African Journal of Biology and Medical Research, Год журнала: 2024, Номер 7(2), С. 75 - 96

Опубликована: Апрель 29, 2024

Infertility, defined as the inability of couples to conceive after one year consistent, unprotected sexual contact, is a widespread concern affecting significant portion population. Notably, between 14 17% may encounter infertility at some point during their reproductive journey. This review delves into realm diagnosing male beyond conventional semen analysis. Conventional analysis, which globally accepted tool for infertility, primarily focuses on assessing sperm count, motility, viability, and morphology, leaving certain aspects functionality unexplored. These limitations necessitate integration advanced analysis techniques provide more comprehensive evaluation. Advanced encompasses range sophisticated tests that probe deeper intricacies fertility. include penetration capabilities, acrosomal discharge, spermatozoa Reactive Oxygen Species (ROS) levels. Moreover, like chromatin structure assay, DNA damage assessment, proteomics, metabolomics, high magnification microscopy, all shed light various facets function quality. While offer understanding uptake utilization in clinical practice have been limited. aims elucidate roles, merits, drawbacks both infertility. sheds strengths weaknesses each approach, it promotes nuanced approach diagnosis, enhancing prospects successful conception challenged couples.

Язык: Английский