American Journal of Medical Genetics Part A,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 15, 2025
ABSTRACT
Artificial
intelligence
(AI)
is
rapidly
transforming
numerous
aspects
of
daily
life,
including
clinical
practice
and
biomedical
research.
In
light
this
rapid
transformation,
in
the
context
medical
genetics,
we
assembled
a
group
leaders
field
to
respond
question
about
how
AI
affecting,
especially
will
affect,
genetics.
The
authors
who
contributed
collection
essays
intentionally
represent
different
areas
expertise,
career
stages,
geographies,
include
diverse
types
clinicians,
computer
scientists,
researchers.
individual
pieces
cover
wide
range
related
genetics;
expect
that
these
may
provide
helpful
windows
into
ways
which
being
actively
studied,
used,
considered
Future Internet,
Год журнала:
2025,
Номер
17(4), С. 145 - 145
Опубликована: Март 26, 2025
The
rapid
emergence
of
infectious
disease
outbreaks
has
underscored
the
urgent
need
for
effective
communication
tools
to
manage
public
health
crises.
Artificial
Intelligence
(AI)-based
chatbots
have
become
increasingly
important
in
these
situations,
serving
as
critical
resources
provide
immediate
and
reliable
information.
This
review
examines
role
AI-based
emergencies,
particularly
during
outbreaks.
By
providing
real-time
responses
inquiries,
help
disseminate
accurate
information,
correct
misinformation,
reduce
anxiety.
Furthermore,
AI
play
a
vital
supporting
healthcare
systems
by
triaging
offering
guidance
on
symptoms
preventive
measures,
directing
users
appropriate
services.
not
only
enhances
access
information
but
also
helps
alleviate
workload
professionals,
allowing
them
focus
more
complex
tasks.
However,
implementation
is
without
challenges.
Issues
such
accuracy
user
trust,
ethical
considerations
regarding
data
privacy
are
factors
that
be
addressed
optimize
their
effectiveness.
Additionally,
adaptability
rapidly
evolving
scenarios
essential
sustained
relevance.
Despite
challenges,
potential
AI-driven
transform
emergencies
significant.
highlights
importance
continuous
development
integration
into
strategies
enhance
preparedness
response
efforts
Their
accessible,
accurate,
timely
makes
indispensable
modern
emergency
management.
Pharmaceutics,
Год журнала:
2025,
Номер
17(5), С. 555 - 555
Опубликована: Апрель 24, 2025
Background:
Advancements
in
pharmacogenomics,
artificial
intelligence
(AI),
and
CRISPR
gene-editing
technology
are
revolutionizing
precision
medicine
by
enabling
highly
individualized
therapeutic
strategies.
Artificial
intelligence-driven
computational
techniques
improve
biomarker
discovery
drug
optimization
while
pharmacogenomics
helps
to
identify
genetic
polymorphisms
affecting
metabolism,
efficacy,
toxicity.
Genetically
editing
based
on
presents
a
precise
method
for
changing
gene
expression
repairing
damaging
mutations.
This
review
explores
the
convergence
of
these
three
fields
enhance
improved
medicine.
Method:
A
methodical
study
current
literature
was
performed
effects
response
variability,
intelligence,
predictive
modeling
applications.
Results:
Driven
allows
clinicians
classify
patients
select
appropriate
medications
depending
their
DNA
profiles.
reduces
side
effect
risk
increases
efficacy.
Precision
modifications
made
feasible
therapy
outcomes
oncology,
metabolic
illnesses,
neurological
diseases,
other
fields.
The
integration
streamlines
genome-editing
applications,
lowers
off-target
effects,
specificity.
Notwithstanding
advances,
issues
including
biases,
moral
dilemmas,
legal
constraints
still
arise.
Conclusions:
synergy
alters
letting
customized
interventions.
Clinically
translating,
however,
hinges
resolving
data
privacy
concerns,
assuring
equitable
access,
strengthening
systems.
Future
research
should
focus
refining
technologies,
enhancing
AI-driven
developing
guidelines
applying
tools
going
forward.
Intrinsically
disordered
proteins
(IDPs)
and
biomolecular
condensates
are
critical
for
cellular
processes
physiological
functions.
Abnormal
can
cause
diseases
such
as
cancer
neurodegenerative
disorders.
IDPs,
including
intrinsically
regions
(IDRs),
were
previously
considered
undruggable
due
to
their
lack
of
stable
binding
pockets.
However,
recent
evidence
indicates
that
targeting
them
influence
processes.
This
review
explores
current
strategies
target
IDPs
condensates,
potential
improvements,
the
challenges
opportunities
in
this
evolving
field.
American Journal of Medical Genetics Part A,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 15, 2025
ABSTRACT
Artificial
intelligence
(AI)
is
rapidly
transforming
numerous
aspects
of
daily
life,
including
clinical
practice
and
biomedical
research.
In
light
this
rapid
transformation,
in
the
context
medical
genetics,
we
assembled
a
group
leaders
field
to
respond
question
about
how
AI
affecting,
especially
will
affect,
genetics.
The
authors
who
contributed
collection
essays
intentionally
represent
different
areas
expertise,
career
stages,
geographies,
include
diverse
types
clinicians,
computer
scientists,
researchers.
individual
pieces
cover
wide
range
related
genetics;
expect
that
these
may
provide
helpful
windows
into
ways
which
being
actively
studied,
used,
considered
