015

Abstract Phylogenetic trees are central to many areas of biology, ranging from population genetics and epidemiology microbiology, ecology, macroevolution. The ability summarize properties trees, compare different identify distinct modes division within is essential all these research areas. But despite wide-ranging applications, there currently exists no common, comprehensive framework for such analyses. Here we present a graph-theoretical approach that provides framework. We show how construct the spectral density profiles phylogenetic their Laplacian graphs. Using ultrametric simulated as well non-ultrametric empirical demonstrate successfully identifies various clusters them into meaningful groups. Finally, illustrate eigengap can given tree. As data continue accumulate be integrated life sciences, expect this phylogenetics will have powerful long-lasting applications.

Язык: Английский

Процитировано

3