Recent development and applications of electrodeposition biocoatings on medical titanium for bone repair

Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(39), С. 9863 - 9893

Опубликована: Янв. 1, 2024

Schematic diagram of the device, mechanism and biomedical application electrodeposition for preparation bioactive coatings on surface titanium implants bone repair.

Язык: Английский

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The rational design, biofunctionalization and biological properties of orthopedic porous titanium implants: a review

Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Фев. 26, 2025

Porous titanium implants are becoming an important tool in orthopedic clinical applications. This review provides a comprehensive survey of recent advances porous for use. First, the briefly describes characteristics bone and design requirements implants. Subsequently, pore size structural alloy materials presented, then we introduce application practice, including spine surgery, joint treatment tumors. Following that, describe surface modifications applied to obtain better biological functions. Finally, discuss incorporating environmental responsive mechanisms into achieve additional functionalities.

Язык: Английский

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Biocompatibility of Plasma Electrolytic Oxidation Coated Titanium Alloy for Biomedical Applications

BioNanoScience, Год журнала: 2025, Номер 15(2)

Опубликована: Фев. 11, 2025

Язык: Английский

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Enhanced Bioactivity and Mechanical Properties of Silicon-Infused Titanium Oxide Coatings Formed by Micro-arc Oxidation on Selective Laser Melted Ti13Nb13Zr Alloy

Ceramics International, Год журнала: 2024, Номер 50(21), С. 43979 - 43993

Опубликована: Авг. 15, 2024

Язык: Английский

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Microarc Oxidation Coatings Doped with a Low Proportion of Yttrium Enhance the Osseointegration of Titanium Implants through the BMP/Smad Pathway

ACS Biomaterials Science & Engineering, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Adding metal ions is a promising strategy to enhance the biological performance of titanium implants. In this study, we aimed explore effects yttrium on osseointegration First, series yttrium-doped surfaces were fabricated via microarc oxidation (MAO) by incorporating acetate into electrolyte, and then surface characteristics different substrates evaluated. Subsequently, cellular behaviors coatings assessed, osteointegration examined using rat model. Finally, high-throughput sequencing was employed elucidate underlying mechanisms MAO coatings. As results indicated, proportion in increased as concentration improved. Surface characterization revealed that exhibited homogeneous porous morphology, with comparable roughness wettability those undoped coating, while morphology became inconsistent when reached 30 mM. The vitro assays demonstrated addition notably improved cell adhesion, spreading, proliferation, osteogenic differentiation doped low proportion, accompanied enhanced according vivo experiments. Further exploration significant enrichment osseointegration-related signaling factors activation BMP/Smad coatings, which attributed excessive accumulation phosphorylated Smad1/5/9 nucleus. summary, our work demonstrates use can implants, providing an efficient optimize implant performance.

Язык: Английский

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Enhanced corrosion resistance and biocompatibility of Ti implants by Si-doped coatings

Bioinspired Biomimetic and Nanobiomaterials, Год журнала: 2025, Номер unknown, С. 1 - 13

Опубликована: Март 19, 2025

In this study, we prepared a silicon-containing electrolyte solution and titanium dioxide coating (Si–TiO 2 ) on the surface of medical by way microarc oxidation. The properties formed Si–TiO were evaluated using field emission scanning electron microscopy, energy dispersive spectroscopy, X-ray diffraction (XRD), profilometer. corrosion resistance was an electrochemical workstation. biocompatibility biological activity in vitro cell culture. results indicated that could be successfully deposited oxidation, XRD confirmed mainly composed dioxide. Nyquist curve Tafel improved titanium. experiments promoted adhesion proliferation MC3T3-E1 cells. conclusion, oxidation used to introduce silicon onto implants, porous not only wear but also had good activity. Thus, use implants warrants further research for potential clinical applications.

Язык: Английский

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Design and Fabrication of Bioactive and Antibacterial LIPSS Surfaces on Titanium Alloy by Femtosecond Laser

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

A titanium alloy is widely used in implants for its excellent mechanical properties and corrosion resistance. However, the bonding strength between a bone tissue low, bacterial adhesion easily triggered on implant surface, which may cause failure of implants. Therefore, surface modification necessary to improve biological activity antibacterial properties. In this work, four different types laser-induced periodic structure (LIPSS) surfaces are designed fabricated TiNi by femtosecond laser according size MC3T3-E1 mouse embryonic osteoblasts. The vitro osteogenic LIPSS investigated. It found that helps activity, bonelike apatite tends deposit distribute LIPSS. evaluated through cell culture experiments Escherichia coli experiments. demonstrated horizontal sample with width 30 μm has highest proliferation rate (142.5% after 1 day, 132.3% 3 days) good (50.2%). These results provide guidance application biocompatibility aspects.

Язык: Английский

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Engineered porous bio-ceramic coating with antibacterial and excellent biocompatibility on the surface of low modulus multi-component titanium alloy

Surface and Coatings Technology, Год журнала: 2025, Номер unknown, С. 132121 - 132121

Опубликована: Апрель 1, 2025

Язык: Английский

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Development of an Alginate Gel Composite with Antibacterial Properties Capable of Binding Calcium-Based Residual Stone Fragments in Endoscopic Stone Surgery

Journal of Endourology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 8, 2025

Background: Complete removal of urinary stones remains a challenge, as residual fragments can contribute to recurrence and postoperative tract infections. This study presents an initial laboratory investigation into the development alginate gel composite designed bind calcium-based stone remnants exhibit antibacterial properties. Methods: To evaluate formation, calcium oxalate powder reagent sodium (SA) were mixed in Becker glass stirred on hot plate. Stones from 17 patients who underwent surgery crushed, formation was confirmed using same experimental conditions with SA reagent. A material containing silver nitrate vancomycin prepared, activity against Staphylococcus aureus Escherichia coli tested over 5-minute period. mixture 0.5 g alginic acid 0.05 monohydrate 50 mL distilled water formed after 30 minutes. Results: Sandy composed better when than those uric acid. In test S. E. coli, number live bacteria control 3.5 × 103 <10, respectively. Conclusion: represents preliminary for potential use management. Further preclinical studies are necessary its efficacy safety before clinical translation.

Язык: Английский

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Development of Functionally Graded Films and Coatings for Biomaterials: Methods, properties, and challenges – A comprehensive review

Tribology International, Год журнала: 2025, Номер unknown, С. 110714 - 110714

Опубликована: Апрель 1, 2025

Язык: Английский

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