The effect of anesthesia on postoperative cognitive dysfunction in adults undergoing cataract surgery: a systematic review
BMC Anesthesiology,
Год журнала:
2025,
Номер
25(1)
Опубликована: Янв. 23, 2025
We
systematically
reviewed
the
evidence
on
effect
of
anesthetic
methods
and
drugs
incidence
postoperative
cognitive
dysfunction
(POCD)
after
cataract
surgery.
The
Web
Science,
PubMed,
Scopus
databases
were
searched
for
relevant
English
reports
published
from
2000
to
August
2024.
After
full-text
screening
checking
quality
assessment
each
article
using
JBI
checklist,
9
articles
included
in
this
study.
explain
how
different
modalities
may
affect
POCD
Our
study
aimed
investigate
relationship
between
various
anesthesia
people
undergoing
clinical
trials
with
1014
participants,
which
analyzed
interventions.
Four
compared
modality
interventions
five
studies
POCD.
used
measurement
scales,
including
Mini-Mental
State
Examination,
Neurobehavioral
Rating
Scale,
Blessed
Orientation-Memory-Concentration
Test,
Iowa
Satisfaction
Anesthesia
scale,
PALT,
VF
test.
All
that
local
topical
found
no
statistically
significant
difference
at
postop
days
1
7.
General
cause
approximately
twofold
than
anesthesia.
Ketamine,
Midazolam,
or
Dexmedetomidine
seemed
reduce
complications
control
group.
This
systematic
review
investigates
techniques
available
literature
is
far
being
conclusive
further
are
needed
reach
any
conclusions.
It
necessary
adopt
an
appropriate
method
elderly
high-risk
patients,
especially
who
have
a
history
problems
elective
surgery,
surgery.
Язык: Английский
Sedation with midazolam in the NICU: implications on neurodevelopment
NeuroImmune Pharmacology and Therapeutics,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 23, 2024
Abstract
The
developing
brain,
particularly
in
premature
infants,
is
highly
susceptible
to
environmental
and
pharmacological
influences.
Premature
neonates
often
require
prolonged
stays
the
NICU,
where
midazolam
(MDZ),
a
benzodiazepine,
commonly
used
as
sedative,
despite
concerns
raised
by
FDA
2016
regarding
its
potential
neurological
complications
infants.
Understanding
long-term
effects
of
MDZ
on
these
vulnerable
patients
hindered
ethical
considerations
limited
research.
This
review
emphasizes
vulnerability
infants
sedation
anesthesia
outlines
how
early
exposure
can
impact
brain
development
at
both
molecular
behavioral
levels,
drawing
from
clinical
preclinical
data.
Additionally,
we
highlighted
existing
knowledge
gaps
suggested
avenues
for
further
research
better
comprehend
enduring
consequences
neurodevelopment
this
population.
Язык: Английский
Overcoming age: Slow anesthesia induction may prevent geriatric patients from developing burst suppression and help developing intraoperative EEG signatures of a younger brain
Journal of Clinical Anesthesia,
Год журнала:
2024,
Номер
99, С. 111672 - 111672
Опубликована: Окт. 31, 2024
Язык: Английский